Detailed information NTG0346688

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: EXW54_RS20585
• Genome accession: NZ_CP036094
• Coordinates: 4105609..4106403 (-)
• Length: 264 a.a.
• NCBI ID: WP_000411416.1
• Uniprot ID: A0A1G4L491
• Organism: Bacillus toyonensis strain JAS22/1
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 4100609..4111403

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EXW54_RS20565 (EXW54_21065)	-	4100610..4101338 (-)	729	WP_000172596.1	glycerophosphodiester phosphodiesterase	-
EXW54_RS20570 (EXW54_21070)	-	4101389..4101535 (+)	147	WP_001247671.1	YycC family protein	-
EXW54_RS20575 (EXW54_21075)	-	4101764..4103089 (-)	1326	WP_000395075.1	glycosyltransferase	-
EXW54_RS20580 (EXW54_21080)	-	4103289..4104707 (-)	1419	WP_001193753.1	membrane protein	-
EXW54_RS20585 (EXW54_21085)	spo0A	4105609..4106403 (-)	795	WP_000411416.1	sporulation transcription factor Spo0A	Regulator
EXW54_RS20590 (EXW54_21095)	spoIVB	4106692..4107990 (-)	1299	WP_002048975.1	SpoIVB peptidase	-
EXW54_RS20595 (EXW54_21100)	recN	4108109..4109848 (-)	1740	WP_000947741.1	DNA repair protein RecN	Machinery gene
EXW54_RS20600 (EXW54_21105)	argR	4110110..4110559 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29427.13 Da
• Isoelectric Point: 7.1176

>NTDB_id=346688 EXW54_RS20585 WP_000411416.1 4105609..4106403(-) (spo0A) [Bacillus toyonensis strain JAS22/1]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLTDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTIDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=346688 EXW54_RS20585 WP_000411416.1 4105609..4106403(-) (spo0A) [Bacillus toyonensis strain JAS22/1]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAACTTATTAACAGATAAGCAGCCTGATGTACTCG
TTTTAGACATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTAACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACCTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAGAATTTAACTAGTCATATTCGTCAAGTGAGTGGCAAGGCAAATGCTACTATTAAACGTCCAT
TACCATCTTTCCGATCAGCAACAACAATAGATGGAAAACCGAAAAACTTAGATGCAAGTATTACGAGTATTATTCATGAA
ATTGGTGTACCTGCTCATATTAAAGGATACATGTACTTACGAGAAGCGATTTCTATGGTGTACAATGATATCGAATTACT
AGGGTCTATTACGAAAGTATTATATCCAGATATTGCAAAGAAATATAATACAACAGCGAGCCGTGTCGAGCGTGCAATCC
GTCACGCGATTGAAGTAGCGTGGAGCCGTGGAAATATTGATTCTATTTCGTCCTTATTTGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAATTCTGAGTTTATCGCAATGGTTGCGGATAAGTTGAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (6-119)

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

3D structure

• AlphaFold DB: A0A1G4L491

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.524	100	0.814