Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   MGAS15252_RS03715 Genome accession   NC_017040
Coordinates   744730..745206 (+) Length   158 a.a.
NCBI ID   WP_010922230.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS15252     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 739730..750206
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS15252_RS03690 (MGAS15252_0761) - 739771..740559 (+) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -
  MGAS15252_RS03695 (MGAS15252_0762) - 740599..741705 (+) 1107 WP_014407520.1 NAD(P)/FAD-dependent oxidoreductase -
  MGAS15252_RS03700 (MGAS15252_0763) rfbA 741763..742632 (+) 870 WP_014407521.1 glucose-1-phosphate thymidylyltransferase RfbA -
  MGAS15252_RS03705 (MGAS15252_0764) - 742632..743225 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  MGAS15252_RS03710 (MGAS15252_0765) rfbB 743469..744509 (+) 1041 WP_014407522.1 dTDP-glucose 4,6-dehydratase -
  MGAS15252_RS03715 (MGAS15252_0766) mutX 744730..745206 (+) 477 WP_010922230.1 NUDIX hydrolase Machinery gene
  MGAS15252_RS03720 (MGAS15252_0767) - 745264..746445 (+) 1182 WP_002990002.1 AI-2E family transporter -
  MGAS15252_RS03725 (MGAS15252_0768) - 746435..747682 (+) 1248 WP_014407523.1 tetratricopeptide repeat protein -
  MGAS15252_RS03730 (MGAS15252_0769) fbp54 747741..749393 (-) 1653 WP_014407524.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18452.64 Da        Isoelectric Point: 4.3268

>NTDB_id=35047 MGAS15252_RS03715 WP_010922230.1 744730..745206(+) (mutX) [Streptococcus pyogenes MGAS15252]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRSFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=35047 MGAS15252_RS03715 WP_010922230.1 744730..745206(+) (mutX) [Streptococcus pyogenes MGAS15252]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCAGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTTCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

69.62

100

0.696

Multiple sequence alignment