Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   EXW57_RS18795 Genome accession   NZ_CP036145
Coordinates   3711910..3712689 (-) Length   259 a.a.
NCBI ID   WP_002014541.1    Uniprot ID   -
Organism   Bacillus mycoides strain JAS94/5     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3680386..3747399 3711910..3712689 within 0


Gene organization within MGE regions


Location: 3680386..3747399
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXW57_RS18650 (EXW57_19045) dapA 3680450..3681328 (-) 879 WP_002014579.1 4-hydroxy-tetrahydrodipicolinate synthase -
  EXW57_RS18655 (EXW57_19050) dapG 3681340..3682572 (-) 1233 WP_002088068.1 aspartate kinase -
  EXW57_RS18660 (EXW57_19055) asd 3682596..3683642 (-) 1047 WP_002014577.1 aspartate-semialdehyde dehydrogenase -
  EXW57_RS18665 (EXW57_19060) dpaB 3683792..3684391 (-) 600 WP_002111357.1 dipicolinate synthase subunit B -
  EXW57_RS18670 (EXW57_19065) dpaA 3684388..3685290 (-) 903 WP_002128797.1 dipicolinic acid synthetase subunit A -
  EXW57_RS18675 (EXW57_19070) - 3685463..3685711 (-) 249 WP_002014571.1 YlmC/YmxH family sporulation protein -
  EXW57_RS18680 (EXW57_19075) - 3685847..3687088 (-) 1242 WP_002088150.1 pitrilysin family protein -
  EXW57_RS18685 (EXW57_19080) - 3687175..3688074 (-) 900 WP_002128798.1 polysaccharide deacetylase family protein -
  EXW57_RS18690 (EXW57_19085) pnp 3688229..3690382 (-) 2154 WP_002128799.1 polyribonucleotide nucleotidyltransferase -
  EXW57_RS18695 (EXW57_19090) rpsO 3690544..3690813 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  EXW57_RS18700 (EXW57_19095) ribF 3690914..3691885 (-) 972 WP_002128800.1 bifunctional riboflavin kinase/FAD synthetase -
  EXW57_RS18705 (EXW57_19100) truB 3691929..3692852 (-) 924 WP_002014562.1 tRNA pseudouridine(55) synthase TruB -
  EXW57_RS18710 (EXW57_19105) rbfA 3692943..3693299 (-) 357 WP_000776437.1 30S ribosome-binding factor RbfA -
  EXW57_RS18715 (EXW57_19110) - 3693315..3693596 (-) 282 WP_002088157.1 DUF503 family protein -
  EXW57_RS18720 (EXW57_19115) infB 3693593..3695659 (-) 2067 WP_002014558.1 translation initiation factor IF-2 -
  EXW57_RS18725 (EXW57_19120) - 3695664..3695975 (-) 312 WP_001286519.1 YlxQ family RNA-binding protein -
  EXW57_RS18730 (EXW57_19125) - 3695976..3696248 (-) 273 WP_002088161.1 YlxR family protein -
  EXW57_RS18735 (EXW57_19130) nusA 3696260..3697366 (-) 1107 WP_002014554.1 transcription termination factor NusA -
  EXW57_RS18740 (EXW57_19135) rimP 3697384..3697854 (-) 471 WP_002088165.1 ribosome maturation factor RimP -
  EXW57_RS18745 (EXW57_19140) - 3698188..3702489 (-) 4302 WP_002033677.1 PolC-type DNA polymerase III -
  EXW57_RS18750 (EXW57_19145) - 3702614..3704314 (-) 1701 WP_002128803.1 proline--tRNA ligase -
  EXW57_RS18755 (EXW57_19150) rseP 3704424..3705680 (-) 1257 WP_002088169.1 RIP metalloprotease RseP -
  EXW57_RS18760 (EXW57_19155) dxr 3705698..3706840 (-) 1143 WP_002014547.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  EXW57_RS18765 (EXW57_19160) cdsA 3706864..3707655 (-) 792 WP_002088171.1 phosphatidate cytidylyltransferase -
  EXW57_RS18770 (EXW57_19165) uppS 3707673..3708449 (-) 777 WP_033731196.1 isoprenyl transferase -
  EXW57_RS18775 (EXW57_19170) frr 3708535..3709092 (-) 558 WP_000531506.1 ribosome recycling factor -
  EXW57_RS18780 (EXW57_19175) pyrH 3709096..3709818 (-) 723 WP_002014544.1 UMP kinase -
  EXW57_RS18785 (EXW57_19180) tsf 3709885..3710772 (-) 888 WP_002088177.1 translation elongation factor Ts -
  EXW57_RS18790 (EXW57_19185) rpsB 3710855..3711556 (-) 702 WP_002185070.1 30S ribosomal protein S2 -
  EXW57_RS18795 (EXW57_19190) codY 3711910..3712689 (-) 780 WP_002014541.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  EXW57_RS18800 (EXW57_19195) hslU 3712767..3714158 (-) 1392 WP_002014539.1 ATP-dependent protease ATPase subunit HslU -
  EXW57_RS18805 (EXW57_19200) hslV 3714181..3714723 (-) 543 WP_002014538.1 ATP-dependent protease proteolytic subunit HslV -
  EXW57_RS18810 (EXW57_19205) xerC 3714766..3715665 (-) 900 WP_078175468.1 tyrosine recombinase XerC -
  EXW57_RS18815 (EXW57_19210) trmFO 3715737..3717041 (-) 1305 WP_002066796.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  EXW57_RS18820 (EXW57_19215) topA 3717090..3719168 (-) 2079 WP_002088184.1 type I DNA topoisomerase -
  EXW57_RS18825 (EXW57_19220) dprA 3719313..3720182 (-) 870 WP_033731198.1 DNA-processing protein DprA -
  EXW57_RS18830 (EXW57_19225) sucD 3720271..3721173 (-) 903 WP_002033796.1 succinate--CoA ligase subunit alpha -
  EXW57_RS18835 (EXW57_19230) sucC 3721193..3722353 (-) 1161 WP_002014529.1 ADP-forming succinate--CoA ligase subunit beta -
  EXW57_RS18840 (EXW57_19235) - 3722547..3723320 (-) 774 WP_002014527.1 ribonuclease HII -
  EXW57_RS18845 (EXW57_19240) ylqF 3723376..3724266 (-) 891 WP_002128821.1 ribosome biogenesis GTPase YlqF -
  EXW57_RS18850 (EXW57_19245) lepB 3724287..3724838 (-) 552 WP_002066791.1 signal peptidase I -
  EXW57_RS18855 (EXW57_19250) rplS 3724939..3725283 (-) 345 WP_002014524.1 50S ribosomal protein L19 -
  EXW57_RS18860 (EXW57_19255) trmD 3725430..3726164 (-) 735 WP_002014522.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  EXW57_RS18865 (EXW57_19260) rimM 3726164..3726679 (-) 516 WP_002014521.1 ribosome maturation factor RimM -
  EXW57_RS18870 (EXW57_19265) - 3726801..3727028 (-) 228 WP_002088196.1 KH domain-containing protein -
  EXW57_RS18875 (EXW57_19270) rpsP 3727043..3727315 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  EXW57_RS18880 (EXW57_19275) ffh 3727416..3728765 (-) 1350 WP_002014519.1 signal recognition particle protein -
  EXW57_RS18885 (EXW57_19280) - 3728778..3729110 (-) 333 WP_215563593.1 putative DNA-binding protein -
  EXW57_RS18890 (EXW57_19285) ftsY 3729243..3730232 (-) 990 WP_002088200.1 signal recognition particle-docking protein FtsY -
  EXW57_RS18895 (EXW57_19290) smc 3730247..3733816 (-) 3570 WP_002014517.1 chromosome segregation protein SMC -
  EXW57_RS18900 (EXW57_19295) rncS 3733965..3734702 (-) 738 WP_002033792.1 ribonuclease III -
  EXW57_RS18905 (EXW57_19300) acpP 3734761..3734994 (-) 234 WP_002014515.1 acyl carrier protein -
  EXW57_RS18910 (EXW57_19305) fabG 3735064..3735804 (-) 741 WP_002014514.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  EXW57_RS18915 (EXW57_19310) fabD 3735804..3736748 (-) 945 WP_002128825.1 ACP S-malonyltransferase -
  EXW57_RS18920 (EXW57_19315) plsX 3736763..3737755 (-) 993 WP_002128828.1 phosphate acyltransferase PlsX -
  EXW57_RS18925 (EXW57_19320) fapR 3737752..3738345 (-) 594 WP_000747354.1 transcription factor FapR -
  EXW57_RS18930 (EXW57_19325) recG 3738434..3740482 (-) 2049 WP_002014510.1 ATP-dependent DNA helicase RecG -
  EXW57_RS18935 (EXW57_19330) - 3740907..3742583 (-) 1677 WP_002128829.1 DAK2 domain-containing protein -
  EXW57_RS18940 (EXW57_19335) - 3742606..3742968 (-) 363 WP_002014507.1 Asp23/Gls24 family envelope stress response protein -
  EXW57_RS18945 (EXW57_19340) rpmB 3743347..3743535 (+) 189 WP_000124776.1 50S ribosomal protein L28 -
  EXW57_RS18950 (EXW57_19345) spoVM 3743609..3743689 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  EXW57_RS18955 (EXW57_19350) - 3743756..3744436 (-) 681 WP_002014506.1 thiamine diphosphokinase -
  EXW57_RS18960 (EXW57_19355) rpe 3744537..3745181 (-) 645 WP_002014505.1 ribulose-phosphate 3-epimerase -
  EXW57_RS18965 (EXW57_19360) rsgA 3745184..3746065 (-) 882 WP_002014503.1 ribosome small subunit-dependent GTPase A -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28774.99 Da        Isoelectric Point: 4.7251

>NTDB_id=347131 EXW57_RS18795 WP_002014541.1 3711910..3712689(-) (codY) [Bacillus mycoides strain JAS94/5]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKHMLAERQFPEEYTQSLF
NVTETSSNLGVDSDYTAFPVENRELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLQELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=347131 EXW57_RS18795 WP_002014541.1 3711910..3712689(-) (codY) [Bacillus mycoides strain JAS94/5]
ATGGAATTATTAGCAAAAACGAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAGAT
GTCTGACACAATGTGTGAAGTAATTGAAGCGAACGTGTTCGTTGTAAGTCGTCGCGGTAAATTATTAGGATATGCGATTC
ACCAACAAATCGAAAACGAACGTATGAAGCACATGCTTGCAGAGCGTCAATTCCCAGAAGAGTATACGCAAAGTTTATTC
AATGTTACAGAAACATCTTCAAATTTAGGTGTGGATAGTGACTACACAGCATTCCCGGTAGAAAATAGAGAATTATTCGG
TCAAGGTTTAACTACAATCGTACCAATCGTTGGTGGCGGTGAGCGTCTAGGTACACTAGTATTAGCTCGTCTTGGTCAAG
AGTTCTTAGACGATGATTTAATTCTTGCTGAATACAGCTCAACTGTTGTAGGTATGGAAATCTTACGTGAAAAAGCAGAA
GAAATCGAAGAGGAAGCACGTAGTAAAGCTGTTGTTCAAATGGCGATTAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
CGAGCATATCTTCGAAGAATTAAATGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGATCGCGTCGGAATTACTC
GTTCGGTAATCGTAAATGCACTACGTAAATTAGAAAGTGCTGGTGTTATTGAGTCTCGCTCTTTAGGTATGAAAGGAACA
TACATTAAAGTGCTAAACGACAAGTTTCTACAGGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY helix-turn-helix domain (HTH_CodY)

(198-255)

CodY GAF-like domain (CodY)

(2-178)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.081

100

0.811
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.275

98.456

0.456

Multiple sequence alignment