Detailed information    

insolico Bioinformatically predicted

Overview

Name   codY   Type   Regulator
Locus tag   EXW45_RS20020 Genome accession   NZ_CP036073
Coordinates   3942385..3943164 (-) Length   259 a.a.
NCBI ID   WP_000421290.1    Uniprot ID   A0A9W5VKA1
Organism   Bacillus wiedmannii strain JAS08/1     
Function   repression of comK (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 3906118..3977257 3942385..3943164 within 0


Gene organization within MGE regions


Location: 3906118..3977257
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXW45_RS19860 (EXW45_20210) - 3907351..3907554 (-) 204 WP_000605020.1 YlzJ-like family protein -
  EXW45_RS19865 (EXW45_20215) tepA 3907551..3908300 (-) 750 WP_000139828.1 translocation-enhancing protein TepA -
  EXW45_RS19870 (EXW45_20220) - 3908405..3910075 (-) 1671 WP_000823080.1 ribonuclease J -
  EXW45_RS19875 (EXW45_20225) dapA 3910835..3911713 (-) 879 WP_000564777.1 4-hydroxy-tetrahydrodipicolinate synthase -
  EXW45_RS19880 (EXW45_20230) dapG 3911725..3912957 (-) 1233 WP_097914682.1 aspartate kinase -
  EXW45_RS19885 (EXW45_20235) asd 3912981..3914027 (-) 1047 WP_046957394.1 aspartate-semialdehyde dehydrogenase -
  EXW45_RS19890 (EXW45_20240) dpaB 3914178..3914777 (-) 600 WP_001049480.1 dipicolinate synthase subunit B -
  EXW45_RS19895 (EXW45_20245) dpaA 3914774..3915676 (-) 903 WP_000954740.1 dipicolinic acid synthetase subunit A -
  EXW45_RS19900 (EXW45_20250) - 3915951..3916202 (-) 252 WP_149293648.1 YlmC/YmxH family sporulation protein -
  EXW45_RS19905 (EXW45_20255) - 3916333..3917574 (-) 1242 WP_000593006.1 pitrilysin family protein -
  EXW45_RS19910 (EXW45_20260) - 3917661..3918560 (-) 900 WP_000647534.1 polysaccharide deacetylase family protein -
  EXW45_RS19915 (EXW45_20265) pnp 3918713..3920851 (-) 2139 WP_046957398.1 polyribonucleotide nucleotidyltransferase -
  EXW45_RS19920 (EXW45_20270) rpsO 3921012..3921281 (-) 270 WP_001229392.1 30S ribosomal protein S15 -
  EXW45_RS19925 (EXW45_20275) ribF 3921382..3922353 (-) 972 WP_149293647.1 bifunctional riboflavin kinase/FAD synthetase -
  EXW45_RS19930 (EXW45_20280) truB 3922397..3923320 (-) 924 WP_046957399.1 tRNA pseudouridine(55) synthase TruB -
  EXW45_RS19935 (EXW45_20285) rbfA 3923407..3923763 (-) 357 WP_000776445.1 30S ribosome-binding factor RbfA -
  EXW45_RS19940 (EXW45_20290) - 3923779..3924060 (-) 282 WP_000582364.1 DUF503 family protein -
  EXW45_RS19945 (EXW45_20295) infB 3924057..3926117 (-) 2061 WP_000036353.1 translation initiation factor IF-2 -
  EXW45_RS19950 (EXW45_20300) - 3926122..3926433 (-) 312 WP_001286521.1 YlxQ family RNA-binding protein -
  EXW45_RS19955 (EXW45_20305) - 3926434..3926706 (-) 273 WP_000071127.1 YlxR family protein -
  EXW45_RS19960 (EXW45_20310) nusA 3926718..3927824 (-) 1107 WP_000102596.1 transcription termination factor NusA -
  EXW45_RS19965 (EXW45_20315) rimP 3927842..3928312 (-) 471 WP_000359098.1 ribosome maturation factor RimP -
  EXW45_RS19970 (EXW45_20320) - 3928646..3932947 (-) 4302 WP_097917880.1 PolC-type DNA polymerase III -
  EXW45_RS19975 (EXW45_20325) - 3933072..3934772 (-) 1701 WP_046956487.1 proline--tRNA ligase -
  EXW45_RS19980 (EXW45_20330) rseP 3934882..3936138 (-) 1257 WP_046957401.1 RIP metalloprotease RseP -
  EXW45_RS19985 (EXW45_20335) dxr 3936155..3937297 (-) 1143 WP_000790363.1 1-deoxy-D-xylulose-5-phosphate reductoisomerase -
  EXW45_RS19990 (EXW45_20340) cdsA 3937321..3938112 (-) 792 WP_000813596.1 phosphatidate cytidylyltransferase -
  EXW45_RS19995 (EXW45_20345) uppS 3938130..3938906 (-) 777 WP_000971311.1 isoprenyl transferase -
  EXW45_RS20000 (EXW45_20350) frr 3938992..3939549 (-) 558 WP_000531506.1 ribosome recycling factor -
  EXW45_RS20005 (EXW45_20355) pyrH 3939552..3940274 (-) 723 WP_000042667.1 UMP kinase -
  EXW45_RS20010 (EXW45_20360) tsf 3940341..3941228 (-) 888 WP_001018585.1 translation elongation factor Ts -
  EXW45_RS20015 (EXW45_20365) rpsB 3941332..3942033 (-) 702 WP_000111484.1 30S ribosomal protein S2 -
  EXW45_RS20020 (EXW45_20370) codY 3942385..3943164 (-) 780 WP_000421290.1 GTP-sensing pleiotropic transcriptional regulator CodY Regulator
  EXW45_RS20025 (EXW45_20375) hslU 3943242..3944633 (-) 1392 WP_000550070.1 ATP-dependent protease ATPase subunit HslU -
  EXW45_RS20030 (EXW45_20380) hslV 3944656..3945198 (-) 543 WP_000526271.1 ATP-dependent protease proteolytic subunit HslV -
  EXW45_RS20035 (EXW45_20385) xerC 3945241..3946140 (-) 900 WP_001101235.1 tyrosine recombinase XerC -
  EXW45_RS20040 (EXW45_20390) trmFO 3946206..3947510 (-) 1305 WP_000211996.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  EXW45_RS20045 (EXW45_20395) topA 3947559..3949637 (-) 2079 WP_001286953.1 type I DNA topoisomerase -
  EXW45_RS20050 (EXW45_20400) dprA 3949782..3950651 (-) 870 WP_000818024.1 DNA-processing protein DprA -
  EXW45_RS20055 (EXW45_20405) sucD 3950739..3951641 (-) 903 WP_149293646.1 succinate--CoA ligase subunit alpha -
  EXW45_RS20060 (EXW45_20410) sucC 3951661..3952821 (-) 1161 WP_001020778.1 ADP-forming succinate--CoA ligase subunit beta -
  EXW45_RS20065 (EXW45_20415) - 3953016..3953789 (-) 774 WP_046956485.1 ribonuclease HII -
  EXW45_RS20070 (EXW45_20420) ylqF 3953841..3954731 (-) 891 WP_000236709.1 ribosome biogenesis GTPase YlqF -
  EXW45_RS20075 (EXW45_20425) lepB 3954752..3955303 (-) 552 WP_000711855.1 signal peptidase I -
  EXW45_RS20080 (EXW45_20430) rplS 3955405..3955749 (-) 345 WP_001186518.1 50S ribosomal protein L19 -
  EXW45_RS20085 (EXW45_20435) trmD 3955896..3956630 (-) 735 WP_000686894.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  EXW45_RS20090 (EXW45_20440) rimM 3956630..3957145 (-) 516 WP_000170282.1 ribosome maturation factor RimM -
  EXW45_RS20095 (EXW45_20445) - 3957267..3957494 (-) 228 WP_000737397.1 KH domain-containing protein -
  EXW45_RS20100 (EXW45_20450) rpsP 3957509..3957781 (-) 273 WP_000268750.1 30S ribosomal protein S16 -
  EXW45_RS20105 (EXW45_20455) ffh 3957882..3959231 (-) 1350 WP_149293645.1 signal recognition particle protein -
  EXW45_RS20110 (EXW45_20460) - 3959244..3959576 (-) 333 WP_000891061.1 putative DNA-binding protein -
  EXW45_RS20115 (EXW45_20465) ftsY 3959710..3960699 (-) 990 WP_000007644.1 signal recognition particle-docking protein FtsY -
  EXW45_RS20120 (EXW45_20470) smc 3960715..3964284 (-) 3570 WP_097917878.1 chromosome segregation protein SMC -
  EXW45_RS20125 (EXW45_20475) rncS 3964432..3965169 (-) 738 WP_001146867.1 ribonuclease III -
  EXW45_RS20130 (EXW45_20480) acpP 3965228..3965461 (-) 234 WP_000786062.1 acyl carrier protein -
  EXW45_RS20135 (EXW45_20485) fabG 3965531..3966271 (-) 741 WP_097917877.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  EXW45_RS20140 (EXW45_20490) fabD 3966271..3967215 (-) 945 WP_000516944.1 ACP S-malonyltransferase -
  EXW45_RS20145 (EXW45_20495) plsX 3967230..3968222 (-) 993 WP_046956482.1 phosphate acyltransferase PlsX -
  EXW45_RS20150 (EXW45_20500) fapR 3968219..3968812 (-) 594 WP_000747354.1 transcription factor FapR -
  EXW45_RS20155 (EXW45_20505) recG 3968901..3970949 (-) 2049 WP_149293644.1 ATP-dependent DNA helicase RecG -
  EXW45_RS20160 (EXW45_20510) - 3971233..3972909 (-) 1677 WP_000027123.1 DAK2 domain-containing protein -
  EXW45_RS20165 (EXW45_20515) - 3972932..3973294 (-) 363 WP_000021109.1 Asp23/Gls24 family envelope stress response protein -
  EXW45_RS20170 (EXW45_20520) rpmB 3973670..3973858 (+) 189 WP_000124776.1 50S ribosomal protein L28 -
  EXW45_RS20175 (EXW45_20525) spoVM 3973932..3974012 (-) 81 WP_001213599.1 stage V sporulation protein SpoVM -
  EXW45_RS20180 (EXW45_20530) - 3974079..3974759 (-) 681 WP_002008369.1 thiamine diphosphokinase -
  EXW45_RS20185 (EXW45_20535) rpe 3974859..3975503 (-) 645 WP_149293643.1 ribulose-phosphate 3-epimerase -
  EXW45_RS20190 (EXW45_20540) rsgA 3975506..3976387 (-) 882 WP_001113945.1 ribosome small subunit-dependent GTPase A -

Sequence

Protein


Download         Length: 259 a.a.        Molecular weight: 28793.05 Da        Isoelectric Point: 4.7165

>NTDB_id=346485 EXW45_RS20020 WP_000421290.1 3942385..3943164(-) (codY) [Bacillus wiedmannii strain JAS08/1]
MELLAKTRKLNALLQSAAGKPVNFREMSDTMCEVIEANVFVVSRRGKLLGYAIHQQIENERMKQMLAERQFPEEYTQSLF
NITETSSNLDVNSAYTAFPVENRELFGQGLTTIVPIVGGGERLGTLVLARLGQEFLDDDLILAEYSSTVVGMEILREKAE
EIEEEARSKAVVQMAISSLSYSELEAIEHIFEELNGTEGLLVASKIADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
YIKVLNDKFLQELAKLKTN

Nucleotide


Download         Length: 780 bp        

>NTDB_id=346485 EXW45_RS20020 WP_000421290.1 3942385..3943164(-) (codY) [Bacillus wiedmannii strain JAS08/1]
ATGGAATTATTAGCAAAAACAAGAAAATTAAATGCGTTATTACAGAGCGCAGCAGGAAAGCCTGTAAACTTTAGAGAAAT
GTCTGACACAATGTGTGAAGTAATCGAAGCGAACGTATTCGTAGTAAGCCGTCGTGGTAAATTACTAGGTTATGCAATTC
ACCAACAAATTGAGAATGAGCGTATGAAACAAATGCTTGCAGAGCGTCAATTCCCGGAAGAATACACGCAAAGCTTATTC
AACATTACAGAAACATCTTCAAACTTAGATGTAAACAGTGCTTACACAGCATTCCCAGTAGAAAATAGAGAATTATTTGG
TCAAGGTTTAACTACAATCGTACCAATCGTTGGTGGCGGTGAGCGTCTAGGCACATTAGTGTTAGCTCGTCTTGGTCAAG
AGTTCTTAGACGATGATTTAATCCTTGCTGAATACAGTTCAACTGTAGTAGGTATGGAAATCTTACGTGAAAAAGCAGAA
GAAATCGAAGAGGAAGCACGTAGTAAAGCTGTTGTTCAAATGGCGATTAGCTCATTATCTTACAGTGAGTTAGAAGCAAT
CGAGCATATCTTCGAAGAATTAAATGGAACAGAAGGTTTACTTGTTGCAAGTAAAATTGCTGATCGCGTAGGAATTACTC
GTTCTGTAATCGTAAATGCACTTCGTAAATTAGAGAGTGCTGGTGTTATTGAGTCTCGCTCTTTAGGTATGAAAGGAACA
TACATTAAAGTGCTAAACGACAAGTTTCTACAGGAACTTGCTAAATTAAAAACAAACTAA

Domains

Predicted by InterproScan.

CodY GAF-like domain (CodY)

(2-178)

CodY helix-turn-helix domain (HTH_CodY)

(198-255)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  codY Bacillus subtilis subsp. subtilis str. 168

81.467

100

0.815
  codY Lactococcus lactis subsp. lactis strain DGCC12653

46.667

98.456

0.459

Multiple sequence alignment