Detailed information NTG0351149

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: GL186_RS09380
• Genome accession: NZ_CP046358
• Coordinates: 1838702..1839739 (-)
• Length: 345 a.a.
• NCBI ID: WP_000727276.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 566
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1833702..1844739

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL186_RS09355 (GL186_09520)	-	1834441..1835772 (-)	1332	WP_197097185.1	hemolysin family protein	-
GL186_RS09360 (GL186_09525)	endA	1836063..1836887 (-)	825	WP_001036786.1	DNA-entry nuclease EndA	Machinery gene
GL186_RS09365 (GL186_09530)	-	1836926..1837114 (-)	189	WP_001813390.1	DNA-directed RNA polymerase subunit beta	-
GL186_RS09370 (GL186_09535)	murA	1837107..1838390 (-)	1284	WP_000358028.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
GL186_RS09375 (GL186_09540)	-	1838414..1838644 (-)	231	WP_000250392.1	DUF1146 family protein	-
GL186_RS09380 (GL186_09545)	sepM	1838702..1839739 (-)	1038	WP_000727276.1	SepM family pheromone-processing serine protease	Regulator
GL186_RS09385 (GL186_09550)	coaD	1839723..1840211 (-)	489	WP_001280742.1	pantetheine-phosphate adenylyltransferase	-
GL186_RS09390 (GL186_09555)	rsmD	1840201..1840740 (-)	540	WP_000706962.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
GL186_RS09395 (GL186_09560)	asnA	1840805..1841797 (-)	993	WP_000747993.1	aspartate--ammonia ligase	-
GL186_RS09400 (GL186_09565)	-	1841909..1842592 (-)	684	WP_001016913.1	Bax inhibitor-1/YccA family protein	-
GL186_RS09405 (GL186_09570)	-	1842648..1843388 (-)	741	WP_000152701.1	TrmH family RNA methyltransferase	-
GL186_RS09410 (GL186_09575)	-	1843422..1843700 (+)	279	WP_001174613.1	acylphosphatase	-
GL186_RS09415 (GL186_09580)	yidC	1843778..1844704 (+)	927	WP_000835948.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37553.61 Da
• Isoelectric Point: 5.0724

>NTDB_id=351149 GL186_RS09380 WP_000727276.1 1838702..1839739(-) (sepM) [Streptococcus pneumoniae strain 566]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=351149 GL186_RS09380 WP_000727276.1 1838702..1839739(-) (sepM) [Streptococcus pneumoniae strain 566]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCGCAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTAAAGGGATTCTCAATATCTCTGATACAGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGATTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGCAAAAATGGAATTGGAATCGGCTTGATTGACCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCTGGACGCGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterProScan.

• PDZ domain (PDZ_2) (130-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.357	99.13	0.588