Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E4J95_RS09930 Genome accession   NZ_CP038229
Coordinates   2032089..2032805 (+) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain MJ163     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2027089..2037805
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E4J95_RS09900 (E4J95_10370) - 2027308..2027934 (+) 627 WP_000522384.1 nitroreductase family protein -
  E4J95_RS09905 (E4J95_10375) - 2028295..2029080 (+) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  E4J95_RS13705 (E4J95_10380) - 2029677..2029811 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  E4J95_RS09915 (E4J95_10385) agrB 2030047..2030616 (+) 570 WP_001105707.1 accessory gene regulator AgrB -
  E4J95_RS09920 (E4J95_10390) agrD 2030613..2030753 (+) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  E4J95_RS09925 (E4J95_10395) agrC 2030778..2032070 (+) 1293 WP_001789596.1 quorum-sensing sensor histidine kinase AgrC -
  E4J95_RS09930 (E4J95_10400) agrA 2032089..2032805 (+) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  E4J95_RS09935 (E4J95_10405) - 2032877..2032986 (+) 110 Protein_1928 hypothetical protein -
  E4J95_RS09940 (E4J95_10410) - 2033174..2034133 (-) 960 WP_169449294.1 carbohydrate kinase -
  E4J95_RS09945 (E4J95_10415) - 2034130..2035614 (-) 1485 WP_000141416.1 sucrose-6-phosphate hydrolase -
  E4J95_RS09950 (E4J95_10420) - 2035763..2036713 (-) 951 WP_000790325.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=352457 E4J95_RS09930 WP_000688498.1 2032089..2032805(+) (agrA) [Staphylococcus aureus strain MJ163]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=352457 E4J95_RS09930 WP_000688498.1 2032089..2032805(+) (agrA) [Staphylococcus aureus strain MJ163]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGTTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment