Detailed information NTG0351066

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GL186_RS00285
• Genome accession: NZ_CP046358
• Coordinates: 44917..45810 (+)
• Length: 297 a.a.
• NCBI ID: WP_000343888.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 566
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 39917..50810

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GL186_RS00255 (GL186_00255)	-	40230..41399 (+)	1170	WP_000366342.1	pyridoxal phosphate-dependent aminotransferase	-
GL186_RS00260 (GL186_00260)	recO	41396..42166 (+)	771	WP_000616164.1	DNA repair protein RecO	Machinery gene
GL186_RS00265 (GL186_00265)	plsX	42163..43155 (+)	993	WP_000717458.1	phosphate acyltransferase PlsX	-
GL186_RS00270 (GL186_00270)	-	43161..43394 (+)	234	WP_000136447.1	acyl carrier protein	-
GL186_RS00275 (GL186_00275)	-	43431..43730 (+)	300	Protein_47	transposase family protein	-
GL186_RS00280 (GL186_00280)	blpU	43933..44163 (+)	231	WP_001093487.1	bacteriocin-like peptide BlpU	-
GL186_RS11265	-	44166..44291 (+)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
GL186_RS10905	-	44702..44896 (+)	195	WP_000756776.1	hypothetical protein	-
GL186_RS00285 (GL186_00285)	comR	44917..45810 (+)	894	WP_000343888.1	helix-turn-helix domain-containing protein	Regulator
GL186_RS00290 (GL186_00290)	-	46353..46649 (+)	297	WP_000837726.1	uberolysin/carnocyclin family circular bacteriocin	-
GL186_RS00295 (GL186_00295)	-	46656..47792 (+)	1137	WP_000698828.1	hypothetical protein	-
GL186_RS00300 (GL186_00300)	-	47789..48271 (+)	483	WP_001232094.1	stage II sporulation protein M	-
GL186_RS00305 (GL186_00305)	-	48268..48864 (+)	597	WP_000687787.1	ATP-binding cassette domain-containing protein	-
GL186_RS00310 (GL186_00310)	-	48845..49336 (+)	492	WP_000671990.1	hypothetical protein	-

Sequence

Protein

• Length: 297 a.a.
• Molecular weight: 34517.01 Da
• Isoelectric Point: 4.6498

>NTDB_id=351066 GL186_RS00285 WP_000343888.1 44917..45810(+) (comR) [Streptococcus pneumoniae strain 566]
MDELKREIGYKIKTIRRSCGKTQIDICGDESELTIRQLARIENGQALATLPKLLLIADKLGVSLQNIVDVKVIEIPKGFL
KLKDELIHSQTYADKGRIERKEAILEEIYENYYENLPEEEQLIVDVTQARFDIYGSSDVTYGLGLVEEYFQQLLKKKYFS
VNDLLIIELYFFCCAMGLEDKEHFEELAQKVLLCSEYEDKASLVQMEKVLLSLFIQIQTEDSLIYIQTFEKIIAKTRHVF
YRPHLFLLKAKYALFVDKNILEAESFYEKAISLAELLDDQVLVQRILAEKQIDFPTT

Nucleotide

• Length: 894 bp

>NTDB_id=351066 GL186_RS00285 WP_000343888.1 44917..45810(+) (comR) [Streptococcus pneumoniae strain 566]
ATGGATGAGTTGAAACGTGAAATTGGTTATAAAATCAAAACTATTAGGCGATCTTGTGGAAAAACTCAGATAGATATTTG
TGGTGATGAATCAGAGTTGACGATTCGTCAGCTAGCACGTATTGAAAATGGGCAAGCTTTAGCAACACTTCCTAAATTAT
TATTGATTGCGGATAAACTTGGAGTATCATTACAGAATATTGTGGATGTTAAGGTTATAGAGATTCCAAAAGGATTCCTA
AAACTCAAAGATGAGCTGATTCATTCTCAAACCTACGCTGATAAGGGAAGAATCGAACGAAAAGAAGCTATACTTGAGGA
AATATATGAAAACTATTATGAGAATTTGCCTGAGGAAGAGCAGTTAATTGTGGATGTGACACAAGCTCGTTTTGATATTT
ATGGTAGTTCAGATGTGACCTACGGTTTAGGGTTAGTGGAAGAATATTTCCAGCAGTTATTAAAAAAGAAATATTTTTCT
GTAAATGATTTGTTGATTATTGAATTGTATTTCTTTTGTTGTGCTATGGGATTAGAAGATAAAGAACATTTTGAGGAGTT
AGCTCAAAAAGTATTGCTATGTTCAGAATATGAAGATAAGGCTAGCCTAGTTCAAATGGAAAAAGTTCTTCTGAGCCTAT
TTATCCAAATTCAGACAGAAGATAGTCTGATATATATTCAAACATTTGAGAAAATTATTGCTAAAACAAGACATGTTTTT
TACCGACCTCATCTATTTTTGCTAAAGGCAAAATATGCTTTATTTGTAGACAAGAATATTTTAGAGGCAGAAAGTTTCTA
TGAAAAGGCGATTTCTCTAGCAGAATTGCTAGACGATCAGGTATTAGTTCAGAGAATTTTAGCAGAAAAACAGATAGATT
TCCCAACAACCTGA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (76-289)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	36.667	100	0.37