Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   APAC_RS04135 Genome accession   NZ_CP035928
Coordinates   808075..809922 (-) Length   615 a.a.
NCBI ID   WP_130232917.1    Uniprot ID   A0A5C2HB29
Organism   Malaciobacter pacificus strain LMG 26638     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 803075..814922
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  APAC_RS04110 (APAC_0818) - 804348..804974 (-) 627 WP_130232912.1 adenylate kinase -
  APAC_RS04115 (APAC_0819) - 805123..805707 (+) 585 WP_130232913.1 adenylate kinase -
  APAC_RS04120 (APAC_0820) - 805704..806459 (+) 756 WP_130232914.1 competence/damage-inducible protein A -
  APAC_RS04125 (APAC_0821) - 806460..807050 (-) 591 WP_130232915.1 tetratricopeptide repeat protein -
  APAC_RS04130 (APAC_0822) - 807050..808072 (-) 1023 WP_130232916.1 alanine racemase -
  APAC_RS04135 (APAC_0823) uvrC 808075..809922 (-) 1848 WP_130232917.1 excinuclease ABC subunit UvrC Machinery gene
  APAC_RS04140 (APAC_0824) - 810010..810585 (+) 576 WP_130232918.1 SOS response-associated peptidase -
  APAC_RS04145 (APAC_0825) - 810597..811091 (-) 495 WP_130234576.1 glutathione peroxidase -
  APAC_RS04150 (APAC_0826) - 811218..812000 (-) 783 WP_130232919.1 TPR end-of-group domain-containing protein -
  APAC_RS04155 (APAC_0827) - 812115..813488 (-) 1374 WP_130232920.1 aspartate kinase -
  APAC_RS04160 (APAC_0828) - 813481..814134 (-) 654 WP_130232921.1 winged helix-turn-helix transcriptional regulator -
  APAC_RS04165 (APAC_0829) - 814136..814531 (-) 396 WP_130232922.1 ectoine synthase -

Sequence

Protein


Download         Length: 615 a.a.        Molecular weight: 72199.34 Da        Isoelectric Point: 9.2357

>NTDB_id=345103 APAC_RS04135 WP_130232917.1 808075..809922(-) (uvrC) [Malaciobacter pacificus strain LMG 26638]
MNLEEKLKQLPTDAGVYQYFDRNGHLLYIGKAKVLKNRVKSYFKFTPKLLPADKLSPRIYKMISEVESLEWIVVPNEHDA
LILENSLIKQLKPKYNILLRDDKTYPYIYLDNNELFPRLEITRRVYKNKNLKYFGPYSSGARDMLDSIYEIVPLVQKKSC
VKEKKACLFHQIKRCHAPCEGKITTSEYAKIVDEALEYIYNKTKLINKLNEKMMQYSEDFRFEDAMKIRDRIKTIEKSQI
KSGMDLATNEDIDIFAITTSNKKAVVVRMFIRDGKLTSSNHDFLRLDNIEQDSDFDYEEAYKRAIINYYDNEIPLLPKEI
LTAIDLEDKEELEDFLKARFDRKIKIINPKKDKKKDIVQVAINNCNELLRIDASKNQTTIYDEVKKLFDLKLTPYLIESF
DNSHMMGQATVGAMVVWNEQTNGWNKKSFRHYNLESKDEYSQMREMLMRRVESFEKNPAPDLWVIDGGETLLKLAYDITQ
SVGVNLDIIAIAKEKVDAKAHRAKGKANDIIHYKKDGEFKSLKLLTSDQRLQFVQRLRDEAHRFVINYHKKQKRKEDKQV
SLLQIKGIGEAKVKKMLLYFGEFEKIKSASIEELKNVLNEKDATVIYNYFNNIEE

Nucleotide


Download         Length: 1848 bp        

>NTDB_id=345103 APAC_RS04135 WP_130232917.1 808075..809922(-) (uvrC) [Malaciobacter pacificus strain LMG 26638]
ATGAATTTAGAAGAGAAATTAAAACAACTTCCCACTGATGCAGGAGTATATCAATACTTTGACAGAAATGGTCACTTACT
ATATATTGGAAAAGCAAAAGTACTTAAAAATAGAGTAAAATCTTACTTTAAATTTACTCCAAAACTATTACCTGCTGATA
AACTAAGTCCTCGTATATATAAAATGATTAGCGAAGTTGAATCTTTAGAGTGGATTGTAGTTCCTAATGAACATGATGCT
TTAATACTTGAAAATTCACTAATCAAACAACTAAAACCTAAATACAATATTTTATTAAGGGATGATAAAACATACCCATA
TATTTATTTAGATAACAATGAACTTTTTCCTAGACTTGAAATAACAAGACGTGTTTATAAAAATAAAAATCTAAAATATT
TTGGACCATATTCAAGTGGTGCTAGAGATATGTTAGATAGTATTTATGAAATTGTTCCTTTAGTTCAAAAGAAATCTTGT
GTAAAAGAGAAAAAAGCATGTCTTTTTCACCAAATAAAAAGATGCCATGCACCTTGTGAAGGTAAAATTACAACAAGTGA
GTATGCAAAAATTGTTGATGAAGCCTTAGAATATATTTACAACAAAACTAAACTAATTAATAAACTAAATGAAAAAATGA
TGCAATATTCAGAAGATTTTAGATTTGAAGATGCTATGAAAATAAGAGATAGAATAAAAACTATTGAAAAATCTCAAATT
AAATCAGGAATGGATTTAGCCACAAATGAAGATATTGATATTTTTGCAATAACAACATCTAATAAAAAAGCAGTTGTTGT
AAGAATGTTTATTAGAGATGGGAAGCTAACTTCATCAAACCATGACTTCTTAAGACTTGATAATATTGAGCAAGATAGTG
ATTTTGATTATGAAGAAGCATATAAAAGAGCTATTATTAATTATTATGATAATGAAATCCCACTACTTCCCAAAGAGATT
TTAACCGCAATTGACCTTGAAGATAAAGAAGAGCTTGAAGATTTTTTAAAAGCAAGATTTGATAGAAAAATAAAAATTAT
AAATCCTAAAAAAGATAAGAAAAAAGATATTGTACAAGTTGCAATTAATAACTGTAATGAACTGCTTAGAATCGATGCTA
GTAAAAATCAAACTACAATTTATGATGAAGTTAAAAAACTGTTTGACCTTAAACTTACTCCTTATTTAATAGAGAGTTTT
GATAACTCTCATATGATGGGTCAAGCAACTGTTGGAGCAATGGTTGTATGGAATGAACAAACTAATGGTTGGAATAAAAA
ATCTTTTAGACACTATAATCTTGAATCAAAAGATGAATATTCTCAAATGAGAGAGATGTTAATGAGAAGAGTTGAAAGTT
TTGAAAAAAATCCTGCACCTGATCTTTGGGTAATTGATGGAGGAGAAACCTTACTAAAACTTGCATATGATATAACTCAG
TCTGTGGGAGTTAATTTAGATATAATTGCCATAGCAAAAGAGAAAGTTGATGCAAAAGCACATAGAGCAAAAGGTAAAGC
AAATGACATTATTCACTACAAAAAAGATGGTGAATTTAAATCTTTAAAACTATTAACAAGTGACCAAAGGCTTCAATTTG
TTCAAAGACTTAGAGATGAAGCTCATAGGTTTGTAATTAACTATCATAAAAAACAAAAAAGAAAAGAAGATAAACAAGTT
TCACTTTTACAAATTAAAGGTATTGGTGAAGCAAAGGTGAAAAAAATGTTGCTATACTTTGGTGAATTTGAGAAAATAAA
AAGTGCATCTATTGAAGAATTAAAAAATGTTTTAAATGAAAAAGATGCAACTGTTATATATAATTATTTTAATAATATTG
AGGAATAA

Domains

Predicted by InterproScan.

GIY-YIG catalytic domain (GIY-YIG)

(15-96)

UvrB/uvrC motif (UVR)

(204-237)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(386-546)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5C2HB29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

50.498

97.886

0.494

Multiple sequence alignment