Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   MGAS1882_RS02995 Genome accession   NC_017053
Coordinates   597026..600658 (+) Length   1210 a.a.
NCBI ID   WP_014411833.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS1882     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 592026..605658
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS1882_RS02985 (MGAS1882_0617) - 592746..593663 (-) 918 WP_012560586.1 neutral zinc metallopeptidase -
  MGAS1882_RS02990 (MGAS1882_0618) rexB 593814..597029 (+) 3216 WP_014407470.1 ATP-dependent nuclease subunit B Machinery gene
  MGAS1882_RS02995 (MGAS1882_0619) rexA 597026..600658 (+) 3633 WP_014411833.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  MGAS1882_RS03000 (MGAS1882_0620) - 600798..601610 (+) 813 WP_002990394.1 transporter substrate-binding domain-containing protein -
  MGAS1882_RS03005 (MGAS1882_0621) rpsU 601751..601927 (+) 177 WP_000048058.1 30S ribosomal protein S21 -
  MGAS1882_RS03010 (MGAS1882_0622) mscL 602055..602417 (-) 363 WP_014407472.1 large conductance mechanosensitive channel protein MscL -
  MGAS1882_RS03015 (MGAS1882_0623) dnaG 602547..604361 (+) 1815 WP_014407473.1 DNA primase -
  MGAS1882_RS03020 (MGAS1882_0624) rpoD 604370..605479 (+) 1110 WP_002985187.1 RNA polymerase sigma factor RpoD -

Sequence

Protein


Download         Length: 1210 a.a.        Molecular weight: 138895.01 Da        Isoelectric Point: 6.5510

>NTDB_id=35213 MGAS1882_RS02995 WP_014411833.1 597026..600658(+) (rexA) [Streptococcus pyogenes MGAS1882]
MISFAPFLSPEAIKHLQENERCSDQSQKRTAQQIEAIYTSGQNILVSASAGSGKTFVMVERILDKILRGVSIDRLFISTF
TVKAATELRERIENKLYSQIAQTTDFQMKVYLTEQLQSLCQADIGTMDAFAQKVVSRYGYSIGISSQFRIMQDKAEQDVL
KQEVFSKLFSEFMNQKEAPAFRALVKNFSGNCKDTSAFRELVYTCYSFSQSTENPKIWLQENFLSAAKTYQRLEDIPDHD
IELLLLAMQDTANQLRDVTDMEDYGQLTKAGSRSAKYTKHLTIIEKLSDWVRDFKCLYGKAGLDRLIRDVTGLIPSGNDV
TVSKVKYPVFKTLHQKLKQFRHLETILMYQKDCFPLLEQLQDFVLAFSEAYLAVKIQESAFEFSDIGHFAIKILEENTDI
RQSYQQHYHEVMVDEYQDNNHMQERLLTLLSNGHNRFMVGDIKQSIYRFRQADPQIFNQKFRDYQKKTEQGKVILLKENF
RSQSEVLNVSNAVFSHLMDESVGDVLYDEQHQLIAGSHAQTVPYLDRRAQLLLYNSDKDDGNAPSDSEDISFSEVTIVAK
EIIKLHNDKGVPFEDITLLVSSRTRNDIISHTFNQYGIPIVTDGGQQNYLKSVEVMVMLDTLRTINNPRNDYALVALLRS
PMFAFDEDDLARIALQKDNELDKDCLYDKIQRAVIGRGAYPELIHDTLLGKLNVFLKTLKSWRRYAKLGSLYDLIWKIFN
DRFYFDFVASQAKAEQAQANLYALALRANQFEKSGYKGLYRFIKMIDKVLETQNDLADVEVAAPKQAVNLMTIHKSKGLQ
FPYVFILNCDKRFSMTDIHKSFILNRQHGIGIKYLADIKGLLGETTLNSVKVSMETLPYQLNKQELRLATLSEQMRLLYV
AMTRAEKKVYFIGKASKSKSQEITDPKKLGKLLPLALREQLLTFQDWLLAIADIFSTEDLYFDVRFIEDSDLTQESVGRL
QTPQLLNPDDLKDNRQSETIARALDMLEAVSQLNANYEAAIHLPTVRTPSQLKAAYEPLLEPIGVDIIEKSSRSLSDFTL
PHFSKKAKVEASHIGSALHQLMQVLPLSKPINQQTLLDALRGIDSNEEVKTALDLKKIESFFCDTSLGQFFQTYQKHLYR
EAPFAILKVDPISQEEYVLRGIIDAYFLFDDHIVLVDYKTDKYKQPIELKKRYQQQLELYAEALTQTYKLPVTKRYLVLM
GGGKPEIVEV

Nucleotide


Download         Length: 3633 bp        

>NTDB_id=35213 MGAS1882_RS02995 WP_014411833.1 597026..600658(+) (rexA) [Streptococcus pyogenes MGAS1882]
GTGATTTCTTTTGCCCCATTTTTAAGCCCCGAAGCTATTAAACATTTACAAGAAAACGAAAGGTGCAGTGATCAGTCTCA
AAAACGCACAGCTCAACAAATTGAAGCAATTTATACTAGTGGCCAAAATATACTTGTATCAGCTTCTGCTGGTTCAGGAA
AAACCTTTGTAATGGTCGAACGCATACTTGATAAAATTTTGAGAGGTGTTTCAATTGATCGGCTTTTTATCTCAACCTTT
ACTGTTAAAGCAGCTACAGAACTGCGTGAACGGATTGAAAACAAATTATACTCACAAATTGCTCAAACTACAGATTTTCA
AATGAAAGTTTATTTAACAGAACAATTGCAATCTCTTTGTCAAGCTGATATTGGTACTATGGATGCTTTTGCACAGAAAG
TAGTAAGTCGCTATGGTTATAGCATTGGCATTTCATCCCAATTTCGTATCATGCAGGATAAAGCAGAACAAGATGTTTTA
AAGCAAGAGGTGTTTAGCAAACTCTTTAGTGAGTTTATGAATCAAAAAGAGGCACCGGCGTTTAGGGCTCTTGTGAAAAA
TTTTTCTGGTAACTGTAAAGACACTTCAGCTTTTAGAGAGTTAGTTTATACTTGTTATTCTTTTAGCCAATCGACAGAAA
ATCCAAAAATATGGTTGCAAGAAAATTTTCTAAGCGCTGCTAAAACTTACCAAAGACTTGAAGATATCCCGGATCATGAT
ATTGAACTCTTACTTTTGGCAATGCAAGACACTGCAAATCAGCTAAGAGATGTGACTGATATGGAAGATTATGGGCAGCT
GACTAAGGCAGGTAGCCGATCTGCTAAATACACTAAACACTTAACGATCATAGAAAAGTTGTCTGATTGGGTGCGTGATT
TTAAATGTTTGTATGGAAAAGCCGGATTGGATCGGTTGATCAGAGATGTGACAGGCCTTATACCATCTGGGAATGATGTT
ACAGTCTCGAAGGTAAAATACCCTGTTTTTAAGACCTTGCATCAAAAATTAAAACAATTTAGGCATTTAGAAACAATTTT
AATGTATCAGAAAGACTGTTTTCCTTTATTGGAACAGTTACAAGATTTTGTGCTTGCGTTTTCAGAAGCTTATTTAGCTG
TCAAAATACAAGAAAGTGCTTTTGAATTTTCAGATATTGGACACTTTGCAATCAAAATTTTAGAGGAAAATACGGATATT
CGCCAATCCTATCAGCAACACTATCATGAGGTGATGGTTGATGAATATCAAGATAACAATCATATGCAAGAGCGACTCCT
GACCTTACTATCGAACGGTCATAATCGCTTTATGGTAGGAGATATCAAACAATCGATCTATCGATTTCGGCAAGCCGATC
CTCAGATTTTTAATCAAAAGTTTAGAGACTATCAAAAAAAAACTGAGCAGGGGAAAGTGATTTTACTCAAAGAAAACTTT
CGTAGCCAATCAGAGGTGTTAAATGTCAGCAACGCTGTTTTTAGTCACTTAATGGACGAATCAGTAGGAGACGTCTTATA
TGATGAGCAACATCAGTTAATAGCAGGTAGTCATGCTCAAACAGTCCCCTATCTAGACCGTCGTGCTCAGTTATTGCTAT
ATAATAGCGATAAAGATGATGGCAACGCCCCTTCAGATAGTGAGGATATTTCATTTAGTGAGGTTACAATTGTTGCCAAA
GAAATTATTAAGCTTCACAATGATAAGGGTGTCCCTTTTGAAGACATTACGTTACTCGTTTCTTCAAGAACAAGAAATGA
TATCATTTCTCATACATTCAATCAATATGGTATTCCTATAGTAACAGATGGTGGGCAGCAAAACTATCTTAAATCTGTTG
AAGTGATGGTTATGTTAGATACATTACGCACCATTAATAACCCAAGAAATGATTATGCCCTTGTGGCTTTACTGCGCTCA
CCGATGTTTGCCTTTGATGAGGATGATTTAGCAAGAATAGCACTTCAAAAAGACAATGAGCTAGATAAAGATTGCCTATA
TGACAAGATACAAAGGGCTGTGATTGGAAGAGGTGCTTATCCTGAATTGATCCACGATACCTTGCTTGGCAAGTTAAATG
TTTTTTTAAAGACGTTGAAAAGCTGGCGTCGATACGCTAAGCTAGGGTCGTTGTATGACTTGATTTGGAAAATTTTCAAT
GATCGTTTTTATTTTGATTTTGTAGCTAGTCAAGCAAAAGCAGAACAAGCACAAGCTAATCTATACGCATTAGCTCTACG
TGCTAATCAGTTTGAAAAATCGGGCTATAAAGGGCTATACCGTTTTATTAAAATGATTGATAAGGTACTTGAGACGCAAA
ATGACTTAGCAGATGTGGAAGTGGCTGCTCCTAAACAAGCTGTTAATTTAATGACCATTCACAAGTCTAAAGGTTTACAA
TTTCCGTATGTATTTATCCTTAATTGTGACAAGCGCTTCTCAATGACGGATATTCATAAATCATTTATTCTGAATCGGCA
GCACGGTATCGGTATCAAGTACCTTGCAGATATCAAAGGTTTACTTGGTGAAACAACACTCAATTCTGTTAAAGTAAGCA
TGGAAACCTTACCTTATCAATTGAACAAACAAGAGTTGCGCTTAGCAACTTTATCAGAACAAATGCGCTTACTGTATGTT
GCTATGACACGAGCTGAAAAAAAAGTTTATTTTATTGGTAAAGCTAGTAAGAGCAAAAGTCAAGAAATCACAGATCCTAA
AAAGTTAGGCAAACTTTTGCCGCTGGCTTTACGAGAACAGTTATTGACATTCCAAGATTGGCTATTAGCAATAGCAGATA
TATTTTCAACTGAAGATCTTTATTTTGATGTTCGCTTTATTGAAGATAGTGATTTGACACAAGAGTCAGTCGGACGACTT
CAAACACCACAGTTATTAAATCCAGATGATCTTAAAGATAATCGTCAATCAGAAACAATTGCACGGGCTTTAGATATGTT
AGAAGCAGTGTCTCAATTGAATGCCAATTATGAAGCAGCTATTCATTTGCCAACAGTTCGAACGCCTAGCCAACTTAAGG
CAGCTTACGAGCCTTTATTAGAACCCATTGGTGTAGATATTATAGAGAAATCTTCTCGATCGCTATCTGATTTTACTTTG
CCACATTTTTCAAAAAAAGCAAAAGTTGAAGCAAGTCATATTGGATCAGCTCTTCATCAGTTGATGCAGGTGCTCCCTTT
GTCAAAACCGATAAATCAACAAACGCTTTTAGACGCTTTAAGAGGAATTGATAGTAACGAAGAGGTAAAAACAGCTCTTG
ATCTCAAAAAAATAGAGTCGTTCTTTTGTGATACAAGCCTAGGCCAATTTTTTCAGACTTACCAAAAACACTTGTATCGA
GAAGCACCATTTGCTATTTTAAAAGTTGACCCTATTAGTCAAGAAGAATATGTCCTACGTGGTATTATAGATGCCTACTT
TTTGTTTGATGATCATATTGTATTAGTGGACTATAAAACAGATAAATACAAGCAGCCCATTGAGTTAAAAAAGCGTTACC
AACAACAGTTGGAGTTATATGCAGAAGCTCTCACTCAAACGTATAAACTTCCTGTGACTAAGCGCTATCTTGTTTTAATG
GGAGGTGGAAAGCCAGAAATTGTCGAAGTTTAA

Domains

Predicted by InterProScan.

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(30-464)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1046-1197)

UvrD-like helicase C-terminal domain (UvrD_C)

(474-892)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

48.366

100

0.489

Multiple sequence alignment