Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   GL184_RS05235 Genome accession   NZ_CP046356
Coordinates   999436..999900 (+) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain 521     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 994436..1004900
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GL184_RS11575 - 996349..996423 (+) 75 Protein_983 dihydroxyacetone kinase subunit L -
  GL184_RS05215 (GL184_05265) dhaM 996423..996803 (+) 381 WP_000443784.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  GL184_RS05220 (GL184_05270) - 997261..997974 (+) 714 WP_000499433.1 YjjG family noncanonical pyrimidine nucleotidase -
  GL184_RS05225 (GL184_05275) - 997988..998635 (+) 648 WP_001813281.1 hypothetical protein -
  GL184_RS05230 (GL184_05280) - 998773..999426 (+) 654 WP_000401326.1 uracil-DNA glycosylase -
  GL184_RS05235 (GL184_05285) mutX 999436..999900 (+) 465 WP_001135768.1 NUDIX hydrolase Machinery gene
  GL184_RS05240 (GL184_05290) - 999913..1001181 (+) 1269 WP_000924503.1 dihydroorotase -
  GL184_RS05245 (GL184_05295) - 1001195..1001455 (+) 261 WP_001105925.1 hypothetical protein -
  GL184_RS05250 (GL184_05300) pdrM 1001466..1002827 (+) 1362 WP_000278537.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  GL184_RS05255 (GL184_05305) - 1002981..1003949 (+) 969 WP_000105363.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=350894 GL184_RS05235 WP_001135768.1 999436..999900(+) (mutX) [Streptococcus pneumoniae strain 521]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=350894 GL184_RS05235 WP_001135768.1 999436..999900(+) (mutX) [Streptococcus pneumoniae strain 521]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGACGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987