Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   GL189_RS05495 Genome accession   NZ_CP046360
Coordinates   1094946..1095410 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain 574     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1089946..1100410
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL189_RS05475 (GL189_05600) - 1090897..1091865 (-) 969 WP_000105363.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  GL189_RS05480 (GL189_05605) pdrM 1092019..1093380 (-) 1362 WP_000278537.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  GL189_RS05485 (GL189_05610) - 1093391..1093651 (-) 261 WP_001105925.1 hypothetical protein -
  GL189_RS05490 (GL189_05615) - 1093665..1094933 (-) 1269 WP_000924503.1 dihydroorotase -
  GL189_RS05495 (GL189_05620) mutX 1094946..1095410 (-) 465 WP_001135768.1 NUDIX hydrolase Machinery gene
  GL189_RS05500 (GL189_05625) - 1095420..1096073 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  GL189_RS05505 (GL189_05630) - 1096211..1096858 (-) 648 WP_001813281.1 hypothetical protein -
  GL189_RS05510 (GL189_05635) - 1096872..1097585 (-) 714 WP_000499433.1 YjjG family noncanonical pyrimidine nucleotidase -
  GL189_RS05515 (GL189_05640) dhaM 1098043..1098423 (-) 381 WP_000443784.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  GL189_RS11290 - 1098423..1098497 (-) 75 Protein_1104 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=351349 GL189_RS05495 WP_001135768.1 1094946..1095410(-) (mutX) [Streptococcus pneumoniae strain 574]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=351349 GL189_RS05495 WP_001135768.1 1094946..1095410(-) (mutX) [Streptococcus pneumoniae strain 574]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGACGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987

Multiple sequence alignment