Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EYB46_RS04525 Genome accession   NZ_CP036518
Coordinates   1016334..1016990 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain ANSB01E     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1011334..1021990
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EYB46_RS04510 (EYB46_04505) spxH 1011573..1012475 (+) 903 WP_032874464.1 protease adaptor protein SpxH -
  EYB46_RS19680 - 1012761..1012928 (+) 168 WP_032874462.1 hypothetical protein -
  EYB46_RS04515 (EYB46_04510) pepF 1012966..1014795 (-) 1830 WP_087920792.1 oligoendopeptidase F Regulator
  EYB46_RS04520 (EYB46_04515) - 1015023..1016183 (-) 1161 WP_032874460.1 competence protein CoiA family protein -
  EYB46_RS04525 (EYB46_04520) mecA 1016334..1016990 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  EYB46_RS19775 - 1016973..1017083 (-) 111 Protein_899 adaptor protein MecA -
  EYB46_RS04530 (EYB46_04525) - 1017266..1017922 (+) 657 WP_032874459.1 TerC family protein -
  EYB46_RS04535 (EYB46_04530) spx 1017979..1018374 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  EYB46_RS04540 (EYB46_04535) - 1018553..1019131 (-) 579 WP_032874457.1 GNAT family N-acetyltransferase -
  EYB46_RS04545 (EYB46_04540) - 1019249..1020436 (-) 1188 WP_079891125.1 putative glycoside hydrolase -
  EYB46_RS04550 (EYB46_04545) oppF 1020543..1021460 (-) 918 WP_017417453.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=349288 EYB46_RS04525 WP_003155032.1 1016334..1016990(-) (mecA) [Bacillus velezensis strain ANSB01E]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=349288 EYB46_RS04525 WP_003155032.1 1016334..1016990(-) (mecA) [Bacillus velezensis strain ANSB01E]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAGA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment