Detailed information NTG0346471

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EXW45_RS06110
• Genome accession: NZ_CP036073
• Coordinates: 1190614..1193214 (+)
• Length: 866 a.a.
• NCBI ID: WP_046958316.1
• Uniprot ID: A0A0G8CDV2
• Organism: Bacillus wiedmannii strain JAS08/1
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1185614..1198214

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EXW45_RS06075 (EXW45_06145)	prsA	1186388..1187245 (-)	858	WP_149294164.1	peptidylprolyl isomerase PrsA	-
EXW45_RS06080 (EXW45_06150)	-	1187376..1187507 (-)	132	WP_001120852.1	DUF3941 domain-containing protein	-
EXW45_RS06085 (EXW45_06155)	-	1187608..1188465 (+)	858	WP_149294163.1	YitT family protein	-
EXW45_RS06090 (EXW45_06160)	-	1188491..1188688 (-)	198	WP_000527398.1	DUF3813 domain-containing protein	-
EXW45_RS06095 (EXW45_06165)	-	1188689..1188829 (-)	141	WP_000516816.1	hypothetical protein	-
EXW45_RS06100 (EXW45_06170)	-	1188934..1189743 (-)	810	WP_001041225.1	Cof-type HAD-IIB family hydrolase	-
EXW45_RS06105 (EXW45_06175)	-	1190236..1190415 (+)	180	WP_000531420.1	YjzC family protein	-
EXW45_RS06110 (EXW45_06180)	clpC	1190614..1193214 (+)	2601	WP_046958316.1	ATP-dependent chaperone ClpB	Regulator
EXW45_RS06115 (EXW45_06185)	-	1193251..1193433 (-)	183	WP_001211110.1	YjzD family protein	-
EXW45_RS06120 (EXW45_06190)	-	1193590..1194324 (+)	735	WP_000028707.1	hydrolase	-
EXW45_RS06125 (EXW45_06195)	-	1194354..1195226 (+)	873	WP_141545409.1	NAD(P)-dependent oxidoreductase	-
EXW45_RS06130 (EXW45_06200)	comZ	1195280..1195456 (+)	177	WP_001003337.1	ComZ family protein	Regulator
EXW45_RS06135 (EXW45_06205)	fabH	1195688..1196620 (+)	933	WP_097918337.1	beta-ketoacyl-ACP synthase III	-
EXW45_RS06140 (EXW45_06210)	fabF	1196652..1197890 (+)	1239	WP_000412646.1	beta-ketoacyl-ACP synthase II	-

Sequence

Protein

• Length: 866 a.a.
• Molecular weight: 97431.50 Da
• Isoelectric Point: 5.1540

>NTDB_id=346471 EXW45_RS06110 WP_046958316.1 1190614..1193214(+) (clpC) [Bacillus wiedmannii strain JAS08/1]
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLFTLLEEQDGLAVRIFQKMNVDIEALKQGVESLIKKKPSVTGSGAE
VGKLYITGALQQLLVRAGKEAEKLQDDYISVEHVLLAFSEEKGDINQLLTRFHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQLELSDLKEVASGMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNKAAELRHGKIPAIEKELKEAEEMGAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEADGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDAAREFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

Nucleotide

• Length: 2601 bp

>NTDB_id=346471 EXW45_RS06110 WP_046958316.1 1190614..1193214(+) (clpC) [Bacillus wiedmannii strain JAS08/1]
ATGGACTTAAATCAAATGACAACAAAAACACAAGAGGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCATCATCA
AGAAGTAGATACTGTTCATCTCTTATTTACATTATTAGAAGAGCAAGATGGGTTAGCAGTGCGTATTTTTCAAAAAATGA
ATGTCGATATAGAAGCGTTAAAGCAAGGCGTCGAAAGTTTAATTAAGAAAAAACCTTCTGTAACGGGAAGCGGTGCAGAA
GTAGGAAAATTATATATAACAGGTGCTCTGCAACAACTACTTGTAAGAGCAGGAAAAGAAGCAGAGAAATTGCAAGATGA
CTACATTTCAGTTGAACATGTATTGCTTGCTTTTTCAGAAGAAAAAGGCGATATAAATCAATTACTTACAAGATTTCACA
TTACGAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGTCGTGATTTAGTGGCGGAAGTGAGAGCAGGGAAAATTGATCCTGTTATCGGTCGCGA
TAGTGAAATTCGACGTGTAATCCGCATTCTTTCACGTAAAACGAAAAACAACCCGGTTTTAATTGGTGAACCCGGTGTTG
GTAAAACAGCAATCGTTGAAGGATTAGCACAGCGTATTGTGAAGAAGGATGTACCAGAAGGATTAAAAGATAGAACAATC
TTCGCATTAGATATGAGTGCGCTTGTAGCTGGAGCGAAATTCCGTGGTGAGTTTGAAGAGCGTCTGCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGTCGCATTTTATTATTCATTGATGAACTTCACACAATCGTCGGTGCTGGTAAAACAGAAG
GTGCGATGGACGCAGGAAATATGTTAAAACCGATGCTTGCGCGTGGTGAATTGCATTGTATCGGGGCGACAACGTTAGAT
GAGTATCGTAAATATATTGAGAAAGATCCAGCGCTAGAAAGACGTTTCCAACAAGTATTAGCAGAAGAACCAACTGTTGA
AGATACAATTTCCATTTTACGTGGTTTAAAAGAGCGCTTTGAAATTTATCATGGTGTAAATATTCATGACCGCGCGATTG
TAGCAGCATCCGTTTTATCAGATCGATATATTTCGGATCGTTTCTTACCAGATAAAGCGATTGATCTTGTTGACGAAGCG
TGCGCAACGATTCGAACAGAGATTGATTCTATGCCAACAGAATTAGATGAAGTAACGCGTCGTATTATGCAGCTGGAAAT
TGAAGAAGCGGCTCTTGGAAAAGAGAAGGACTTTGGTAGCCAAGAACGCCTGAAAACGTTGCAACTTGAATTGTCAGATT
TAAAAGAAGTTGCAAGTGGTATGAGAGCGAAATGGGAGAAAGAAAAAGAAGACATTCATAAAGTGCGTGACTTACGTGAA
CATTTAGAGCGCTTGCGCCGTGAGTTAGAAGAAGCAGAAGGAAATTACGATTTAAATAAAGCAGCTGAACTTCGTCACGG
GAAAATTCCAGCTATCGAAAAAGAGTTAAAAGAAGCGGAAGAAATGGGTGCACATAATAAACAAGAGAATCGCTTATTAC
GTGAGGAAGTAAGTGAAGAAGAGATTGCTGATATTGTTTCACGCTGGACTGGTATTCCTGTCGCAAAACTCGTTGAAGGT
GAACGCGAGAAATTACTACGCTTAGAGCAAATTTTATCAGAGCGTGTCATCGGACAAGAGGAAGCGGTAAGCTTAGTATC
AGACGCAGTTCTTCGTGCACGCGCTGGTATTAAAGACCCGAACCGTCCAATTGGTTCCTTCATCTTTTTAGGACCGACAG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCACAGTCTTTATTCGATAGTGAAGAGCAAATGATTCGTATCGACATG
TCTGAGTATATGGAGAAACACGCTGTGTCACGCTTAATTGGTGCGCCTCCTGGATATGTTGGGTATGAAGAGGGCGGTCA
ATTAACAGAAGCGGTAAGACGTAAACCGTATTCAGTTATTTTGTTAGACGAAATCGAAAAAGCACATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGATGGACGCATTACAGATTCGCAAGGACGTACAGTAGACTTTAAAAATACGGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTGTTAGATGGATTAGAAGCAGATGGCTCAATTAAAGAGGAATCAAGAGA
ACTTGTAATGGGGCAATTAAGAGGACATTTCCGACCAGAGTTTTTAAACCGTGTCGATGAAATTATTTTATTCAAACCTC
TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGTCGTTTAGCTGACCGTCATATTACA
GTAGAATTAACAGACGCAGCGAGAGAATTTGTTGTAGAAGCTGGCTTTGATCCGATGTACGGAGCTCGTCCATTAAAACG
ATATGTACAGCGTCAAGTTGAGACGAAATTAGCGAGAGAATTAATTGCAGGAACAATTACTGATAACAGTCACGTAGTTG
TTGATGTGGAAAATAACGAATTAGTCGTTCATGTAAAGTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (206-339)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (774-854)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-148)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• AAA lid domain (AAA_lid_9) (345-447)

• AAA domain (Cdc48 subfamily) (AAA_2) (602-768)

3D structure

• AlphaFold DB: A0A0G8CDV2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.657	100	0.482
clpC	Lactococcus lactis subsp. cremoris KW2	46.919	82.448	0.387
clpE	Streptococcus mutans UA159	46.016	84.065	0.387