Detailed information NTG0034679

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SSUBM407_RS08120
• Genome accession: NC_012926
• Coordinates: 1645693..1646742 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis BM407
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1640693..1651742

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUBM407_RS08100 (SSUBM407_1560)	nadE	1641099..1641923 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
SSUBM407_RS08105 (SSUBM407_1561)	-	1643219..1643746 (-)	528	WP_012027591.1	VanZ family protein	-
SSUBM407_RS08110 (SSUBM407_1562)	rlmN	1643743..1644855 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SSUBM407_RS08115 (SSUBM407_1563)	-	1644864..1645505 (-)	642	WP_012027595.1	YutD family protein	-
SSUBM407_RS08120 (SSUBM407_1564)	sepM	1645693..1646742 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
SSUBM407_RS08125 (SSUBM407_1565)	coaD	1646729..1647217 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
SSUBM407_RS08130 (SSUBM407_1566)	rsmD	1647207..1647746 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SSUBM407_RS08135 (SSUBM407_1567)	-	1648054..1648776 (-)	723	WP_012027598.1	lipoprotein	-
SSUBM407_RS08140 (SSUBM407_1568)	-	1648833..1649219 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
SSUBM407_RS08145 (SSUBM407_1569)	-	1649219..1649437 (-)	219	WP_004194736.1	YqgQ family protein	-
SSUBM407_RS08150 (SSUBM407_1570)	-	1649745..1650347 (-)	603	WP_012027601.1	response regulator transcription factor	-
SSUBM407_RS08155 (SSUBM407_1571)	-	1650344..1651438 (-)	1095	WP_050069059.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=34679 SSUBM407_RS08120 WP_012775295.1 1645693..1646742(-) (sepM) [Streptococcus suis BM407]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=34679 SSUBM407_RS08120 WP_012775295.1 1645693..1646742(-) (sepM) [Streptococcus suis BM407]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605