Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   GL188_RS06025 Genome accession   NZ_CP046359
Coordinates   1205746..1207035 (-) Length   429 a.a.
NCBI ID   WP_024477802.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 573     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1200746..1212035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL188_RS06010 (GL188_06125) - 1201159..1203324 (+) 2166 WP_000726258.1 ABC transporter substrate-binding protein/permease -
  GL188_RS06015 (GL188_06130) - 1203324..1204064 (+) 741 WP_001096316.1 amino acid ABC transporter ATP-binding protein -
  GL188_RS06020 (GL188_06135) zwf 1204213..1205700 (+) 1488 WP_000096145.1 glucose-6-phosphate dehydrogenase -
  GL188_RS06025 (GL188_06140) pilA 1205746..1207035 (-) 1290 WP_024477802.1 signal recognition particle-docking protein FtsY Machinery gene
  GL188_RS06030 (GL188_06145) - 1207039..1207857 (-) 819 WP_024477803.1 Cof-type HAD-IIB family hydrolase -
  GL188_RS06035 (GL188_06150) - 1207857..1208651 (-) 795 WP_000153040.1 Cof-type HAD-IIB family hydrolase -

Sequence

Protein


Download         Length: 429 a.a.        Molecular weight: 47869.96 Da        Isoelectric Point: 4.1714

>NTDB_id=351239 GL188_RS06025 WP_024477802.1 1205746..1207035(-) (pilA) [Streptococcus pneumoniae strain 573]
MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVDEVPQEEAEVEIVEQAVFQEEEIQDTVEESLDSEPVVGVS
QEEVEEFPHSEELPEEEKLDHEGTIEENNSEVLEAERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTT
SIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQ
NKDNLMAELEKIGRIIKRVVLEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPV
KLIGFGEKIDDIGEFNSENFMKGLLEGLI

Nucleotide


Download         Length: 1290 bp        

>NTDB_id=351239 GL188_RS06025 WP_024477802.1 1205746..1207035(-) (pilA) [Streptococcus pneumoniae strain 573]
ATGGGATTGTTTGACCGTCTATTCGGAAAAAAAGAAGAACCTAAAATCGAAGAAGTTGTAAAAGAAGCTCTGGAAAATCT
TGATTTGTCTGAAGATGTTGATCCTACCTTCACAGAAGTTGATGAAGTTCCTCAGGAAGAAGCAGAGGTTGAAATTGTTG
AACAAGCTGTGTTCCAAGAAGAGGAAATCCAAGACACAGTTGAAGAAAGTCTGGATTCAGAGCCAGTTGTAGGGGTTTCT
CAAGAAGAAGTCGAAGAATTTCCACACTCAGAAGAATTACCAGAGGAAGAGAAGCTTGATCACGAAGGAACTATAGAAGA
AAATAATTCTGAAGTTCTTGAAGCAGAAAGGCCTCAAGCAGAAGAAACCGTTCAGGAAAAATATGACCGCAGTCTTAAGA
AAACTCGCACAGGTTTCGGTGCCCGCTTGAATGCCTTCTTTGCTAACTTCCGCTCTGTTGACGAAGAATTTTTCGAGGAA
CTGGAAGAACTGCTGATTATGAGTGATGTTGGTGTCCAAGTCGCTTCTAACTTAACGGAGGAACTACGTTACGAAGCCAA
GCTTGAAAATGCCAAGAAACCTGATGCACTTCGTCGTGTCATCATTGAGAAATTGGTTGAGCTTTATGAAAAGGATGGTA
GCTACGATGAAAGCATCCACTTCCAAGATAACTTGACAGTTATGCTCTTTGTTGGTGTGAATGGTGTTGGGAAAACAACT
TCTATCGGAAAACTAGCCCACCGCTACAAACGAGCTGGTAAGAAGGTCATGCTGGTTGCAGCAGATACCTTCCGTGCGGG
TGCAGTAGCTCAGCTAGCTGAATGGGGCCGACGAGTAGATGTTCCAGTAGTAACTGGACCTGAAAAAGCTGATCCAGCCA
GCGTGGTCTTTGATGGTATGGAACGTGCCGTGGCTGAAGGTATCGATATTCTCATGATTGATACTGCTGGTCGTCTGCAA
AATAAGGATAACCTTATGGCTGAGTTGGAAAAGATTGGTCGTATTATCAAACGTGTTGTGCTAGAAGCACCACATGAAAC
CTTCTTGGCACTTGATGCATCAACAGGTCAAAATGCCCTAGTACAGGCCAAAGAATTTTCGAAAATCACACCTTTAACCG
GAATTGTTTTGACTAAGATTGATGGAACTGCTCGAGGAGGTGTGGTTCTAGCCATTCGTGAAGAACTCAATATTCCTGTA
AAATTGATTGGTTTTGGTGAAAAAATCGATGATATTGGAGAGTTTAACTCAGAAAACTTTATGAAAGGTCTCTTGGAAGG
TTTAATCTAA

Domains

Predicted by InterProScan.

SRP54-type protein, helical bundle domain (SRP54_N)

(139-205)

SRP54-type protein, GTPase domain (SRP54)

(226-425)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

35.845

100

0.366