Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiE   Type   Regulator
Locus tag   EZ612_RS01365 Genome accession   NZ_CP036531
Coordinates   259984..261054 (+) Length   356 a.a.
NCBI ID   WP_010921893.1    Uniprot ID   A0A4U9C068
Organism   Streptococcus pyogenes strain STAB10048     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 254984..266054
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EZ612_RS01350 (EZ612_01365) amiA 255512..257482 (+) 1971 WP_024623426.1 peptide ABC transporter substrate-binding protein Regulator
  EZ612_RS01355 (EZ612_01370) amiC 257547..259049 (+) 1503 WP_002991105.1 ABC transporter permease Regulator
  EZ612_RS01360 (EZ612_01375) amiD 259049..259975 (+) 927 WP_002986004.1 oligopeptide ABC transporter permease OppC Regulator
  EZ612_RS01365 (EZ612_01380) amiE 259984..261054 (+) 1071 WP_010921893.1 ABC transporter ATP-binding protein Regulator
  EZ612_RS01370 (EZ612_01385) amiF 261047..261970 (+) 924 WP_002986000.1 ABC transporter ATP-binding protein Regulator
  EZ612_RS08875 - 261906..262097 (-) 192 WP_367849538.1 IS3 family transposase -
  EZ612_RS01375 (EZ612_01390) - 262118..262297 (-) 180 WP_023612403.1 hypothetical protein -

Sequence

Protein


Download         Length: 356 a.a.        Molecular weight: 39703.77 Da        Isoelectric Point: 5.6707

>NTDB_id=349452 EZ612_RS01365 WP_010921893.1 259984..261054(+) (amiE) [Streptococcus pyogenes strain STAB10048]
MTKENNVILTAKDVVVEFDVRDRVLTAIRNVSLELVEGEVLAFVGESGSGKSVLTKTFTGMLESNGRIANGSIVYRGQEL
TDLKTNKEWAKIRGSKIATIFQDPMTSLSPIKTIGSQITEVIIKHQKVSHAKAKEMALDYMNKVGIPNAKKRFEDYPFEY
SGGMRQRIVIAIALACRPDILICDEPTTALDVTIQAQIVELLKSLQREYHFTIIFITHDLGVVASIADKVAVMYAGEIVE
FGTVEEIFYDPRHPYTWSLLSSLPQLADESGELYAIPGTPPSLYSPIIGDAFALRSEYAMVLDFEKAPPAINVSETHWAK
TWLLHPEAPKVQKPEVIQDLHQKILRKMSQQEEGNV

Nucleotide


Download         Length: 1071 bp        

>NTDB_id=349452 EZ612_RS01365 WP_010921893.1 259984..261054(+) (amiE) [Streptococcus pyogenes strain STAB10048]
ATGACAAAAGAAAATAATGTAATCTTAACTGCCAAAGATGTGGTGGTAGAATTTGATGTGCGTGATCGTGTTTTAACAGC
TATCCGTAACGTCTCACTGGAACTTGTTGAAGGAGAAGTCCTTGCTTTTGTAGGGGAATCAGGCTCAGGTAAATCTGTTT
TAACAAAGACCTTTACAGGGATGTTGGAGTCTAATGGACGCATTGCTAATGGTTCAATTGTCTATCGTGGGCAAGAATTG
ACAGATTTAAAAACAAATAAAGAGTGGGCAAAGATTCGCGGCTCAAAAATCGCAACGATTTTCCAAGACCCAATGACCAG
TCTTAGTCCCATTAAAACTATCGGTAGCCAAATCACAGAAGTGATTATTAAGCACCAAAAAGTAAGTCATGCCAAAGCTA
AAGAAATGGCCCTTGATTACATGAATAAAGTGGGTATCCCAAATGCCAAAAAACGCTTTGAAGATTACCCATTTGAGTAT
TCAGGAGGAATGCGTCAACGTATTGTTATCGCTATTGCTTTAGCTTGTCGTCCAGATATTCTTATCTGTGATGAGCCAAC
AACAGCCCTTGATGTGACTATTCAAGCTCAAATCGTTGAGTTATTGAAGTCGCTTCAACGAGAATATCATTTCACCATTA
TCTTTATTACGCACGATTTAGGTGTTGTGGCAAGCATTGCAGATAAAGTGGCTGTCATGTATGCAGGAGAAATTGTTGAA
TTTGGAACAGTCGAAGAGATTTTCTATGATCCAAGACACCCCTATACATGGAGTTTGCTGTCTAGCTTACCGCAGTTGGC
AGATGAATCTGGTGAACTTTACGCTATTCCAGGAACGCCTCCATCACTTTATTCACCAATTATCGGAGATGCCTTTGCAC
TTCGCTCAGAATATGCTATGGTTTTAGACTTTGAAAAAGCACCTCCGGCGATTAACGTATCTGAGACTCATTGGGCCAAA
ACATGGCTTTTACACCCAGAGGCTCCAAAAGTTCAAAAACCAGAAGTCATTCAAGATTTGCATCAAAAAATCTTAAGGAA
AATGTCACAACAGGAGGAAGGAAATGTCTGA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(29-187)

Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY)

(239-299)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9C068

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiE Streptococcus salivarius strain HSISS4

76.667

100

0.775
  amiE Streptococcus thermophilus LMG 18311

75.556

100

0.764
  amiE Streptococcus thermophilus LMD-9

75.556

100

0.764
  oppD Streptococcus mutans UA159

56.677

94.663

0.537

Multiple sequence alignment