Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   GOM48_RS01570 Genome accession   NZ_CP046523
Coordinates   326885..327517 (+) Length   210 a.a.
NCBI ID   WP_235097937.1    Uniprot ID   -
Organism   Streptococcus oralis strain SOD     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 321885..332517
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM48_RS01545 (GOM48_01535) mvaD 322081..323034 (+) 954 WP_235097929.1 diphosphomevalonate decarboxylase -
  GOM48_RS01550 (GOM48_01540) - 323021..324028 (+) 1008 WP_235097931.1 phosphomevalonate kinase -
  GOM48_RS01555 (GOM48_01545) fni 324012..325013 (+) 1002 WP_235097933.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  GOM48_RS01560 (GOM48_01550) liaF 325181..325879 (+) 699 WP_223326118.1 cell wall-active antibiotics response protein LiaF -
  GOM48_RS01565 (GOM48_01555) - 325876..326871 (+) 996 WP_235097935.1 sensor histidine kinase -
  GOM48_RS01570 (GOM48_01560) vraR 326885..327517 (+) 633 WP_235097937.1 response regulator transcription factor Regulator
  GOM48_RS01575 (GOM48_01570) - 327518..328175 (+) 658 Protein_277 DNA alkylation repair protein -
  GOM48_RS01580 (GOM48_01575) tig 328268..329551 (+) 1284 WP_235097939.1 trigger factor -
  GOM48_RS01585 (GOM48_01580) recD/recD2/recDB 329599..331968 (-) 2370 WP_235097942.1 ATP-dependent RecD-like DNA helicase Machinery gene

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23718.32 Da        Isoelectric Point: 4.8067

>NTDB_id=352675 GOM48_RS01570 WP_235097937.1 326885..327517(+) (vraR) [Streptococcus oralis strain SOD]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEATNGAQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGAKGYMLKTSSADELLHAVRKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVRQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=352675 GOM48_RS01570 WP_235097937.1 326885..327517(+) (vraR) [Streptococcus oralis strain SOD]
ATGAAAATTTTACTGGTAGATGACCATGAAATGGTTCGATTGGGCTTGAAAAGCTATTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGCGAGGCTACCAATGGGGCTCAAGGTATTGACTTGGCCTTGGAATTGCGTCCAGATGTCATTGTCATGGATA
TTGTTATGCCTGAGATGAATGGAATTGATGCTACCTTGGCCATCCTCAAAGAATGGCCTGAAGCCAAGATTTTGATTGTG
ACCTCTTACTTGGACAATGAAAAAATCATGCCAGTCTTGAATGCTGGTGCAAAAGGCTATATGCTTAAGACTTCAAGTGC
AGATGAATTGCTCCATGCTGTCCGTAAGGTGGCTGCTGGCGAGCTGGCCATTGAACAAGAGGTCAGCAAGAAGGTTGAAT
ACCACCGTAATCATATGGAGCTTCATGAGGAGCTGACTGCGCGTGAGCGAGACGTACTTCAACTGATCGCTAAGGGCTAC
GAAAATCAACGCATTGCAGATGAACTCTTTATCTCTCTCAAGACGGTCAAGACCCATGTGTCCAATATCCTTGCCAAGCT
TGAGGTCAGTGATCGCACTCAAGCTGCGGTCTATGCCTTTCAGCACCACTTGGTCAGGCAGGAGGATTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-115)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.905

100

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41

Multiple sequence alignment