Detailed information NTG0345838

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: EXW40_RS20180
• Genome accession: NZ_CP036009
• Coordinates: 3969814..3970608 (-)
• Length: 264 a.a.
• NCBI ID: WP_002015081.1
• Uniprot ID: R8I3Q7
• Organism: Bacillus mycoides strain BPN43/2
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 3964814..3975608

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EXW40_RS20160 (EXW40_20565)	-	3964986..3966047 (-)	1062	WP_215586834.1	hypothetical protein	-
EXW40_RS20165 (EXW40_20570)	-	3967060..3967527 (-)	468	WP_098271184.1	hypothetical protein	-
EXW40_RS20170 (EXW40_20575)	-	3967591..3967860 (-)	270	WP_215586835.1	hypothetical protein	-
EXW40_RS20175 (EXW40_20580)	-	3968677..3969648 (-)	972	WP_215586836.1	tyrosine-type recombinase/integrase	-
EXW40_RS20180 (EXW40_20585)	spo0A	3969814..3970608 (-)	795	WP_002015081.1	sporulation transcription factor Spo0A	Regulator
EXW40_RS20185 (EXW40_20595)	spoIVB	3970895..3972187 (-)	1293	WP_113769229.1	SpoIVB peptidase	-
EXW40_RS20190 (EXW40_20600)	recN	3972307..3974046 (-)	1740	WP_002088564.1	DNA repair protein RecN	Machinery gene
EXW40_RS20195 (EXW40_20605)	argR	3974317..3974766 (-)	450	WP_002015076.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29525.32 Da
• Isoelectric Point: 7.1180

>NTDB_id=345838 EXW40_RS20180 WP_002015081.1 3969814..3970608(-) (spo0A) [Bacillus mycoides strain BPN43/2]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGIAYNGQECLNLLKEKQPDILVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKESATIKRPLPSFRSATTIDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=345838 EXW40_RS20180 WP_002015081.1 3969814..3970608(-) (spo0A) [Bacillus mycoides strain BPN43/2]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTGGTATCGATGCTAGAGAGTTATGTTGCTGCCCAAGA
TGATATGGAAGTTATCGGAATTGCTTACAATGGTCAAGAATGTTTAAACTTATTGAAAGAAAAGCAGCCTGATATACTCG
TTTTAGACATTATTATGCCACATTTAGATGGTCTAGCTGTGCTAGAGAAAATGCGACATATTGAAAGGTTAAGACAACCT
AGCGTTATTATGTTGACAGCATTCGGACAAGAAGATGTGACGAAAAAAGCGGTTGATTTAGGGGCATCATATTTCATATT
AAAACCATTTGATATGGAGAATTTAACAAGTCATATTCGTCAAGTTAGTGGTAAGGAAAGTGCTACTATTAAACGTCCAT
TACCATCTTTCCGATCAGCAACAACGATAGATGGAAAACCGAAAAACTTAGATGCGAGTATTACAAGTATCATTCATGAA
ATTGGTGTACCCGCTCATATTAAAGGGTACATGTACTTACGAGAAGCGATCTCTATGGTGTACAATGATATCGAATTACT
AGGATCTATTACGAAAGTATTATATCCAGATATTGCAAAGAAATATAATACAACAGCAAGCCGTGTCGAGCGCGCAATCC
GTCACGCAATTGAAGTAGCTTGGAGCCGTGGGAATATTGATTCTATTTCGTCCTTATTTGGTTATACTGTATCCATGTCA
AAAGCAAAACCTACGAATTCCGAGTTCATCGCAATGGTTGCGGATAAGCTAAGACTTGAACATAAGGCTTCGTAA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: R8I3Q7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818