Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | EZ612_RS01110 | Genome accession | NZ_CP036531 |
| Coordinates | 203469..204830 (+) | Length | 453 a.a. |
| NCBI ID | WP_002986109.1 | Uniprot ID | A0A4Q1R665 |
| Organism | Streptococcus pyogenes strain STAB10048 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 167878..203388 | 203469..204830 | flank | 81 |
Gene organization within MGE regions
Location: 167878..204830
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EZ612_RS00940 (EZ612_00955) | - | 167878..169074 (+) | 1197 | WP_002986345.1 | quaternary amine ABC transporter ATP-binding protein | - |
| EZ612_RS00945 (EZ612_00960) | - | 169090..170817 (+) | 1728 | WP_011528204.1 | ABC transporter permease/substrate binding protein | - |
| EZ612_RS00950 (EZ612_00965) | polA | 170948..173590 (+) | 2643 | WP_031488641.1 | DNA polymerase I | - |
| EZ612_RS00955 (EZ612_00970) | - | 173768..174223 (+) | 456 | WP_031488640.1 | CoA-binding protein | - |
| EZ612_RS00960 (EZ612_00975) | perR | 174275..174742 (+) | 468 | WP_031488639.1 | peroxide-responsive transcriptional repressor PerR | - |
| EZ612_RS00965 (EZ612_00980) | - | 174961..175197 (+) | 237 | WP_014635252.1 | hypothetical protein | - |
| EZ612_RS00970 (EZ612_00985) | - | 175419..176753 (+) | 1335 | WP_031488638.1 | phosphoadenosine phosphosulfate reductase | - |
| EZ612_RS00975 (EZ612_00990) | - | 176746..177276 (+) | 531 | WP_002987925.1 | IbrB-like domain-containing protein | - |
| EZ612_RS08530 | - | 177323..177472 (-) | 150 | Protein_158 | ISL3 family transposase | - |
| EZ612_RS00985 (EZ612_01000) | - | 177604..178754 (-) | 1151 | Protein_159 | IS3 family transposase | - |
| EZ612_RS00995 (EZ612_01010) | - | 178832..180142 (-) | 1311 | WP_031488784.1 | SLC13 family permease | - |
| EZ612_RS01000 (EZ612_01015) | nadC | 180366..181238 (+) | 873 | WP_031488783.1 | carboxylating nicotinate-nucleotide diphosphorylase | - |
| EZ612_RS01010 (EZ612_01025) | - | 182966..183829 (-) | 864 | WP_031488685.1 | DUF975 family protein | - |
| EZ612_RS08815 (EZ612_01030) | - | 183866..184051 (+) | 186 | WP_002986321.1 | hypothetical protein | - |
| EZ612_RS01020 (EZ612_01035) | tgt | 184048..185190 (+) | 1143 | WP_031488684.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| EZ612_RS01025 (EZ612_01040) | - | 185408..185719 (+) | 312 | WP_002987947.1 | CHY zinc finger protein | - |
| EZ612_RS01030 (EZ612_01045) | - | 185723..186262 (+) | 540 | WP_002986314.1 | biotin transporter BioY | - |
| EZ612_RS01035 (EZ612_01050) | - | 186402..187181 (+) | 780 | WP_011528209.1 | MBL fold metallo-hydrolase | - |
| EZ612_RS01040 (EZ612_01055) | tadA | 187181..187696 (+) | 516 | WP_002992549.1 | tRNA adenosine(34) deaminase TadA | - |
| EZ612_RS01045 (EZ612_01060) | - | 188310..189542 (-) | 1233 | WP_031488683.1 | transglutaminase domain-containing protein | - |
| EZ612_RS01055 (EZ612_01070) | speG | 189942..190646 (+) | 705 | WP_031488682.1 | streptococcal pyrogenic exotoxin SpeG | - |
| EZ612_RS01060 (EZ612_01075) | - | 191102..192451 (+) | 1350 | WP_014635263.1 | glucose-6-phosphate isomerase | - |
| EZ612_RS01065 (EZ612_01080) | - | 192800..194308 (-) | 1509 | WP_002986134.1 | helix-turn-helix domain-containing protein | - |
| EZ612_RS01070 (EZ612_01085) | - | 194996..195667 (+) | 672 | WP_031488681.1 | rhomboid family intramembrane serine protease | - |
| EZ612_RS01075 (EZ612_01090) | galU | 195766..196665 (-) | 900 | WP_002986125.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| EZ612_RS01080 (EZ612_01095) | - | 196698..197714 (-) | 1017 | WP_002986123.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| EZ612_RS01085 (EZ612_01100) | - | 198012..198461 (+) | 450 | WP_002986120.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| EZ612_RS01090 (EZ612_01105) | - | 198454..200160 (+) | 1707 | WP_031488680.1 | ABC transporter ATP-binding protein | - |
| EZ612_RS01095 (EZ612_01110) | - | 200163..201947 (+) | 1785 | WP_023610145.1 | ABC transporter ATP-binding protein | - |
| EZ612_RS01100 (EZ612_01115) | - | 202065..202832 (+) | 768 | WP_011054158.1 | epoxyqueuosine reductase QueH | - |
| EZ612_RS01105 (EZ612_01120) | - | 202942..203388 (+) | 447 | WP_002986111.1 | dUTP diphosphatase | - |
| EZ612_RS01110 (EZ612_01125) | radA | 203469..204830 (+) | 1362 | WP_002986109.1 | DNA repair protein RadA | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49386.68 Da Isoelectric Point: 6.0962
>NTDB_id=349447 EZ612_RS01110 WP_002986109.1 203469..204830(+) (radA) [Streptococcus pyogenes strain STAB10048]
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGTVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
Nucleotide
Download Length: 1362 bp
>NTDB_id=349447 EZ612_RS01110 WP_002986109.1 203469..204830(+) (radA) [Streptococcus pyogenes strain STAB10048]
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAATATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCGGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAATATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATCGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGATTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAATATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCGGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGAACGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGCACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAATATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGGCCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATCGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGATTTACCAAGGTCTATGCTCCTAAAAATGCCTT
GCAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
85.872 |
100 |
0.859 |
| radA | Streptococcus pneumoniae D39 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae R6 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae Rx1 |
85.651 |
100 |
0.857 |
| radA | Streptococcus mitis SK321 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae TIGR4 |
85.651 |
100 |
0.857 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
61.369 |
100 |
0.614 |