Detailed information NTG0034659

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: SAVC_RS04345
• Genome accession: NC_016912
• Coordinates: 881433..884042 (+)
• Length: 869 a.a.
• NCBI ID: WP_000353970.1
• Uniprot ID: Q2FZS8
• Organism: Staphylococcus aureus subsp. aureus VC40
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 876433..889042

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAVC_RS04330 (SAVC_04030)	-	877623..878447 (-)	825	WP_001182436.1	Cof-type HAD-IIB family hydrolase	-
SAVC_RS04335 (SAVC_04035)	-	878561..878869 (+)	309	WP_000390575.1	metal-sulfur cluster assembly factor	-
SAVC_RS04340 (SAVC_04040)	-	879416..881230 (+)	1815	WP_001044214.1	acyltransferase family protein	-
SAVC_RS04345 (SAVC_04045)	clpC	881433..884042 (+)	2610	WP_000353970.1	ATP-dependent chaperone ClpB	Regulator
SAVC_RS04350 (SAVC_04050)	-	884101..884970 (-)	870	WP_001047066.1	LysR family transcriptional regulator	-
SAVC_RS04355 (SAVC_04055)	-	885080..886225 (+)	1146	WP_000619365.1	LeuA family protein	-
SAVC_RS04360 (SAVC_04060)	-	886209..886850 (+)	642	WP_000404422.1	L-threonylcarbamoyladenylate synthase	-
SAVC_RS04365 (SAVC_04065)	-	886843..887961 (+)	1119	WP_001037436.1	MFS transporter	-
SAVC_RS04370 (SAVC_04070)	-	887945..888460 (+)	516	WP_000695342.1	YbhB/YbcL family Raf kinase inhibitor-like protein	-

Sequence

Protein

• Length: 869 a.a.
• Molecular weight: 98331.50 Da
• Isoelectric Point: 4.6833

>NTDB_id=34659 SAVC_RS04345 WP_000353970.1 881433..884042(+) (clpC) [Staphylococcus aureus subsp. aureus VC40]
MDINKMTYAVQSALQQAVELSQQHKLQNIEIEAILSAALNESESLYKSILERVNIEVDQLNKAYEDKLNTYASVEGDNIQ
YGQYISQQANQLITKAESYMKEYEDEYISMEHILRSAMDIDQTTKHYINNKVEVIKEIIKKVRGGNHVTSQNPEVNYEAL
AKYGRDLVEEVRQGKMDPVIGRDEEIRNTIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPESLLDKTVFELD
LSALVAGAKYRGEFEERLKAVLKEVKESDGRIILFIDEIHMLVGAGKTDGAMDAGNMLKPMLARGELHCIGATTLNEYRE
YIEKDSALERRFQKVAVSEPDVEDTISILRGLKERYEVYHGVRIQDRALVAAAELSDRYITDRFLPDKAIDLVDQACATI
RTEMGSNPTELDQVNRRVMQLEIEESALKNESDNASKQRLQELQEELANEKEKQAALQSRVESEKEKIANLQEKRAQLDE
SRQALEDAQTNNNLEKAAELQYGTIPQLEKELRELEDNFQDEQGEDTDRMIREVVTDEEIGDIVSQWTGIPVSKLVETER
EKLLHLSDILHKRVVGQDKAVDLVSDAVVRARAGIKDPNRPIGSFLFLGPTGVGKTELAKSLAASLFDSEKHMIRIDMSE
YMEKHAVSRLIGAPPGYIGHDEGGQLTEAVRRNPYSVILLDEVEKAHTDVFNVLLQILDEGRLTDSKGRSVDFKNTIIIM
TSNIGSQVLLENVKETGEITESTEKAVMTSLNAYFKPEILNRMDDIVLFKPLSIDDMSMIVDKILTQLNIRLLEQRISIE
VSDDAKAWLGQEAYEPQYGARPLKRFVQRQIETPLARMMIKEGFPEGTTIKVNLNSDNNLTFNVEKIHE

Nucleotide

• Length: 2610 bp

>NTDB_id=34659 SAVC_RS04345 WP_000353970.1 881433..884042(+) (clpC) [Staphylococcus aureus subsp. aureus VC40]
ATGGATATAAATAAAATGACATATGCTGTTCAAAGTGCTTTACAACAAGCAGTTGAACTGAGTCAGCAACATAAATTACA
AAATATAGAAATTGAGGCAATTTTAAGCGCTGCCTTAAATGAAAGTGAAAGCTTATATAAAAGTATTTTAGAACGAGTAA
ATATTGAGGTAGATCAATTAAACAAAGCTTATGAAGACAAACTAAACACGTATGCATCTGTAGAAGGTGACAATATACAA
TATGGTCAATATATTAGCCAACAAGCAAACCAATTGATAACTAAGGCTGAATCATACATGAAAGAATATGAAGATGAATA
TATTTCAATGGAGCATATTTTACGTTCGGCAATGGACATTGATCAAACAACAAAACATTATATAAATAATAAAGTAGAAG
TTATCAAAGAAATTATTAAAAAAGTAAGAGGGGGAAATCACGTGACATCACAAAATCCAGAAGTTAATTACGAAGCATTA
GCTAAATATGGCCGCGACTTAGTAGAAGAAGTTAGACAAGGTAAAATGGATCCTGTTATAGGAAGAGATGAAGAAATTCG
AAATACGATTCGTATTTTAAGTCGTAAAACTAAAAACAACCCTGTGCTCATTGGTGAACCAGGTGTTGGTAAAACTGCAA
TTGTTGAAGGATTAGCGCAACGTATAGTTAAGAAAGATGTGCCAGAATCATTATTAGATAAAACTGTTTTTGAGTTAGAT
TTAAGCGCATTAGTAGCGGGCGCTAAATATCGTGGTGAATTTGAAGAGAGATTAAAAGCAGTCCTAAAAGAAGTTAAAGA
GTCTGATGGTAGAATTATATTATTTATTGATGAAATCCATATGCTTGTAGGTGCTGGTAAAACAGATGGTGCCATGGATG
CAGGCAACATGCTAAAACCAATGTTAGCACGAGGAGAGTTACATTGTATTGGTGCAACAACTTTAAATGAATATCGAGAA
TATATTGAAAAAGATTCGGCATTAGAGCGTCGTTTCCAAAAAGTAGCAGTTAGTGAGCCTGATGTTGAAGATACAATTTC
AATTTTACGTGGTTTAAAAGAACGATATGAAGTGTATCATGGTGTGCGTATTCAAGATAGAGCCTTAGTTGCTGCCGCTG
AATTGTCTGATCGTTACATCACTGATCGTTTTTTACCAGATAAAGCGATTGATTTAGTTGACCAAGCATGTGCAACAATT
CGTACGGAAATGGGATCAAATCCAACTGAATTGGATCAAGTTAATAGACGTGTCATGCAATTAGAAATTGAAGAAAGCGC
ACTTAAAAATGAATCTGACAATGCGAGCAAACAGAGATTACAAGAACTACAAGAAGAGCTTGCCAATGAAAAAGAGAAAC
AAGCAGCACTTCAATCTCGTGTAGAATCAGAAAAAGAAAAAATAGCAAATTTACAAGAAAAACGTGCGCAACTAGATGAA
AGTAGACAAGCGTTGGAAGATGCACAAACAAATAACAATTTAGAAAAAGCTGCTGAACTACAATATGGAACAATTCCTCA
ATTGGAAAAAGAACTTAGAGAATTAGAGGATAATTTCCAAGATGAGCAAGGTGAAGATACAGATCGAATGATTCGTGAAG
TTGTAACAGACGAAGAAATTGGCGATATTGTCAGCCAATGGACAGGCATACCAGTTTCAAAATTAGTTGAAACAGAACGT
GAAAAATTACTTCACTTAAGTGACATCTTGCATAAACGTGTTGTAGGTCAAGATAAAGCGGTTGACCTGGTTTCAGATGC
AGTAGTTAGAGCAAGAGCAGGTATTAAAGATCCAAACAGACCTATTGGTAGTTTCTTATTCCTAGGTCCAACTGGAGTAG
GTAAAACTGAATTAGCTAAATCATTAGCTGCATCATTATTTGATTCTGAAAAACATATGATTCGTATTGATATGAGTGAA
TATATGGAAAAACATGCAGTATCAAGATTGATAGGGGCACCTCCAGGATATATTGGACATGATGAAGGGGGTCAATTAAC
TGAAGCGGTTCGTCGTAATCCATACTCAGTTATTTTATTAGATGAGGTTGAAAAAGCGCATACTGACGTCTTTAATGTAT
TATTGCAAATTTTAGATGAAGGCCGTTTAACTGATTCTAAAGGACGTAGCGTTGATTTTAAAAATACTATTATTATTATG
ACAAGTAATATTGGATCTCAAGTTTTATTAGAAAACGTAAAAGAGACTGGTGAAATTACAGAATCAACAGAAAAAGCTGT
TATGACAAGTTTAAATGCATATTTCAAACCAGAAATTTTGAATCGTATGGATGATATCGTATTATTTAAACCATTATCTA
TTGATGACATGAGTATGATTGTAGATAAAATCTTAACGCAATTAAATATAAGATTATTAGAACAACGAATCTCAATTGAA
GTTTCTGATGATGCTAAAGCTTGGCTAGGTCAAGAAGCTTATGAACCTCAATACGGTGCAAGACCATTAAAACGTTTTGT
ACAACGCCAAATTGAAACACCATTAGCACGTATGATGATTAAAGAGGGATTCCCAGAAGGTACAACGATTAAAGTTAATT
TAAATTCAGACAATAACTTAACGTTTAATGTTGAAAAAATTCATGAATAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-443)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-66)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (96-121)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (772-852)

• AAA domain (Cdc48 subfamily) (AAA_2) (600-766)

• ATPase family associated with various cellular activities (AAA) (AAA) (202-334)

3D structure

• AlphaFold DB: Q2FZS8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	42.512	99.885	0.425
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	39.749	100	0.402