Detailed information NTG0346273

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: EXW64_RS05835
• Genome accession: NZ_CP036052
• Coordinates: 1123787..1126387 (+)
• Length: 866 a.a.
• NCBI ID: WP_000365397.1
• Uniprot ID: A0A2B6H9B6
• Organism: Bacillus toyonensis strain JAS03/3
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1118787..1131387

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EXW64_RS05795 (EXW64_05915)	-	1118896..1119481 (+)	586	Protein_1053	hypothetical protein	-
EXW64_RS05800 (EXW64_05920)	prsA	1119550..1120407 (-)	858	WP_001214219.1	peptidylprolyl isomerase PrsA	-
EXW64_RS05805 (EXW64_05925)	-	1120537..1120668 (-)	132	WP_001120851.1	DUF3941 domain-containing protein	-
EXW64_RS05810 (EXW64_05930)	-	1120769..1121626 (+)	858	WP_000364440.1	YitT family protein	-
EXW64_RS05815 (EXW64_05935)	-	1121652..1121849 (-)	198	WP_000527396.1	DUF3813 domain-containing protein	-
EXW64_RS05820 (EXW64_05940)	-	1121850..1121990 (-)	141	WP_000516816.1	hypothetical protein	-
EXW64_RS05825 (EXW64_05945)	-	1122095..1122904 (-)	810	WP_000043171.1	Cof-type HAD-IIB family hydrolase	-
EXW64_RS05830 (EXW64_05950)	-	1123397..1123576 (+)	180	WP_002093816.1	YjzC family protein	-
EXW64_RS05835 (EXW64_05955)	clpC	1123787..1126387 (+)	2601	WP_000365397.1	ATP-dependent chaperone ClpB	Regulator
EXW64_RS05840 (EXW64_05960)	-	1126424..1126606 (-)	183	WP_001211112.1	YjzD family protein	-
EXW64_RS05845 (EXW64_05965)	-	1126763..1127497 (+)	735	WP_000028709.1	hypothetical protein	-
EXW64_RS05850 (EXW64_05970)	-	1127527..1128399 (+)	873	WP_000486174.1	NAD(P)-dependent oxidoreductase	-
EXW64_RS05855 (EXW64_05975)	comZ	1128464..1128640 (+)	177	WP_001003338.1	ComZ family protein	Regulator
EXW64_RS05860 (EXW64_05980)	fabH	1128885..1129817 (+)	933	WP_001100553.1	beta-ketoacyl-ACP synthase III	-
EXW64_RS05865 (EXW64_05985)	fabF	1129848..1131086 (+)	1239	WP_000412641.1	beta-ketoacyl-ACP synthase II	-

Sequence

Protein

• Length: 866 a.a.
• Molecular weight: 97611.62 Da
• Isoelectric Point: 5.1950

>NTDB_id=346273 EXW64_RS05835 WP_000365397.1 1123787..1126387(+) (clpC) [Bacillus toyonensis strain JAS03/3]
MDLNQMTTKTQEAIMSAQSLAVSHHHQEVDTVHLLLALLEEQDGLAVRIFQKMNVDIEALKQDVENVIKKKPSVTGSGAE
VGKLYITSNLQQLLVRAGKEAEKLQDDYISVEHVLLAFSEEKGDINHLFTRLHITKDNLLQSLMTVRGNQRVTSQNPEAT
YEALEKYGRDLVAEVRAGKIDPVIGRDSEIRRVIRILSRKTKNNPVLIGEPGVGKTAIVEGLAQRIVKKDVPEGLKDRTI
FALDMSALVAGAKFRGEFEERLQAVLNEIKKSEGRILLFIDELHTIVGAGKTEGAMDAGNMLKPMLARGELHCIGATTLD
EYRKYIEKDPALERRFQQVLAEEPTVEDTISILRGLKERFEIYHGVNIHDRAIVAASVLSDRYISDRFLPDKAIDLVDEA
CATIRTEIDSMPTELDEVTRRIMQLEIEEAALGKEKDFGSQERLKTLQRELSDLKEVASSMRAKWEKEKEDIHKVRDLRE
HLERLRRELEEAEGNYDLNKAAELRHGKIPAIEKELKEAEEMSAHNKQENRLLREEVSEEEIADIVSRWTGIPVAKLVEG
EREKLLRLEQILSERVIGQEEAVSLVSDAVLRARAGIKDPNRPIGSFIFLGPTGVGKTELAKTLAQSLFDSEEQMIRIDM
SEYMEKHAVSRLIGAPPGYVGYEEGGQLTEAVRRKPYSVILLDEIEKAHPEVFNILLQMLDDGRITDSQGRTVDFKNTVI
IMTSNIGSAHLLDGLEADGSIKEESRELVMGQLRGHFRPEFLNRVDEIILFKPLTTNEIKGIVDKIVKELQGRLADRHIT
VELTDSAKEFVVEAGFDPMYGARPLKRYVQRQVETKLARELIAGTITDNSHVVVDVENNELVVHVK

Nucleotide

• Length: 2601 bp

>NTDB_id=346273 EXW64_RS05835 WP_000365397.1 1123787..1126387(+) (clpC) [Bacillus toyonensis strain JAS03/3]
ATGGACTTAAATCAAATGACAACGAAAACACAAGAGGCGATTATGAGTGCCCAATCTTTAGCGGTATCTCATCATCACCA
AGAGGTGGATACTGTTCATCTATTACTTGCATTATTAGAGGAGCAAGATGGATTAGCAGTACGTATATTTCAAAAAATGA
ATGTTGATATAGAAGCATTGAAGCAAGATGTAGAAAATGTAATTAAAAAGAAACCTTCTGTAACGGGAAGCGGAGCAGAA
GTTGGGAAATTGTATATAACAAGCAATCTGCAGCAACTGCTTGTAAGAGCAGGGAAAGAAGCAGAAAAACTGCAGGATGA
TTACATTTCAGTAGAACATGTATTGCTTGCTTTTTCTGAAGAAAAAGGCGATATCAATCATTTATTTACAAGATTGCATA
TTACGAAAGATAACTTATTACAGTCTTTAATGACAGTTCGGGGGAATCAAAGAGTGACTAGTCAAAATCCAGAAGCAACT
TATGAAGCGTTAGAAAAATATGGCCGTGATTTAGTGGCGGAAGTGAGAGCAGGGAAAATTGATCCTGTTATCGGACGAGA
TAGTGAAATTCGCCGCGTTATTCGCATTCTTTCACGTAAAACGAAAAACAACCCTGTTTTAATTGGTGAGCCAGGTGTTG
GTAAAACAGCAATTGTTGAAGGATTAGCACAGCGTATCGTGAAAAAAGATGTACCAGAAGGGTTAAAAGATAGAACAATC
TTTGCATTAGATATGAGTGCACTTGTAGCCGGAGCAAAATTCCGTGGTGAATTTGAAGAGCGCCTGCAAGCTGTATTAAA
TGAAATTAAAAAGAGTGAAGGCCGTATTTTATTATTCATTGATGAACTTCATACAATCGTCGGTGCTGGTAAAACAGAAG
GTGCGATGGACGCAGGGAATATGTTAAAACCGATGCTTGCTCGTGGTGAACTGCATTGTATCGGGGCAACGACATTAGAT
GAATATCGTAAATATATTGAGAAAGACCCAGCGTTAGAAAGACGTTTCCAACAAGTATTAGCAGAGGAACCGACTGTTGA
AGATACAATCTCCATTTTACGTGGTTTAAAAGAGCGTTTTGAAATTTATCACGGTGTAAATATTCATGACCGCGCGATTG
TAGCAGCATCTGTTTTATCAGATCGATATATTTCAGATCGCTTCTTACCGGATAAAGCAATTGACCTTGTTGACGAAGCG
TGCGCAACAATTCGTACAGAAATTGATTCTATGCCAACAGAATTAGATGAAGTAACGCGCCGTATTATGCAGCTGGAAAT
TGAAGAAGCCGCTCTTGGAAAAGAGAAGGACTTTGGTAGCCAAGAACGTCTGAAAACATTGCAACGTGAATTATCGGATT
TAAAAGAAGTTGCAAGTAGCATGAGAGCGAAATGGGAGAAAGAAAAAGAAGATATTCACAAAGTTCGTGACTTACGTGAA
CATTTAGAGCGTCTGCGCCGTGAATTAGAAGAAGCAGAAGGTAATTACGATTTAAATAAAGCAGCTGAACTTCGTCACGG
AAAAATTCCTGCAATTGAAAAAGAATTAAAAGAAGCGGAAGAAATGAGCGCACATAATAAACAAGAAAATCGTTTATTAC
GCGAGGAAGTCAGTGAAGAAGAAATTGCTGATATCGTTTCACGCTGGACTGGTATTCCTGTCGCAAAACTCGTTGAGGGT
GAACGTGAGAAATTACTACGCTTAGAGCAAATTTTATCAGAGCGTGTCATCGGACAAGAGGAAGCGGTAAGTTTAGTATC
AGACGCAGTTCTTCGTGCACGCGCTGGTATTAAAGACCCGAACCGTCCAATTGGTTCCTTCATTTTCTTAGGACCGACAG
GTGTTGGTAAAACAGAACTTGCAAAAACGTTAGCGCAGTCTTTATTCGATAGTGAAGAGCAAATGATTCGCATCGACATG
TCTGAGTACATGGAGAAACATGCTGTGTCACGCTTAATTGGTGCACCTCCTGGATATGTTGGATATGAAGAGGGCGGTCA
ATTAACGGAAGCAGTAAGACGTAAACCGTATTCCGTTATTTTGTTAGACGAAATCGAAAAAGCGCATCCAGAAGTATTCA
ACATTTTATTACAAATGTTAGATGATGGACGCATTACAGATTCGCAAGGACGTACAGTAGACTTTAAAAACACGGTTATT
ATTATGACTTCAAATATTGGATCTGCTCATTTATTAGATGGATTAGAAGCAGATGGTTCCATTAAAGAGGAATCAAGAGA
ACTTGTCATGGGACAATTAAGAGGACATTTCCGACCAGAGTTTTTAAATCGTGTCGATGAAATTATTTTATTCAAGCCTC
TTACAACGAATGAAATTAAAGGTATTGTTGATAAAATTGTAAAAGAATTACAAGGTCGTTTAGCTGACCGTCATATTACG
GTAGAATTAACGGATTCTGCAAAAGAATTTGTTGTAGAAGCTGGCTTTGATCCGATGTACGGAGCTCGTCCATTAAAACG
ATACGTACAGCGTCAAGTGGAAACGAAATTAGCGAGAGAATTAATTGCAGGCACAATTACGGATAATAGTCACGTAGTTG
TTGATGTAGAAAATAACGAATTAGTTGTTCATGTGAAATGA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (602-768)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (774-854)

• AAA lid domain (AAA_lid_9) (345-447)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (97-148)

• ATPase family associated with various cellular activities (AAA) (AAA) (206-339)

3D structure

• AlphaFold DB: A0A2B6H9B6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	47.657	100	0.482
clpC	Lactococcus lactis subsp. cremoris KW2	46.704	82.333	0.385