Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   EZZ25_RS04120 Genome accession   NZ_CP036499
Coordinates   852485..853600 (+) Length   371 a.a.
NCBI ID   WP_000654777.1    Uniprot ID   -
Organism   Vibrio cholerae strain 20000     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 847485..858600
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EZZ25_RS04100 (EZZ25_04100) rsmB 848408..849688 (-) 1281 WP_001102806.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  EZZ25_RS04105 (EZZ25_04105) fmt 849744..850691 (-) 948 WP_000083534.1 methionyl-tRNA formyltransferase -
  EZZ25_RS04110 (EZZ25_04110) def 850709..851218 (-) 510 WP_000115010.1 peptide deformylase -
  EZZ25_RS04115 (EZZ25_04115) - 851358..852485 (+) 1128 WP_000113377.1 LysM peptidoglycan-binding domain-containing protein -
  EZZ25_RS04120 (EZZ25_04120) dprA 852485..853600 (+) 1116 WP_000654777.1 DNA-processing protein DprA Machinery gene
  EZZ25_RS04125 (EZZ25_04125) - 853603..854079 (+) 477 WP_000979769.1 DUF494 family protein -
  EZZ25_RS04130 (EZZ25_04130) - 854095..854661 (+) 567 WP_000087523.1 type I DNA topoisomerase -
  EZZ25_RS04135 (EZZ25_04135) - 854734..855867 (-) 1134 WP_001265401.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  EZZ25_RS04140 (EZZ25_04140) purE 855871..856356 (-) 486 WP_000215771.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  EZZ25_RS04145 (EZZ25_04145) - 856523..857080 (+) 558 WP_002045789.1 L-threonylcarbamoyladenylate synthase -
  EZZ25_RS04150 (EZZ25_04150) hemF 857099..858016 (+) 918 WP_000443977.1 oxygen-dependent coproporphyrinogen oxidase -

Sequence

Protein


Download         Length: 371 a.a.        Molecular weight: 39978.98 Da        Isoelectric Point: 7.1952

>NTDB_id=349221 EZZ25_RS04120 WP_000654777.1 852485..853600(+) (dprA) [Vibrio cholerae strain 20000]
MKDQDLAAWLALCFTPKLGSKTISHLLATRLPAQLQSFTPKQWLASGLKPEQLVFLTTQAAKQAELCLQWRSAANNRYIV
TPHCPLYPRLLKEISSSPPILFIEGIWEAVHDPAVAIVGSRNASVDGRQIARQFATELAQSGLVVTSGLALGIDGYAHDG
ALQAQGQTVAVLGSGLAQVYPKQHQGLAERIMAQGALVSEFAPHTPPKADHFPRRNRIISGLSLGVVVVEAAEKSGSLIT
ARYAAEQGREVFVVPGSIFNAASQGSNQLIRQGACLVQSVQQIHQELKNALTWSLSEQVPYQATLFSAVQGDEELPFPEL
LANVGIEATPIDILASRTQIPVQDIMMQLLELELLGHVVAVPGGYIRKGRG

Nucleotide


Download         Length: 1116 bp        

>NTDB_id=349221 EZZ25_RS04120 WP_000654777.1 852485..853600(+) (dprA) [Vibrio cholerae strain 20000]
ATGAAAGATCAGGATTTAGCGGCATGGTTGGCGCTCTGTTTTACTCCTAAACTAGGCAGCAAAACCATTTCTCACCTGCT
TGCGACCCGTTTGCCAGCCCAGTTGCAAAGTTTTACGCCTAAGCAATGGTTGGCCAGCGGGCTTAAGCCCGAACAACTGG
TGTTTTTAACCACTCAAGCGGCTAAGCAAGCCGAGCTGTGTTTGCAATGGCGATCAGCAGCCAATAACCGCTATATCGTC
ACTCCTCATTGCCCGCTTTACCCTCGTTTATTGAAAGAGATTAGCTCATCGCCTCCCATCCTGTTTATCGAAGGAATATG
GGAAGCGGTGCATGACCCTGCGGTGGCTATCGTCGGTAGCCGCAATGCCAGTGTTGATGGGCGGCAGATCGCTCGCCAGT
TTGCCACTGAGCTCGCGCAGTCGGGTTTAGTGGTCACCAGTGGTTTAGCGCTTGGTATAGACGGCTATGCGCACGATGGA
GCTTTGCAAGCACAAGGGCAAACCGTGGCAGTATTAGGCTCAGGGCTGGCGCAGGTTTACCCCAAACAGCATCAAGGATT
AGCGGAGCGAATCATGGCCCAAGGGGCCTTGGTTTCTGAGTTTGCCCCTCACACACCGCCTAAAGCCGATCACTTTCCGC
GCCGTAACCGAATTATCAGCGGCTTATCGCTGGGCGTTGTGGTGGTAGAAGCTGCGGAGAAAAGCGGCTCACTCATCACT
GCGCGCTACGCCGCTGAGCAAGGGCGTGAGGTCTTTGTGGTTCCCGGCTCGATTTTTAATGCCGCCAGCCAAGGTAGCAA
TCAATTGATTCGTCAAGGCGCTTGTTTGGTGCAAAGTGTGCAACAAATTCATCAAGAGCTCAAAAATGCGCTGACTTGGT
CACTCTCTGAACAAGTTCCTTATCAAGCAACACTTTTTTCTGCTGTACAGGGTGATGAAGAATTGCCATTTCCCGAGCTG
TTAGCTAACGTAGGAATAGAAGCTACACCTATTGATATTCTCGCAAGCCGGACCCAGATACCGGTGCAAGATATCATGAT
GCAGCTCTTGGAGCTTGAGCTCCTTGGGCATGTGGTTGCAGTACCTGGTGGCTATATTAGAAAGGGGAGAGGCTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(77-278)

DprA winged helix domain (DprA_WH)

(319-364)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio cholerae strain A1552

98.383

100

0.984
  dprA Vibrio campbellii strain DS40M4

58.108

99.73

0.58
  dprA Legionella pneumophila strain ERS1305867

43.583

100

0.439
  dprA Glaesserella parasuis strain SC1401

43.351

100

0.439
  dprA Neisseria meningitidis strain C311

37.594

100

0.404
  dprA Neisseria meningitidis MC58

37.594

100

0.404
  dprA Neisseria gonorrhoeae strain FA1090

36.776

100

0.394
  dprA Acinetobacter baumannii D1279779

43.505

89.218

0.388
  dprA Acinetobacter baumannii strain A118

43.202

89.218

0.385
  dprA Neisseria gonorrhoeae MS11

35.949

100

0.383
  dprA Acinetobacter baylyi ADP1

42.042

89.757

0.377
  dprA Haemophilus influenzae Rd KW20

48.387

75.202

0.364

Multiple sequence alignment