Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   EXW43_RS25685 Genome accession   NZ_CP036117
Coordinates   4889030..4889611 (+) Length   193 a.a.
NCBI ID   WP_001049156.1    Uniprot ID   J8DR96
Organism   Bacillus mycoides strain JAS481     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 4884030..4894611
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXW43_RS25650 (EXW43_26200) - 4885013..4885219 (+) 207 WP_000216167.1 DUF1657 domain-containing protein -
  EXW43_RS25655 (EXW43_26205) - 4885326..4885814 (+) 489 WP_002167400.1 YhcN/YlaJ family sporulation lipoprotein -
  EXW43_RS25660 (EXW43_26210) spoVAC 4885843..4886319 (+) 477 WP_002129887.1 stage V sporulation protein AC -
  EXW43_RS25665 (EXW43_26215) spoVAD 4886320..4887336 (+) 1017 WP_078213831.1 stage V sporulation protein AD -
  EXW43_RS25670 (EXW43_26220) spoVAE 4887333..4887683 (+) 351 WP_000575919.1 stage V sporulation protein AE -
  EXW43_RS25675 (EXW43_26225) - 4887693..4887899 (+) 207 WP_002167398.1 DUF1657 domain-containing protein -
  EXW43_RS25680 (EXW43_26230) - 4887920..4888789 (+) 870 WP_002016080.1 DUF421 domain-containing protein -
  EXW43_RS25685 (EXW43_26235) clpP 4889030..4889611 (+) 582 WP_001049156.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  EXW43_RS25690 (EXW43_26240) - 4889862..4890110 (-) 249 WP_002016081.1 HPr family phosphocarrier protein -
  EXW43_RS25695 (EXW43_26245) whiA 4890134..4891084 (-) 951 WP_002016082.1 DNA-binding protein WhiA -
  EXW43_RS25700 (EXW43_26250) yvcK 4891173..4892126 (-) 954 WP_002016083.1 YvcK family protein -
  EXW43_RS25705 (EXW43_26255) rapZ 4892130..4893011 (-) 882 WP_002016084.1 RNase adapter RapZ -
  EXW43_RS25710 (EXW43_26260) - 4893032..4893490 (-) 459 WP_001190080.1 8-oxo-dGTP diphosphatase -
  EXW43_RS25715 (EXW43_26265) - 4893706..4894512 (-) 807 WP_002016085.1 DUF368 domain-containing protein -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21431.68 Da        Isoelectric Point: 5.0423

>NTDB_id=346946 EXW43_RS25685 WP_001049156.1 4889030..4889611(+) (clpP) [Bacillus mycoides strain JAS481]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHIYINSPGGSITAGMAIYDT
MQFIKPQVSTICIGMAASMGAFLLAAGEKGKRFALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLREKLNQILADRTGQ
PLEVLQRDTDRDNFMTAERALEYGLIDKIFTNR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=346946 EXW43_RS25685 WP_001049156.1 4889030..4889611(+) (clpP) [Bacillus mycoides strain JAS481]
ATGAATTTAATTCCTACAGTAATTGAACAAACAAATCGTGGAGAACGCGCTTACGATATTTACTCTCGACTATTAAAGGA
TCGCATCATTATGCTTGGTAGCGCAATTGATGACAATGTAGCAAACTCAATCGTTTCCCAGCTTTTATTCTTGGAATCTC
AAGATCCAGAAAAAGATATTCACATTTACATCAACAGCCCTGGTGGTTCTATCACAGCTGGTATGGCAATTTACGATACA
ATGCAGTTTATTAAACCACAAGTATCAACAATCTGTATCGGTATGGCTGCATCTATGGGTGCATTCTTACTTGCAGCAGG
TGAAAAAGGAAAACGTTTCGCTCTTCCTAACAGTGAAGTAATGATTCACCAACCACTTGGCGGTGCACAAGGTCAAGCGA
CTGAAATCGAAATCGCTGCAAAACGTATCCTATTCTTACGTGAAAAATTAAACCAAATTCTTGCTGACCGCACAGGTCAA
CCACTTGAAGTTCTACAACGCGACACAGATCGCGACAACTTCATGACAGCAGAAAGAGCTCTAGAATACGGCTTAATCGA
TAAGATCTTTACAAATCGTTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J8DR96

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

89.583

99.482

0.891
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.553

97.409

0.658
  clpP Streptococcus thermophilus LMG 18311

60.938

99.482

0.606
  clpP Streptococcus thermophilus LMD-9

60.938

99.482

0.606
  clpP Lactococcus lactis subsp. cremoris KW2

59.375

99.482

0.591
  clpP Streptococcus pneumoniae D39

57.812

99.482

0.575
  clpP Streptococcus pneumoniae Rx1

57.812

99.482

0.575
  clpP Streptococcus pneumoniae R6

57.812

99.482

0.575
  clpP Streptococcus pneumoniae TIGR4

57.812

99.482

0.575
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

57.292

99.482

0.57
  clpP Streptococcus mutans UA159

55.959

100

0.56
  clpP Streptococcus pyogenes JRS4

56.25

99.482

0.56
  clpP Streptococcus pyogenes MGAS315

56.25

99.482

0.56

Multiple sequence alignment