Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   GL185_RS01480 Genome accession   NZ_CP046357
Coordinates   284304..285593 (+) Length   429 a.a.
NCBI ID   WP_024477802.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 525     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 279304..290593
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL185_RS01470 (GL185_01490) - 282688..283482 (+) 795 WP_000153040.1 HAD family hydrolase -
  GL185_RS01475 (GL185_01495) - 283482..284300 (+) 819 WP_024477803.1 Cof-type HAD-IIB family hydrolase -
  GL185_RS01480 (GL185_01500) pilA 284304..285593 (+) 1290 WP_024477802.1 signal recognition particle-docking protein FtsY Machinery gene
  GL185_RS01485 (GL185_01505) zwf 285639..287126 (-) 1488 WP_024477801.1 glucose-6-phosphate dehydrogenase -
  GL185_RS01490 (GL185_01510) - 287275..288015 (-) 741 WP_001096313.1 amino acid ABC transporter ATP-binding protein -
  GL185_RS01495 (GL185_01515) - 288015..290180 (-) 2166 WP_000726272.1 ABC transporter substrate-binding protein/permease -

Sequence

Protein


Download         Length: 429 a.a.        Molecular weight: 47869.96 Da        Isoelectric Point: 4.1714

>NTDB_id=350951 GL185_RS01480 WP_024477802.1 284304..285593(+) (pilA) [Streptococcus pneumoniae strain 525]
MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDPTFTEVDEVPQEEAEVEIVEQAVFQEEEIQDTVEESLDSEPVVGVS
QEEVEEFPHSEELPEEEKLDHEGTIEENNSEVLEAERPQAEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDALRRVIIEKLVELYEKDGSYDESIHFQDNLTVMLFVGVNGVGKTT
SIGKLAHRYKRAGKKVMLVAADTFRAGAVAQLAEWGRRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQ
NKDNLMAELEKIGRIIKRVVLEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAIREELNIPV
KLIGFGEKIDDIGEFNSENFMKGLLEGLI

Nucleotide


Download         Length: 1290 bp        

>NTDB_id=350951 GL185_RS01480 WP_024477802.1 284304..285593(+) (pilA) [Streptococcus pneumoniae strain 525]
ATGGGATTGTTTGACCGTCTATTCGGAAAAAAAGAAGAACCTAAAATCGAAGAAGTTGTAAAAGAAGCTCTGGAAAATCT
TGATTTGTCTGAAGATGTTGATCCTACCTTCACAGAAGTTGATGAAGTTCCTCAGGAAGAAGCAGAGGTTGAAATTGTTG
AACAAGCTGTGTTCCAAGAAGAGGAAATCCAAGACACAGTTGAAGAAAGTCTGGATTCAGAGCCAGTTGTAGGGGTTTCT
CAAGAAGAAGTCGAAGAATTTCCACACTCAGAAGAATTACCAGAGGAAGAGAAGCTTGATCACGAAGGAACTATAGAAGA
AAATAATTCTGAAGTTCTTGAAGCAGAAAGGCCTCAAGCAGAAGAAACCGTTCAGGAAAAATATGACCGCAGTCTTAAGA
AAACTCGCACAGGTTTCGGTGCCCGCTTGAATGCCTTCTTTGCTAACTTCCGCTCTGTTGACGAAGAATTTTTCGAGGAA
CTGGAAGAACTGCTGATTATGAGTGATGTTGGTGTCCAAGTCGCTTCTAACTTAACGGAGGAACTACGTTACGAAGCCAA
GCTTGAAAATGCCAAGAAACCTGATGCACTTCGTCGTGTCATCATTGAGAAATTGGTTGAGCTTTATGAAAAGGATGGTA
GCTACGATGAAAGCATCCACTTCCAAGATAACTTGACAGTTATGCTCTTTGTTGGTGTGAATGGTGTTGGGAAAACAACT
TCTATCGGAAAACTAGCCCACCGCTACAAACGAGCTGGTAAGAAGGTCATGCTGGTTGCAGCAGATACCTTCCGTGCGGG
TGCAGTAGCTCAGCTAGCTGAATGGGGCCGACGAGTAGATGTTCCAGTAGTAACTGGACCTGAAAAAGCTGATCCAGCCA
GCGTGGTCTTTGATGGTATGGAACGTGCCGTGGCTGAAGGTATCGATATTCTCATGATTGATACTGCTGGTCGTCTGCAA
AATAAGGATAACCTTATGGCTGAGTTGGAAAAGATTGGTCGTATTATCAAACGTGTTGTGCTAGAAGCACCACATGAAAC
CTTCTTGGCACTTGATGCATCAACAGGTCAAAATGCCCTAGTACAGGCCAAAGAATTTTCGAAAATCACACCTTTAACCG
GAATTGTTTTGACTAAGATTGATGGAACTGCTCGAGGAGGTGTGGTTCTAGCCATTCGTGAAGAACTCAATATTCCTGTA
AAATTGATTGGTTTTGGTGAAAAAATCGATGATATTGGAGAGTTTAACTCAGAAAACTTTATGAAAGGTCTCTTGGAAGG
TTTAATCTAA

Domains

Predicted by InterProScan.

SRP54-type protein, helical bundle domain (SRP54_N)

(139-205)

SRP54-type protein, GTPase domain (SRP54)

(226-425)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

35.845

100

0.366

Multiple sequence alignment