Detailed information NTG0345276

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: EXW58_RS19275
• Genome accession: NZ_CP035953
• Coordinates: 3766322..3767116 (-)
• Length: 264 a.a.
• NCBI ID: WP_002111741.1
• Uniprot ID: J8E5N5
• Organism: Bacillus mycoides strain BPN03/1
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	3767439..3768748	3766322..3767116	flank	323

Gene organization within MGE regions

Location: 3766322..3768748

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EXW58_RS19275 (EXW58_19545)	spo0A	3766322..3767116 (-)	795	WP_002111741.1	sporulation transcription factor Spo0A	Regulator

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29579.37 Da
• Isoelectric Point: 7.1180

>NTDB_id=345276 EXW58_RS19275 WP_002111741.1 3766322..3767116(-) (spo0A) [Bacillus mycoides strain BPN03/1]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGIAYNGQECLNLLKEKQPDILVLDIIMPHLDGLAVLEKMRHIERLRQP
NVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKENATIKRPLPSFRSATTIDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=345276 EXW58_RS19275 WP_002111741.1 3766322..3767116(-) (spo0A) [Bacillus mycoides strain BPN03/1]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTGGTATCGATGCTAGAGAGCTATGTTGCTGCTCAGGA
TGATATGGAAGTTATTGGAATTGCTTACAATGGTCAAGAATGTTTAAACTTATTGAAAGAAAAGCAGCCTGATATACTCG
TTTTAGACATTATTATGCCACATTTAGATGGTCTAGCTGTGCTAGAGAAAATGCGACATATTGAAAGGTTAAGACAACCT
AACGTTATTATGTTGACAGCATTCGGACAAGAAGATGTGACGAAAAAAGCGGTTGATTTAGGGGCATCATATTTCATATT
AAAACCATTTGATATGGAGAATTTAACAAGTCATATTCGTCAAGTTAGTGGTAAGGAAAATGCTACCATTAAACGTCCAT
TACCATCTTTCCGATCAGCAACAACGATTGATGGCAAACCGAAAAACTTAGATGCGAGTATTACAAGTATCATTCATGAA
ATTGGTGTACCCGCTCATATTAAAGGATATATGTACTTACGAGAAGCAATCTCTATGGTGTACAATGATATCGAATTACT
AGGATCTATTACGAAAGTATTATATCCAGATATCGCAAAGAAATATAATACAACAGCAAGTCGTGTCGAGCGCGCAATCC
GTCACGCAATTGAAGTAGCTTGGAGCCGTGGGAATATTGATTCTATTTCGTCCTTATTTGGTTATACTGTATCCATGTCA
AAAGCAAAACCTACGAATTCCGAGTTCATCGCAATGGTTGCGGATAAGCTAAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (6-119)

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

3D structure

• AlphaFold DB: J8E5N5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818