Detailed information NTG0035252

Bioinformatically predicted

Overview

• Name: mutS/mutS2
• Type: Machinery gene
• Locus tag: MGAS1882_RS07095
• Genome accession: NC_017053
• Coordinates: 1442289..1444628 (-)
• Length: 779 a.a.
• NCBI ID: WP_014407818.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes MGAS1882
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1437289..1449628

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS1882_RS07055 (MGAS1882_1457)	rpsR	1437581..1437820 (-)	240	WP_002983142.1	30S ribosomal protein S18	-
MGAS1882_RS07060 (MGAS1882_1458)	ssb	1437984..1438475 (-)	492	WP_002983122.1	single-stranded DNA-binding protein	Machinery gene
MGAS1882_RS07065 (MGAS1882_1459)	rpsF	1438497..1438787 (-)	291	WP_002983117.1	30S ribosomal protein S6	-
MGAS1882_RS07070 (MGAS1882_1460)	-	1438960..1439253 (-)	294	WP_002983113.1	hypothetical protein	-
MGAS1882_RS07075 (MGAS1882_1461)	mutY	1439421..1440575 (+)	1155	WP_014407816.1	A/G-specific adenine glycosylase	-
MGAS1882_RS07080 (MGAS1882_1462)	-	1440752..1441338 (+)	587	Protein_1354	helix-turn-helix domain-containing protein	-
MGAS1882_RS07085 (MGAS1882_1463)	trxA	1441390..1441722 (-)	333	WP_001932060.1	thioredoxin	-
MGAS1882_RS07090 (MGAS1882_1464)	-	1441785..1442285 (-)	501	WP_014407817.1	phosphatase PAP2 family protein	-
MGAS1882_RS07095 (MGAS1882_1465)	mutS/mutS2	1442289..1444628 (-)	2340	WP_014407818.1	endonuclease MutS2	Machinery gene
MGAS1882_RS07100 (MGAS1882_1466)	-	1444777..1445322 (-)	546	WP_002983087.1	CvpA family protein	-
MGAS1882_RS07105 (MGAS1882_1467)	-	1445325..1445633 (-)	309	WP_002993251.1	hypothetical protein	-
MGAS1882_RS07110 (MGAS1882_1468)	rnhC	1445790..1446692 (+)	903	WP_010922635.1	ribonuclease HIII	-
MGAS1882_RS07115 (MGAS1882_1469)	lepB	1446703..1447296 (+)	594	WP_002983074.1	signal peptidase I	-

Sequence

Protein

• Length: 779 a.a.
• Molecular weight: 87855.08 Da
• Isoelectric Point: 6.4510

>NTDB_id=35252 MGAS1882_RS07095 WP_014407818.1 1442289..1444628(-) (mutS/mutS2) [Streptococcus pyogenes MGAS1882]
MNNKILEQLEFNKVKELLLPYLKTEQSQEELLELEPMTEAPKIEKSFNEISDMEQIFVEHHSFGIVSLSSISESLKRLEL
SADLNIQELLAIKKVLQSSSDMIHFYSDLDNVSFQSLDRLFENLEQFPNLQGSFQAINDGGFLEHFASPELERIRRQLTN
SERRVRQILQDMLKEKAELLSENLIASRSGRSVLPVKNTYRNRISGVVHDISSSGSTVYIEPRAVVTLNEEITQLRADER
HEEGRILHTFSDLLRPHVATIRNNAWILGHLDFVRAKYLFMSDNKATIPKISDDSTLALINVRHPLLSNPVANDLHFDHD
LTAIVITGPNTGGKTIMLKTLGLAQLMGQSGLPVLADKGSKITVFNNIFADIGDEQSIEQSLSTFSSHMTHIVSILNEAD
RNSLVLFDELGAGTDPQEGASLAMAILEHLRLSHIKTMATTHYPELKAYGIETNFVENASMEFDAETLSPTYRFMQGVPG
RSNAFEIASRLGLAPFIVKQAKQMTDSDSDVNRIIEQLEAQTLETRRRLDHIKEVEQENLKFNRAVKKLYNEFSHERDKE
LEKIYQEAQEIVDMALNESDTILKKLNDKSQLKPHEIIDAKAQIKKLAPQVDLSKNKVLNKAKKIKAARAPRIGDDIIVT
SYGQRGTLTSQLKDGRWEAQVGIIKMTLTQDEFTLVRVQEEQKVKSKQINVVKKADSAGPRARLDLRGKRYEEAMQELDH
FIDQALLNNMGQVDIIHGIGTGVIREGVTKYLRRNKHVKHFAYAPQNAGGSGATIVTLG

Nucleotide

• Length: 2340 bp

>NTDB_id=35252 MGAS1882_RS07095 WP_014407818.1 1442289..1444628(-) (mutS/mutS2) [Streptococcus pyogenes MGAS1882]
ATGAATAACAAGATTTTAGAGCAGTTAGAATTTAACAAAGTTAAGGAATTGCTATTACCTTATCTTAAGACAGAACAATC
ACAAGAAGAATTATTAGAGCTGGAGCCGATGACGGAGGCTCCTAAAATAGAAAAAAGTTTTAATGAAATTTCTGACATGG
AACAGATTTTTGTTGAACATCACTCATTTGGCATAGTCAGCCTAAGTTCAATCTCTGAGAGTTTAAAACGCTTAGAGCTT
TCAGCTGATCTTAATATTCAAGAACTTTTGGCTATCAAAAAAGTTTTACAGAGTTCTTCGGATATGATTCACTTTTATTC
TGATTTGGATAATGTTTCTTTCCAATCTTTGGATCGTTTGTTTGAAAATTTGGAACAATTCCCTAATCTGCAAGGGTCTT
TTCAAGCTATCAATGATGGTGGTTTTTTAGAACATTTTGCGAGTCCAGAATTAGAGCGTATCCGTCGTCAATTAACAAAT
AGTGAACGACGGGTTCGTCAGATTTTACAGGATATGCTTAAGGAAAAAGCAGAGCTTTTATCAGAGAATCTAATCGCTAG
TCGTAGTGGACGAAGTGTCCTACCAGTAAAAAATACTTATCGGAATCGTATTTCTGGTGTGGTTCATGACATCTCTTCTT
CAGGAAGTACTGTTTATATTGAGCCTCGTGCTGTAGTTACACTAAACGAAGAGATAACGCAGCTTAGAGCTGACGAACGC
CACGAAGAAGGTCGTATTTTACACACATTTTCAGACTTGTTAAGACCTCATGTCGCCACTATTAGAAATAATGCATGGAT
TCTTGGGCATCTTGATTTTGTAAGGGCTAAATATCTTTTTATGTCTGATAATAAGGCGACGATACCTAAGATCTCTGATG
ACAGCACGTTAGCATTAATCAATGTTCGTCATCCTCTGTTAAGTAATCCTGTGGCTAATGACTTACATTTTGATCACGAT
TTAACTGCAATTGTCATCACTGGTCCCAATACTGGTGGTAAGACGATTATGCTAAAAACACTCGGTTTAGCACAATTAAT
GGGACAGTCTGGTTTGCCAGTATTAGCGGATAAAGGTAGTAAAATTACAGTATTTAACAATATCTTTGCAGATATTGGCG
ATGAGCAATCTATTGAACAAAGTCTATCAACTTTTTCTAGTCATATGACGCACATAGTCAGTATTTTAAACGAGGCTGAC
CGCAATAGTTTAGTTCTCTTTGATGAACTGGGAGCAGGAACGGATCCTCAAGAAGGTGCTAGTTTGGCTATGGCTATTTT
AGAACACCTTAGGTTAAGTCATATCAAAACGATGGCGACCACGCACTATCCAGAATTAAAAGCTTATGGGATTGAGACAA
ATTTTGTAGAGAATGCGAGCATGGAATTTGATGCAGAAACGCTTAGCCCTACGTATCGCTTTATGCAAGGAGTTCCTGGA
CGCTCAAATGCATTTGAAATTGCTTCTCGCCTTGGTTTAGCTCCATTTATTGTTAAACAAGCTAAGCAGATGACAGATTC
TGACTCAGATGTTAACCGTATTATTGAACAGTTAGAGGCACAGACACTTGAGACACGTAGAAGACTGGATCATATTAAAG
AAGTTGAACAAGAAAACCTCAAATTCAATCGTGCGGTTAAGAAACTCTATAATGAATTTTCACATGAGCGCGATAAAGAG
TTAGAAAAAATCTATCAAGAAGCTCAAGAAATTGTAGATATGGCTTTGAATGAGAGTGATACTATCTTAAAAAAACTCAA
TGATAAGAGCCAATTAAAACCTCACGAAATTATAGATGCTAAGGCACAAATAAAAAAATTAGCGCCTCAAGTTGATTTAT
CAAAAAATAAAGTCTTAAATAAGGCTAAAAAAATCAAAGCAGCTCGTGCTCCTAGAATTGGTGATGATATTATAGTGACT
AGTTATGGACAGCGAGGTACCTTAACTAGTCAATTAAAAGATGGCCGTTGGGAAGCACAAGTGGGAATTATCAAAATGAC
ATTAACACAAGATGAATTTACCCTTGTTAGAGTCCAAGAAGAACAGAAAGTCAAAAGTAAACAGATTAATGTGGTTAAAA
AGGCTGATAGTGCTGGACCAAGAGCTCGACTTGATCTTAGAGGTAAAAGATACGAAGAAGCTATGCAAGAGTTAGATCAT
TTTATTGATCAAGCATTGCTTAACAATATGGGACAAGTTGATATCATTCATGGTATTGGTACAGGCGTTATTCGTGAGGG
AGTGACAAAATATCTTCGTCGTAATAAGCATGTTAAGCATTTTGCTTATGCCCCACAAAATGCAGGGGGATCTGGTGCCA
CAATTGTAACGTTAGGGTAA

Domains

Predicted by InterProScan.

• Smr domain (Smr) (704-778)

• MutS domain V (MutS_V) (324-505)

• MutS2 and Smr-associated SH3 domain (MSSS) (633-669)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
mutS/mutS2	Bacillus subtilis subsp. subtilis str. 168	40.506	100	0.411