Detailed information NTG0348281

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: EXA24_RS02955
• Genome accession: NZ_CP036376
• Coordinates: 531847..534108 (-)
• Length: 753 a.a.
• NCBI ID: WP_000882548.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain Sag153
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 526847..539108

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EXA24_RS02935 (EXA24_03025)	-	526876..527646 (+)	771	WP_001131467.1	DivIVA domain-containing protein	-
EXA24_RS02940 (EXA24_03030)	ileS	527931..530723 (+)	2793	WP_000768155.1	isoleucine--tRNA ligase	-
EXA24_RS02945 (EXA24_03035)	-	530840..531142 (-)	303	WP_001237035.1	DUF1827 family protein	-
EXA24_RS02950 (EXA24_03040)	-	531206..531661 (-)	456	WP_000184290.1	NUDIX hydrolase	-
EXA24_RS02955 (EXA24_03045)	clpE	531847..534108 (-)	2262	WP_000882548.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
EXA24_RS02960 (EXA24_03055)	-	534406..534636 (+)	231	WP_000443582.1	DUF1797 family protein	-
EXA24_RS02965 (EXA24_03060)	-	534779..535471 (+)	693	WP_001011647.1	amino acid ABC transporter permease	-
EXA24_RS02970 (EXA24_03065)	-	535464..536198 (+)	735	WP_000230128.1	amino acid ABC transporter ATP-binding protein	-
EXA24_RS02975 (EXA24_03070)	-	536485..538179 (+)	1695	WP_001106852.1	phospho-sugar mutase	-

Sequence

Protein

• Length: 753 a.a.
• Molecular weight: 83789.01 Da
• Isoelectric Point: 5.2771

>NTDB_id=348281 EXA24_RS02955 WP_000882548.1 531847..534108(-) (clpE) [Streptococcus agalactiae strain Sag153]
MLCQNCKLNESTIHLYTNVNGKQKQVDLCQNCYQIIKTDPNNPLFSGLNHVSHAPGGINPFFDDFFGDLNNFRAFNGQDL
PNTPPTQSGGNRGGGNGNGRNNNRNQTATPPQAKGILEEFGINVTEIARHGDIDPVIGRDSEIIRVIEILNRRTKNNPVL
IGEPGVGKTAVVEGLAQKIVDGNVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRQRQDVILFIDEIHEIVG
AGTAGEGSMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILKGIQKKYEDYHHVKY
NNDAIEAAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKEIDQRLIEAENLKVQATREEDYERAAYFRDQIAK
YKEMQQQKVDDQDTPIITEKTIEHIIEEKTNIPVGDLKEKEQSQLINLADDLKQHVIGQDDAVIKIAKAIRRNRVGLGSP
NRPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLI
LLDEIEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGSGKTEASVGFGASREGRTNSVLGQLGNFFSPEF
MNRFDGIIEFKALDKENLLNIVDIMLSDVNARLAINGIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQEHIEDAITDYY
LENPSEKELRAIMTSNGNIIIKSSKKTEESAKG

Nucleotide

• Length: 2262 bp

>NTDB_id=348281 EXA24_RS02955 WP_000882548.1 531847..534108(-) (clpE) [Streptococcus agalactiae strain Sag153]
ATGCTCTGTCAAAACTGCAAACTAAACGAATCAACTATTCATTTGTATACAAATGTTAATGGAAAACAAAAGCAAGTTGA
TCTTTGTCAAAATTGCTACCAAATTATTAAAACTGACCCTAATAATCCACTTTTTTCAGGTTTAAATCATGTTTCACATG
CGCCTGGTGGCATCAATCCTTTCTTTGATGATTTCTTTGGAGATTTAAATAATTTCAGAGCCTTTAATGGCCAAGATTTA
CCAAACACTCCTCCTACACAATCAGGAGGAAACCGAGGTGGAGGAAACGGTAATGGACGAAATAATAATCGCAACCAAAC
TGCAACTCCTCCTCAAGCCAAAGGGATTCTAGAAGAATTTGGTATCAATGTCACTGAAATAGCCCGCCATGGTGATATTG
ACCCTGTTATTGGACGTGACTCAGAAATTATTCGTGTTATCGAAATCCTTAATCGTCGTACAAAAAATAATCCTGTACTT
ATTGGTGAACCCGGCGTAGGGAAAACTGCTGTTGTTGAAGGACTTGCTCAGAAAATTGTTGATGGTAATGTGCCTCATAA
ACTTCAAGGCAAACAAGTTATTCGTTTGGATGTTGTGAGTCTAGTACAAGGAACGGGCATTCGTGGTCAATTTGAAGAAC
GCATGCAAAAGTTGATGGAAGAAATTCGTCAACGTCAAGATGTTATTCTATTCATAGATGAAATTCACGAAATAGTTGGA
GCTGGTACAGCTGGCGAAGGTAGTATGGATGCAGGTAATATTTTAAAACCTGCCCTTGCACGTGGAGAATTACAACTAGT
AGGTGCTACTACTCTCAATGAATATCGTATTATCGAAAAGGACGCTGCCTTAGAACGCCGTATGCAACCTGTAAAAGTCG
ATGAGCCTTCTGTTGAAGAAACCATTACTATTTTGAAAGGTATCCAAAAAAAATACGAAGATTATCATCACGTAAAATAT
AATAATGATGCCATAGAAGCAGCTGCAGTACTATCTAATCGTTATATCCAAGACCGCTTTTTACCTGATAAAGCAATAGA
CTTATTAGATGAAGCTGGTTCTAAAATGAACCTAACACTAAATTTTGTTGATCCAAAAGAAATTGATCAACGTCTCATTG
AAGCAGAAAATTTAAAAGTGCAAGCGACTCGTGAAGAAGATTACGAACGTGCAGCTTACTTCCGTGACCAGATTGCAAAA
TATAAAGAAATGCAACAACAAAAGGTCGACGATCAAGATACACCTATTATTACCGAAAAAACAATTGAGCACATCATTGA
AGAAAAAACGAATATCCCTGTTGGTGATTTAAAAGAAAAAGAACAATCTCAATTAATTAATCTCGCAGATGACTTGAAAC
AACATGTGATCGGCCAGGATGACGCTGTCATTAAGATTGCAAAAGCTATTCGTCGTAATCGTGTTGGTCTTGGTAGCCCA
AACCGTCCTATTGGTTCCTTTTTATTTGTAGGACCAACCGGTGTTGGTAAAACTGAACTTTCTAAACAACTAGCAATTGA
GCTCTTTGGTTCAGCTGATAGTATGATTCGTTTTGATATGTCAGAGTACATGGAAAAGCATGCTGTTGCTAAATTAGTCG
GAGCGCCTCCAGGATACGTGGGATACGAGGAAGCTGGACAATTAACTGAAAAGGTTCGTCGAAATCCTTACTCGCTCATC
CTTCTAGATGAAATTGAAAAAGCTCATCCTGATGTCATGCATATGTTCTTGCAGGTCCTTGATGACGGTCGATTAACAGA
TGGACAAGGAAGAACTGTTAGTTTTAAAGATACCATTATCATCATGACCTCAAATGCTGGTTCTGGTAAAACTGAAGCAA
GCGTTGGCTTTGGTGCCTCACGAGAAGGTAGGACGAATTCCGTACTAGGTCAACTAGGTAACTTCTTCAGCCCTGAATTT
ATGAACCGCTTTGACGGTATTATTGAATTCAAGGCTTTAGATAAAGAGAATCTCCTCAATATCGTTGATATTATGTTATC
TGACGTTAATGCACGTCTCGCCATCAATGGTATTCATCTAGATGTCACTGATAAAGTGAAAGAAAAATTGGTTGATTTAG
GTTACGATCCAAAAATGGGAGCACGTCCATTACGTCGTACCATTCAAGAACATATTGAAGATGCTATCACAGATTACTAT
CTTGAGAATCCAAGCGAAAAAGAACTTCGTGCTATTATGACTAGCAATGGAAATATCATAATAAAATCTTCTAAAAAAAC
TGAGGAAAGTGCAAAAGGTTGA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (482-645)

• AAA lid domain (AAA_lid_9) (297-394)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (653-727)

• ATPase family associated with various cellular activities (AAA) (AAA) (159-276)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	85.411	100	0.855
clpE	Streptococcus pneumoniae Rx1	85.581	99.469	0.851
clpE	Streptococcus pneumoniae D39	85.581	99.469	0.851
clpE	Streptococcus pneumoniae R6	85.581	99.469	0.851
clpE	Streptococcus pneumoniae TIGR4	85.447	99.469	0.85
clpC	Lactococcus lactis subsp. cremoris KW2	74.734	99.867	0.746
clpC	Bacillus subtilis subsp. subtilis str. 168	51.18	90.04	0.461
clpC	Streptococcus pneumoniae Rx1	47.003	84.197	0.396
clpC	Streptococcus pneumoniae D39	47.003	84.197	0.396
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.368	83.267	0.394
clpC	Streptococcus pneumoniae TIGR4	46.845	84.197	0.394
clpC	Streptococcus mutans UA159	47.03	82.736	0.389
clpC	Streptococcus thermophilus LMD-9	46.117	83.798	0.386
clpC	Streptococcus thermophilus LMG 18311	45.8	83.798	0.384