Detailed information NTG0034627

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SSU_RS07520
• Genome accession: NC_012925
• Coordinates: 1506945..1507994 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis P1/7
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1501945..1512994

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSU_RS07500 (SSU1486)	nadE	1502351..1503175 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
SSU_RS07505 (SSU1487)	-	1504471..1504998 (-)	528	WP_012027591.1	VanZ family protein	-
SSU_RS07510 (SSU1488)	rlmN	1504995..1506107 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SSU_RS07515 (SSU1489)	-	1506116..1506757 (-)	642	WP_012027595.1	YutD family protein	-
SSU_RS07520 (SSU1490)	sepM	1506945..1507994 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
SSU_RS07525 (SSU1491)	coaD	1507981..1508469 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
SSU_RS07530 (SSU1492)	rsmD	1508459..1508998 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SSU_RS07535 (SSU1493)	-	1509306..1510028 (-)	723	WP_012027598.1	lipoprotein	-
SSU_RS07540 (SSU1494)	-	1510085..1510471 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
SSU_RS07545 (SSU1495)	-	1510471..1510689 (-)	219	WP_004194736.1	YqgQ family protein	-
SSU_RS07550 (SSU1496)	-	1510997..1511599 (-)	603	WP_012027601.1	response regulator transcription factor	-
SSU_RS07555 (SSU1497)	-	1511596..1512690 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=34627 SSU_RS07520 WP_012775295.1 1506945..1507994(-) (sepM) [Streptococcus suis P1/7]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=34627 SSU_RS07520 WP_012775295.1 1506945..1507994(-) (sepM) [Streptococcus suis P1/7]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605