Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   GE024_RS00860 Genome accession   NZ_CP046521
Coordinates   141726..142001 (+) Length   91 a.a.
NCBI ID   WP_003046190.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_100     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 136726..147001
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE024_RS00835 (GE024_00825) - 138656..139021 (+) 366 WP_003046179.1 DUF1033 family protein -
  GE024_RS00840 (GE024_00830) comGA 139108..140049 (+) 942 WP_003046182.1 competence type IV pilus ATPase ComGA Machinery gene
  GE024_RS00845 (GE024_00835) comGB 139982..141016 (+) 1035 WP_223824829.1 competence type IV pilus assembly protein ComGB Machinery gene
  GE024_RS00850 (GE024_00840) comGC/cglC 141019..141345 (+) 327 WP_003046186.1 competence type IV pilus major pilin ComGC Machinery gene
  GE024_RS00855 (GE024_00845) comGD 141320..141748 (+) 429 WP_039994748.1 competence type IV pilus minor pilin ComGD Machinery gene
  GE024_RS00860 (GE024_00850) comGE 141726..142001 (+) 276 WP_003046190.1 competence type IV pilus minor pilin ComGE Machinery gene
  GE024_RS00865 (GE024_00855) comGF 141982..142422 (+) 441 WP_003046192.1 competence type IV pilus minor pilin ComGF Machinery gene
  GE024_RS00870 (GE024_00860) comGG 142400..142780 (+) 381 WP_003046193.1 competence type IV pilus minor pilin ComGG -
  GE024_RS00875 (GE024_00865) comGH 142830..143783 (+) 954 WP_003046195.1 class I SAM-dependent methyltransferase Machinery gene
  GE024_RS00880 (GE024_00870) - 143842..145038 (+) 1197 WP_093998734.1 acetate kinase -
  GE024_RS00885 (GE024_00875) - 145330..145536 (+) 207 WP_003046200.1 helix-turn-helix transcriptional regulator -
  GE024_RS11045 (GE024_00885) - 145694..146131 (+) 438 WP_164403311.1 hypothetical protein -

Sequence

Protein


Download         Length: 91 a.a.        Molecular weight: 10262.90 Da        Isoelectric Point: 7.2771

>NTDB_id=352553 GE024_RS00860 WP_003046190.1 141726..142001(+) (comGE) [Streptococcus canis strain HL_100]
MKGYIALESVMATGLLFSIVILVLTSLQQGQVALTHYRNQQEKLNLALMAVQTGREEVTLNGCHITVRRTEHQISIQDDK
GEVIRIEQKDK

Nucleotide


Download         Length: 276 bp        

>NTDB_id=352553 GE024_RS00860 WP_003046190.1 141726..142001(+) (comGE) [Streptococcus canis strain HL_100]
GTGAAAGGTTACATAGCCCTTGAAAGTGTGATGGCGACAGGGCTCTTATTTTCCATTGTTATCCTAGTTTTGACTAGTTT
ACAGCAAGGTCAGGTCGCCCTAACCCATTATCGCAATCAACAAGAAAAACTGAATTTGGCGCTGATGGCAGTACAGACAG
GTCGTGAAGAAGTCACACTCAATGGCTGTCATATTACTGTTCGGAGAACGGAACATCAGATTAGTATTCAGGACGATAAA
GGAGAAGTGATTAGGATTGAACAAAAGGACAAATAG

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(5-86)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

38.202

97.802

0.374
  comGE Streptococcus mutans UA159

38.202

97.802

0.374