Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   EXW54_RS25280 Genome accession   NZ_CP036094
Coordinates   4957797..4958378 (+) Length   193 a.a.
NCBI ID   WP_001049156.1    Uniprot ID   J8DR96
Organism   Bacillus toyonensis strain JAS22/1     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 4952797..4963378
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXW54_RS30115 - 4953288..4953344 (-) 57 Protein_4947 hypothetical protein -
  EXW54_RS30120 - 4953396..4953573 (-) 178 Protein_4948 ABC transporter ATP-binding protein -
  EXW54_RS25245 (EXW54_25840) - 4953777..4953983 (+) 207 WP_000216160.1 DUF1657 domain-containing protein -
  EXW54_RS25250 (EXW54_25845) - 4954090..4954578 (+) 489 WP_001228525.1 YhcN/YlaJ family sporulation lipoprotein -
  EXW54_RS25255 (EXW54_25850) spoVAC 4954607..4955083 (+) 477 WP_000095411.1 stage V sporulation protein AC -
  EXW54_RS25260 (EXW54_25855) spoVAD 4955084..4956100 (+) 1017 WP_000938947.1 stage V sporulation protein AD -
  EXW54_RS25265 (EXW54_25860) spoVAE 4956097..4956447 (+) 351 WP_000575919.1 stage V sporulation protein AE -
  EXW54_RS25270 (EXW54_25865) - 4956459..4956665 (+) 207 WP_000215895.1 DUF1657 domain-containing protein -
  EXW54_RS25275 (EXW54_25870) - 4956686..4957555 (+) 870 WP_000018941.1 DUF421 domain-containing protein -
  EXW54_RS25280 (EXW54_25875) clpP 4957797..4958378 (+) 582 WP_001049156.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  EXW54_RS25285 (EXW54_25880) - 4958789..4959037 (-) 249 WP_000250298.1 HPr family phosphocarrier protein -
  EXW54_RS25290 (EXW54_25885) whiA 4959061..4960011 (-) 951 WP_000006570.1 DNA-binding protein WhiA -
  EXW54_RS25295 (EXW54_25890) - 4960101..4961054 (-) 954 WP_070173938.1 YvcK family protein -
  EXW54_RS25300 (EXW54_25895) rapZ 4961058..4961939 (-) 882 WP_000138467.1 RNase adapter RapZ -
  EXW54_RS25305 (EXW54_25900) - 4961960..4962418 (-) 459 WP_001190080.1 8-oxo-dGTP diphosphatase -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21431.68 Da        Isoelectric Point: 5.0423

>NTDB_id=346700 EXW54_RS25280 WP_001049156.1 4957797..4958378(+) (clpP) [Bacillus toyonensis strain JAS22/1]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLESQDPEKDIHIYINSPGGSITAGMAIYDT
MQFIKPQVSTICIGMAASMGAFLLAAGEKGKRFALPNSEVMIHQPLGGAQGQATEIEIAAKRILFLREKLNQILADRTGQ
PLEVLQRDTDRDNFMTAERALEYGLIDKIFTNR

Nucleotide


Download         Length: 582 bp        

>NTDB_id=346700 EXW54_RS25280 WP_001049156.1 4957797..4958378(+) (clpP) [Bacillus toyonensis strain JAS22/1]
ATGAATTTAATTCCTACAGTAATTGAACAAACAAATCGTGGAGAACGCGCTTACGATATTTACTCTCGACTATTAAAAGA
CCGCATCATTATGCTTGGTAGTGCAATTGATGACAACGTAGCTAACTCAATTGTTTCCCAGCTTTTATTCTTGGAATCTC
AAGATCCAGAAAAAGATATTCACATCTACATCAATAGCCCTGGTGGTTCTATCACAGCAGGTATGGCAATTTACGATACA
ATGCAGTTTATTAAACCACAAGTATCAACAATCTGTATCGGTATGGCTGCATCTATGGGTGCATTCTTACTTGCAGCAGG
TGAAAAAGGAAAACGTTTCGCTCTTCCTAATAGTGAAGTAATGATTCACCAACCACTTGGCGGAGCACAAGGTCAAGCGA
CTGAAATCGAAATCGCTGCAAAACGTATCCTATTCTTACGTGAAAAATTAAACCAAATTCTTGCTGACCGCACAGGTCAA
CCACTTGAAGTACTACAACGCGACACAGACCGCGACAACTTCATGACAGCAGAAAGAGCTTTAGAATACGGCTTAATTGA
TAAGATCTTTACAAATCGTTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB J8DR96

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

89.583

99.482

0.891
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

67.553

97.409

0.658
  clpP Streptococcus thermophilus LMG 18311

60.938

99.482

0.606
  clpP Streptococcus thermophilus LMD-9

60.938

99.482

0.606
  clpP Lactococcus lactis subsp. cremoris KW2

59.375

99.482

0.591
  clpP Streptococcus pneumoniae D39

57.812

99.482

0.575
  clpP Streptococcus pneumoniae Rx1

57.812

99.482

0.575
  clpP Streptococcus pneumoniae R6

57.812

99.482

0.575
  clpP Streptococcus pneumoniae TIGR4

57.812

99.482

0.575
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

57.292

99.482

0.57
  clpP Streptococcus mutans UA159

55.959

100

0.56
  clpP Streptococcus pyogenes JRS4

56.25

99.482

0.56
  clpP Streptococcus pyogenes MGAS315

56.25

99.482

0.56

Multiple sequence alignment