Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   EXW49_RS05970 Genome accession   NZ_CP036023
Coordinates   1184746..1186572 (+) Length   608 a.a.
NCBI ID   WP_002140837.1    Uniprot ID   A0A2A7ZGK4
Organism   Bacillus mycoides strain BPN52/2     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1179746..1191572
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EXW49_RS05950 (EXW49_06070) - 1179957..1180631 (-) 675 WP_002011349.1 TerC family protein -
  EXW49_RS05955 (EXW49_06075) mecA 1181068..1181751 (+) 684 WP_002030378.1 adaptor protein MecA Regulator
  EXW49_RS05960 (EXW49_06080) - 1181824..1183368 (+) 1545 WP_002064255.1 cardiolipin synthase -
  EXW49_RS05965 (EXW49_06085) - 1183460..1184695 (+) 1236 WP_215588824.1 competence protein CoiA family protein -
  EXW49_RS05970 (EXW49_06090) pepF 1184746..1186572 (+) 1827 WP_002140837.1 oligoendopeptidase F Regulator
  EXW49_RS05975 - 1186705..1186878 (-) 174 WP_002086970.1 hypothetical protein -
  EXW49_RS05980 (EXW49_06095) - 1187110..1188003 (-) 894 WP_002030386.1 ClpXP adapter SpxH family protein -
  EXW49_RS05985 (EXW49_06100) - 1188003..1188401 (-) 399 WP_000043388.1 hypothetical protein -
  EXW49_RS05990 (EXW49_06105) - 1188587..1189165 (-) 579 WP_002030388.1 CYTH domain-containing protein -
  EXW49_RS05995 (EXW49_06110) - 1189310..1189681 (+) 372 WP_002030390.1 hypothetical protein -
  EXW49_RS06000 (EXW49_06115) - 1189712..1190350 (+) 639 WP_002125951.1 GTP pyrophosphokinase family protein -
  EXW49_RS06005 (EXW49_06120) - 1190369..1191166 (+) 798 WP_002011365.1 NAD kinase -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 70301.71 Da        Isoelectric Point: 4.6710

>NTDB_id=345975 EXW49_RS05970 WP_002140837.1 1184746..1186572(+) (pepF) [Bacillus mycoides strain BPN52/2]
MAEKNTVKSLPNRNEIEEASTWRLEDIFQTDAEWEKEFQAIKELLPKLTEFKGKLGDSADNLLEALQYEDEISMRLGKLY
TYAHMRYDQDTTNSVYQALNDRATNLYSQVSSSTAYIVPEILSISEDTLQTFLQENRELSVYEHALEEITRQRPHVLSEA
EEALLAEASEVMSASSNTFGMLNNADLKFPSIKGEDGEEVEITHGRYIQFLESDDRRVREDAFKAVFETYGKFKNTFAST
LSGAVKRNNFNARIRKYDSARQAALSNNNIPEAVYDQLVETVNDNLHLLHRYIDIRKRALGLDELHMYDLYTPLVQEVKM
NVKYEEAQDLLLKSLNVLGDEYVEILKEAYENRWVDVYENKGKRSGAYSSGAYGTNPYILMNWHDNVNNLYTLAHEFGHS
VHSYYTRKTQPHVYGDYSIFVAEVASTCNEALLNDYLLKTTEDKKERLYLLNHYLEGFRGTVFRQTMFAEFEHIIHKKVQ
EGHAVTPDMLTEIYYDLNKKYFGDALVIDKEIGLEWSRIPHFYYNYYVYQYATGFSAATALSKQILEEGQPAVERYINEF
LKAGSSDYPIEVLKKAGVDMASPEPVKEALQVFEEKLNELEALLFEEK

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=345975 EXW49_RS05970 WP_002140837.1 1184746..1186572(+) (pepF) [Bacillus mycoides strain BPN52/2]
ATGGCTGAAAAAAATACAGTAAAATCATTACCAAATCGCAATGAGATTGAAGAAGCAAGCACATGGCGATTAGAAGATAT
TTTCCAAACAGATGCAGAATGGGAAAAAGAATTCCAAGCTATTAAAGAGCTATTGCCAAAGTTAACTGAATTTAAAGGGA
AGCTTGGCGACTCTGCAGACAATTTGCTTGAGGCATTGCAATATGAAGATGAAATTTCAATGCGATTAGGTAAGCTATAT
ACATATGCACATATGCGTTACGATCAAGATACAACAAACTCTGTGTATCAAGCACTGAATGATCGCGCAACAAATTTATA
CTCACAAGTATCTAGTAGCACAGCGTATATCGTACCTGAAATTTTATCTATTTCAGAAGATACATTGCAAACATTCTTAC
AAGAAAATCGAGAACTAAGTGTATATGAGCATGCATTAGAAGAAATTACACGTCAACGCCCGCACGTATTATCTGAGGCA
GAGGAAGCGTTATTAGCAGAAGCATCTGAAGTGATGAGTGCATCAAGTAATACATTCGGTATGTTGAATAATGCGGATTT
GAAATTCCCATCTATTAAAGGTGAGGATGGAGAAGAGGTAGAAATAACACATGGCCGTTACATTCAGTTTTTAGAAAGTG
ATGATCGTCGTGTTCGCGAAGATGCATTCAAAGCTGTATTTGAAACGTATGGGAAATTTAAGAACACATTTGCAAGTACG
TTAAGCGGGGCAGTGAAACGTAATAATTTCAATGCACGTATTCGTAAATATGACTCTGCTCGCCAAGCAGCATTAAGCAA
TAATAATATTCCTGAAGCAGTATACGATCAACTCGTTGAAACGGTAAATGACAACTTACATTTATTACACCGTTACATTG
ATATTCGTAAGCGTGCACTAGGACTTGATGAGCTTCATATGTACGATTTATATACACCACTTGTACAAGAAGTGAAAATG
AATGTGAAGTATGAAGAAGCGCAAGACCTGTTATTAAAATCTTTAAACGTACTTGGTGATGAATATGTTGAAATTTTAAA
AGAAGCATATGAAAATCGCTGGGTAGATGTGTACGAGAATAAAGGCAAACGAAGCGGAGCATATTCATCTGGTGCATACG
GAACAAATCCGTATATTTTAATGAACTGGCATGATAATGTAAATAATTTATATACACTTGCTCATGAGTTTGGTCATTCG
GTGCATAGTTATTACACAAGAAAGACACAGCCACACGTATACGGTGATTATTCAATCTTCGTTGCAGAGGTAGCATCAAC
TTGTAATGAAGCGCTTCTAAATGATTATTTATTAAAAACGACAGAAGATAAAAAAGAGCGTCTATATTTATTAAATCATT
ATTTAGAAGGATTCCGTGGTACTGTATTCCGTCAAACAATGTTTGCAGAGTTCGAGCATATCATTCATAAAAAAGTACAA
GAAGGACATGCGGTTACGCCAGATATGTTAACGGAGATCTACTACGATTTAAATAAGAAATATTTCGGGGATGCTTTAGT
AATCGATAAAGAAATCGGTTTAGAATGGTCTCGTATTCCGCACTTCTATTACAACTATTACGTATATCAATACGCAACAG
GATTTAGTGCAGCGACTGCGTTATCTAAACAAATTTTAGAAGAAGGGCAACCAGCAGTAGAACGTTACATTAACGAATTC
TTAAAAGCGGGAAGCTCCGATTATCCAATTGAAGTGTTGAAAAAAGCAGGAGTTGATATGGCATCTCCTGAACCAGTGAA
AGAGGCACTTCAAGTATTTGAAGAGAAATTAAATGAATTAGAAGCGTTATTATTTGAAGAAAAGTAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(120-189)

Peptidase family M3 (Peptidase_M3)

(211-591)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2A7ZGK4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

49.916

97.533

0.487

Multiple sequence alignment