Detailed information NTG0350150

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: GKC13_RS02055
• Genome accession: NZ_CP046134
• Coordinates: 381863..383962 (+)
• Length: 699 a.a.
• NCBI ID: WP_207560117.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain MAG_rmk202_sterm
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 376863..388962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GKC13_RS02025 (GKC13_02025)	yhbY	376968..377285 (+)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-
GKC13_RS02030 (GKC13_02030)	-	377389..378021 (+)	633	WP_002951698.1	nicotinate-nucleotide adenylyltransferase	-
GKC13_RS02035 (GKC13_02035)	yqeK	378018..378608 (+)	591	WP_002951696.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
GKC13_RS02040 (GKC13_02040)	rsfS	378632..378985 (+)	354	WP_011227491.1	ribosome silencing factor	-
GKC13_RS02045 (GKC13_02045)	-	379310..380050 (+)	741	WP_277426406.1	class I SAM-dependent methyltransferase	-
GKC13_RS02050 (GKC13_02050)	-	380057..381148 (+)	1092	WP_207560116.1	nucleotidyltransferase	-
GKC13_RS02055 (GKC13_02055)	clpE	381863..383962 (+)	2100	WP_207560117.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
GKC13_RS10350	-	384371..384496 (+)	126	WP_011681534.1	hypothetical protein	-
GKC13_RS02060 (GKC13_02060)	-	384515..385150 (+)	636	WP_179971026.1	DUF4230 domain-containing protein	-
GKC13_RS09865	-	385220..385390 (+)	171	WP_011226439.1	hypothetical protein	-
GKC13_RS02070 (GKC13_02070)	-	385942..386250 (-)	309	WP_179971427.1	hypothetical protein	-
GKC13_RS02075 (GKC13_02075)	-	386247..386666 (-)	420	WP_002951675.1	HIT family protein	-
GKC13_RS02080 (GKC13_02080)	pptA	386731..387462 (+)	732	WP_002951673.1	ABC transporter ATP-binding protein	Regulator
GKC13_RS02085 (GKC13_02085)	pptB	387459..388496 (+)	1038	WP_179971023.1	ABC transporter permease	Regulator

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77148.01 Da
• Isoelectric Point: 4.8556

>NTDB_id=350150 GKC13_RS02055 WP_207560117.1 381863..383962(+) (clpE) [Streptococcus thermophilus strain MAG_rmk202_sterm]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQIIGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQHPV
TDVNAVEHEIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGATDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKNAK

Nucleotide

• Length: 2100 bp

>NTDB_id=350150 GKC13_RS02055 WP_207560117.1 381863..383962(+) (clpE) [Streptococcus thermophilus strain MAG_rmk202_sterm]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACGCAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTTGGCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGCAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTATTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACATGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTGGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAAATGCTAAATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (439-599)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (606-676)

• AAA lid domain (AAA_lid_9) (255-349)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-246)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.866	100	0.471
clpC	Lactococcus lactis subsp. cremoris KW2	48.906	91.559	0.448
clpE	Streptococcus pneumoniae TIGR4	48.657	90.558	0.441
clpE	Streptococcus pneumoniae Rx1	48.657	90.558	0.441
clpE	Streptococcus pneumoniae D39	48.657	90.558	0.441
clpE	Streptococcus pneumoniae R6	48.657	90.558	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	46.285	92.418	0.428
clpC	Streptococcus thermophilus LMD-9	43.417	91.273	0.396
clpC	Streptococcus thermophilus LMG 18311	43.26	91.273	0.395
clpC	Streptococcus pneumoniae TIGR4	43.339	89.127	0.386
clpC	Streptococcus pneumoniae Rx1	43.339	89.127	0.386
clpC	Streptococcus pneumoniae D39	43.339	89.127	0.386
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.436	88.269	0.383
clpC	Streptococcus mutans UA159	42.788	89.27	0.382