Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   GJE16_RS05395 Genome accession   NZ_CP045931
Coordinates   1066854..1067318 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain AUSMDU00010538     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1061854..1072318
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GJE16_RS05375 (GJE16_05375) - 1062805..1063773 (-) 969 WP_000105363.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  GJE16_RS05380 (GJE16_05380) pdrM 1063927..1065288 (-) 1362 WP_000278526.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  GJE16_RS05385 (GJE16_05385) - 1065299..1065559 (-) 261 WP_001105925.1 hypothetical protein -
  GJE16_RS05390 (GJE16_05390) - 1065573..1066841 (-) 1269 WP_000924508.1 dihydroorotase -
  GJE16_RS05395 (GJE16_05395) mutX 1066854..1067318 (-) 465 WP_001135768.1 NUDIX hydrolase Machinery gene
  GJE16_RS05400 (GJE16_05400) - 1067328..1067981 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  GJE16_RS05405 (GJE16_05405) - 1068119..1068766 (-) 648 WP_001813281.1 hypothetical protein -
  GJE16_RS05410 (GJE16_05410) - 1068780..1069493 (-) 714 WP_000499432.1 YjjG family noncanonical pyrimidine nucleotidase -
  GJE16_RS05415 (GJE16_05415) dhaM 1069953..1070333 (-) 381 WP_000443785.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  GJE16_RS11435 - 1070333..1070407 (-) 75 Protein_1068 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=348823 GJE16_RS05395 WP_001135768.1 1066854..1067318(-) (mutX) [Streptococcus pneumoniae strain AUSMDU00010538]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=348823 GJE16_RS05395 WP_001135768.1 1066854..1067318(-) (mutX) [Streptococcus pneumoniae strain AUSMDU00010538]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987