Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   GII90_RS20575 Genome accession   NZ_CP045811
Coordinates   3995019..3996221 (-) Length   400 a.a.
NCBI ID   WP_009969578.1    Uniprot ID   P39668
Organism   Bacillus subtilis strain P9_B1     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3990019..4001221
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GII90_RS20550 (GII90_20550) rocE 3990127..3991530 (-) 1404 WP_003242721.1 amino acid permease -
  GII90_RS20555 (GII90_20555) rocD 3991753..3992958 (-) 1206 WP_153940279.1 ornithine aminotransferase -
  GII90_RS20560 (GII90_20560) rocR 3993199..3994584 (+) 1386 WP_003244510.1 arginine utilization regulatory protein RocR -
  GII90_RS20565 (GII90_20565) - 3994566..3994754 (-) 189 Protein_4006 ATP-binding protein -
  GII90_RS20570 (GII90_20570) - 3994871..3994999 (-) 129 WP_003242634.1 hypothetical protein -
  GII90_RS20575 (GII90_20575) htrA 3995019..3996221 (-) 1203 WP_009969578.1 serine protease HtrC Regulator
  GII90_RS20580 (GII90_20580) vicX 3996303..3997097 (-) 795 WP_003242676.1 MBL fold metallo-hydrolase Regulator
  GII90_RS20585 (GII90_20585) walI 3997119..3997961 (-) 843 WP_003244037.1 WalRK two-component regulatory system regulator WalI -
  GII90_RS20590 (GII90_20590) walH 3997948..3999315 (-) 1368 WP_003242498.1 WalRK two-component regulatory system regulator WalH -
  GII90_RS20595 (GII90_20595) walK 3999305..4001140 (-) 1836 WP_009968432.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42788.56 Da        Isoelectric Point: 5.3354

>NTDB_id=346273 GII90_RS20575 WP_009969578.1 3995019..3996221(-) (htrA) [Bacillus subtilis strain P9_B1]
MVDYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGALDQQQNNNGRESIRTVNVSVNNAVTK
IVSNMSPAVVGVVNIQKSDIWGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVSADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWDETLKLPK
NVTNGAVVMGVDAFSPAGKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDRVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=346273 GII90_RS20575 WP_009969578.1 3995019..3996221(-) (htrA) [Bacillus subtilis strain P9_B1]
ATGGTGGATTACGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
CCTTAGATCAGCAGCAAAACAACAATGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATATGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTGGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCTGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGCTCACGTGTATCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCCGTTTTACGGGTGAAAAGCGATAAGATTAAAGCAGTCGCTGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCAGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCTGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCAGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCGCTAAGTGACATCGCAAGCTATCATTGGGATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGCGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGGAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACC
GGGTGAAGGTGAAGTTTTATCGCGGCGGAAAAGAAAAATCTGTTGATATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

PDZ domain (PDZ_2)

(295-392)

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(203-395)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P39668

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.577

99.25

0.433
  htrA Streptococcus gordonii str. Challis substr. CH1

41.294

100

0.415
  htrA Streptococcus mitis NCTC 12261

42.746

96.5

0.412
  htrA Streptococcus pneumoniae TIGR4

44.848

82.5

0.37
  htrA Streptococcus pneumoniae D39

44.848

82.5

0.37
  htrA Streptococcus pneumoniae Rx1

44.848

82.5

0.37
  htrA Streptococcus pneumoniae R6

44.848

82.5

0.37

Multiple sequence alignment