Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   ATH_RS03215 Genome accession   NZ_CP035926
Coordinates   599571..601427 (-) Length   618 a.a.
NCBI ID   WP_066184856.1    Uniprot ID   A0A1C0B442
Organism   Aliarcobacter thereius LMG 24486     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 594571..606427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ATH_RS03200 (ATH_0637) - 595062..596222 (-) 1161 WP_066184853.1 MalY/PatB family protein -
  ATH_RS03205 (ATH_0638) - 596236..598485 (-) 2250 WP_066184854.1 methyl-accepting chemotaxis protein -
  ATH_RS03210 (ATH_0639) - 598568..599593 (-) 1026 WP_066184855.1 alanine racemase -
  ATH_RS03215 (ATH_0640) uvrC 599571..601427 (-) 1857 WP_066184856.1 excinuclease ABC subunit UvrC Machinery gene
  ATH_RS03220 (ATH_0641) - 601578..603986 (+) 2409 WP_066187613.1 methyl-accepting chemotaxis protein -
  ATH_RS03225 (ATH_0642) - 604097..605524 (+) 1428 WP_066184858.1 catalase -
  ATH_RS03230 (ATH_0643) - 605526..606002 (+) 477 WP_066184859.1 ankyrin repeat domain-containing protein -

Sequence

Protein


Download         Length: 618 a.a.        Molecular weight: 72262.62 Da        Isoelectric Point: 9.2540

>NTDB_id=345070 ATH_RS03215 WP_066184856.1 599571..601427(-) (uvrC) [Aliarcobacter thereius LMG 24486]
MNLEEKLKQLPNQAGVYQYFDQNGHLLYIGKAKNLKNRVKSYFRFTPKLEANIDLSPRIFKMISETISLEWIIVPNEHDA
LILENSLIKQLKPKYNVLLRDDKTYPYIYVDLNEDFPRLEITRKIEKGKNIKYFGPYSSGAKDMLDSIYEIIPLVQKKSC
IKSNKACLFFQIGKCLAPCEDKIDKKDYKKLLDDALTYIYNKSKLINKLKEKMEFYSNNFRFEEALNIRDRIKTIEKSQI
KTAIDLTTNDDLDIFAIKFSSRKAVLVKMFIRDGKLASSSYDFIKMSSDLEFDLEEAYKRSIINYYSNELPIVPKEILLA
DEILELEDIEDFLQKKFNKKIKIINPKIDKKASIIKIALNNCDELLRLENLKDENSIYRDIKELFSLSVEPNYIEVFDNS
HFMGQARVGGMIVWDKELESFNKKEYRNYNLESLDEYSQMKEVLYRRVESFSKSSPPDLWIIDGGSTLLKLAFEIVSSIG
VNLDIIAISKQKVDAKAYRAKGNAKDIVHFKQNKEIKSLALLTSDKRLQFIQRLRDEAHRFAISFHKKQKRKEDKEISLL
QIKGIGEAKIKKLLLYFGEFQKIRDASFEDLKSVLNEKDAENLIEYFTKEKSGEDSTR

Nucleotide


Download         Length: 1857 bp        

>NTDB_id=345070 ATH_RS03215 WP_066184856.1 599571..601427(-) (uvrC) [Aliarcobacter thereius LMG 24486]
ATGAATTTAGAAGAAAAACTAAAACAACTTCCTAATCAAGCAGGAGTTTATCAATATTTTGATCAAAATGGACATCTTTT
ATATATTGGAAAAGCTAAGAATCTAAAAAATAGAGTTAAAAGCTATTTTAGGTTTACTCCTAAATTAGAAGCAAATATAG
ATTTAAGTCCAAGAATTTTTAAAATGATTAGTGAAACTATATCTTTAGAGTGGATTATTGTTCCAAATGAACACGATGCT
TTAATTCTAGAGAATTCATTAATCAAACAACTAAAACCAAAATATAATGTTTTATTAAGAGATGATAAAACTTATCCTTA
TATATATGTTGATTTAAATGAAGATTTCCCAAGACTAGAAATCACTAGAAAGATTGAAAAAGGTAAAAATATAAAATATT
TTGGTCCATATTCAAGTGGTGCAAAAGATATGCTTGATAGTATTTATGAAATTATACCTTTGGTTCAAAAAAAATCTTGT
ATAAAATCCAATAAAGCTTGTCTTTTTTTCCAAATTGGAAAATGTCTAGCTCCTTGTGAAGATAAAATTGATAAAAAAGA
TTATAAAAAATTACTTGATGATGCATTAACTTATATTTACAATAAATCAAAACTTATAAATAAACTAAAAGAGAAAATGG
AGTTTTATTCAAATAATTTTAGATTTGAAGAAGCTTTAAATATACGAGATAGAATAAAAACTATTGAGAAATCTCAAATA
AAAACAGCAATAGATTTAACAACAAATGATGATTTAGATATTTTTGCTATAAAATTTAGTTCAAGAAAAGCTGTATTAGT
AAAAATGTTCATAAGAGATGGAAAACTTGCATCATCGAGTTATGATTTTATAAAAATGAGTTCAGATTTGGAGTTTGATT
TAGAAGAAGCTTATAAAAGATCAATTATAAACTACTATTCAAATGAACTTCCTATTGTTCCAAAAGAGATTTTATTGGCA
GATGAAATTTTAGAACTTGAAGATATAGAAGATTTTTTACAAAAAAAATTTAATAAAAAAATTAAAATTATAAATCCTAA
AATAGATAAAAAAGCATCTATTATAAAAATTGCTTTAAATAATTGTGATGAACTATTAAGACTTGAAAATTTAAAAGATG
AAAATAGTATTTATCGTGATATAAAAGAGCTTTTCTCTTTAAGTGTTGAACCAAATTATATTGAAGTATTTGACAATTCA
CATTTTATGGGTCAAGCAAGAGTTGGTGGAATGATTGTTTGGGATAAAGAGCTTGAGAGTTTTAATAAAAAAGAGTATAG
AAATTATAATCTTGAAAGCCTTGATGAATATTCACAAATGAAAGAGGTTTTATATAGAAGAGTTGAAAGTTTTTCAAAAA
GCAGTCCTCCTGATTTATGGATAATTGATGGTGGATCAACTTTATTAAAACTTGCTTTTGAAATAGTTTCTTCTATTGGG
GTAAATTTAGATATTATTGCAATTTCTAAGCAAAAGGTTGATGCAAAAGCATATAGGGCTAAAGGAAATGCAAAAGATAT
TGTTCATTTTAAGCAAAACAAAGAGATAAAAAGCTTGGCTCTTCTTACTAGTGATAAAAGATTACAATTTATTCAAAGAT
TGAGAGATGAAGCACATAGATTTGCTATAAGTTTTCATAAAAAACAGAAAAGAAAAGAAGATAAAGAGATTTCACTTTTA
CAAATAAAAGGTATTGGTGAAGCAAAAATCAAAAAGCTTTTACTCTATTTTGGAGAGTTTCAAAAAATTAGAGATGCAAG
TTTTGAAGATTTAAAATCAGTGTTAAATGAAAAAGATGCAGAAAATTTAATTGAATATTTTACAAAGGAAAAAAGTGGCG
AAGATTCTACTAGATAA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(204-237)

GIY-YIG catalytic domain (GIY-YIG)

(14-96)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(382-543)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C0B442

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

51.92

96.926

0.503

Multiple sequence alignment