Detailed information    

insolico Bioinformatically predicted

Overview

Name   luxO   Type   Regulator
Locus tag   EPB57_RS23090 Genome accession   NZ_CP035700
Coordinates   3132492..3133898 (+) Length   468 a.a.
NCBI ID   WP_005380768.1    Uniprot ID   A0AAW9BFV3
Organism   Vibrio alginolyticus strain 2013V-1302     
Function   promote HapR production (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 3076780..3132200 3132492..3133898 flank 292


Gene organization within MGE regions


Location: 3076780..3133898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EPB57_RS22785 - 3076780..3077523 (-) 744 WP_065274723.1 SDR family oxidoreductase -
  EPB57_RS22790 - 3077658..3078161 (-) 504 WP_033907342.1 VC2046/SO_2500 family protein -
  EPB57_RS22795 sodB 3078316..3078900 (-) 585 WP_005396533.1 superoxide dismutase [Fe] -
  EPB57_RS22800 - 3079186..3079521 (+) 336 WP_017635833.1 Grx4 family monothiol glutaredoxin -
  EPB57_RS22805 - 3079757..3080779 (-) 1023 WP_154205126.1 tyrosine-type recombinase/integrase -
  EPB57_RS22810 - 3081013..3082275 (-) 1263 WP_154205127.1 LlaJI family restriction endonuclease -
  EPB57_RS22815 - 3082285..3083715 (-) 1431 WP_154205128.1 AAA family ATPase -
  EPB57_RS22820 dcm 3083796..3085136 (+) 1341 WP_053304191.1 DNA (cytosine-5-)-methyltransferase -
  EPB57_RS22825 - 3085181..3086746 (-) 1566 WP_154205129.1 hypothetical protein -
  EPB57_RS22830 - 3086743..3087366 (-) 624 WP_154205130.1 helix-turn-helix domain-containing protein -
  EPB57_RS22835 - 3087459..3087671 (+) 213 WP_045607456.1 hypothetical protein -
  EPB57_RS22840 - 3087786..3088325 (+) 540 WP_154205131.1 phage regulatory CII family protein -
  EPB57_RS22845 - 3088354..3088554 (+) 201 WP_042765728.1 hypothetical protein -
  EPB57_RS22850 - 3088554..3088781 (+) 228 WP_154205132.1 hypothetical protein -
  EPB57_RS22855 - 3088778..3089014 (+) 237 WP_154205133.1 hypothetical protein -
  EPB57_RS22860 - 3089020..3090900 (+) 1881 WP_154205134.1 replication endonuclease -
  EPB57_RS22865 - 3091028..3091246 (+) 219 WP_025517538.1 hypothetical protein -
  EPB57_RS22870 - 3091241..3091492 (-) 252 WP_154205135.1 ogr/Delta-like zinc finger family protein -
  EPB57_RS22875 - 3091558..3092589 (-) 1032 WP_154205136.1 phage portal protein -
  EPB57_RS22880 - 3092586..3094373 (-) 1788 WP_154205137.1 terminase family protein -
  EPB57_RS22885 - 3094550..3095422 (+) 873 WP_154205138.1 GPO family capsid scaffolding protein -
  EPB57_RS22890 - 3095422..3096444 (+) 1023 WP_154205139.1 phage major capsid protein, P2 family -
  EPB57_RS22895 gpM 3096437..3097153 (+) 717 WP_154205140.1 phage terminase small subunit -
  EPB57_RS22900 - 3097262..3097726 (+) 465 WP_154205141.1 head completion/stabilization protein -
  EPB57_RS22905 - 3097723..3098211 (+) 489 WP_053808827.1 phage tail protein -
  EPB57_RS22910 - 3098204..3098863 (+) 660 WP_154205142.1 phage virion morphogenesis protein -
  EPB57_RS22915 - 3098866..3099996 (+) 1131 WP_154205143.1 DUF2586 domain-containing protein -
  EPB57_RS22920 - 3100000..3100452 (+) 453 WP_017821175.1 phage protein -
  EPB57_RS22925 - 3100473..3100679 (+) 207 WP_017635443.1 TraR/DksA C4-type zinc finger protein -
  EPB57_RS22930 - 3100684..3100893 (+) 210 WP_017635442.1 HP1 family phage holin -
  EPB57_RS22935 - 3100880..3101470 (+) 591 WP_154205144.1 lysozyme -
  EPB57_RS22940 - 3101445..3101786 (+) 342 WP_064368662.1 hypothetical protein -
  EPB57_RS22945 - 3101809..3101997 (+) 189 WP_017635439.1 hypothetical protein -
  EPB57_RS22950 - 3101990..3102271 (+) 282 WP_064368661.1 putative phage tail assembly chaperone -
  EPB57_RS22955 - 3102487..3104466 (+) 1980 WP_064368660.1 phage tail tape measure protein -
  EPB57_RS22960 - 3104456..3104797 (+) 342 WP_017821183.1 DUF2590 family protein -
  EPB57_RS22965 - 3104794..3105999 (+) 1206 WP_154205145.1 baseplate J/gp47 family protein -
  EPB57_RS22970 - 3105992..3106588 (+) 597 WP_042522470.1 phage tail protein -
  EPB57_RS22975 - 3106595..3108373 (+) 1779 WP_064368658.1 phage tail protein -
  EPB57_RS22980 - 3108377..3108778 (+) 402 WP_064368657.1 hypothetical protein -
  EPB57_RS22985 - 3108775..3109665 (+) 891 WP_064368656.1 hypothetical protein -
  EPB57_RS22990 - 3109659..3110132 (+) 474 WP_154205146.1 DNA-binding protein -
  EPB57_RS22995 - 3110129..3111769 (+) 1641 WP_154205147.1 hypothetical protein -
  EPB57_RS23000 - 3112012..3113448 (+) 1437 WP_154205148.1 hypothetical protein -
  EPB57_RS23005 - 3114360..3114989 (+) 630 WP_017821191.1 DsbA family protein -
  EPB57_RS23010 - 3115068..3116393 (-) 1326 WP_017821192.1 Na+/H+ antiporter family protein -
  EPB57_RS23015 rnt 3116422..3117066 (-) 645 WP_005384888.1 ribonuclease T -
  EPB57_RS23025 - 3117408..3118289 (+) 882 WP_005384887.1 OmpA family protein -
  EPB57_RS23030 - 3118410..3118844 (-) 435 WP_005384886.1 DUF2753 domain-containing protein -
  EPB57_RS23035 gloA 3118995..3119411 (-) 417 WP_005380739.1 lactoylglutathione lyase -
  EPB57_RS23040 nth 3119444..3120085 (-) 642 WP_005380743.1 endonuclease III -
  EPB57_RS23045 - 3120150..3120842 (-) 693 WP_005380745.1 electron transport complex subunit E -
  EPB57_RS23050 rsxG 3120842..3121474 (-) 633 WP_047103464.1 electron transport complex subunit RsxG -
  EPB57_RS23055 rsxD 3121482..3122528 (-) 1047 WP_033907336.1 electron transport complex subunit RsxD -
  EPB57_RS23060 rsxC 3122528..3125392 (-) 2865 WP_154205149.1 electron transport complex subunit RsxC -
  EPB57_RS23065 rsxB 3125401..3125997 (-) 597 WP_005380760.1 electron transport complex subunit RsxB -
  EPB57_RS23070 rsxA 3126001..3126579 (-) 579 WP_005380762.1 electron transport complex subunit RsxA -
  EPB57_RS23075 pflB 3126886..3129183 (-) 2298 WP_054576231.1 formate C-acetyltransferase -
  EPB57_RS23085 uvrB 3130170..3132200 (+) 2031 WP_017636056.1 excinuclease ABC subunit UvrB -
  EPB57_RS23090 luxO 3132492..3133898 (+) 1407 WP_005380768.1 quorum-sensing sigma-54 dependent transcriptional regulator LuxO Regulator

Sequence

Protein


Download         Length: 468 a.a.        Molecular weight: 52094.70 Da        Isoelectric Point: 6.2547

>NTDB_id=343940 EPB57_RS23090 WP_005380768.1 3132492..3133898(+) (luxO) [Vibrio alginolyticus strain 2013V-1302]
MQQKPEGPKSRYLLMVEDTASVAALYRSYLTPLGIDINIVGTGRDAIESLNHRIPDLILLDLRLPDMTGMDVLHAVKKSH
PDVPIIFMTAHGSIDTAVEAMRHGSQDFLIKPCEADRLRVTVNNAIRKATKLKNEADNPGNQSYQGFIGSSQTMQQVYRT
IDSAASSKASIFITGESGTGKEVCAEAIHAASKRGDKPFIAINCAAIPKDLIESELFGHVKGAFTGAANDRQGAAELADG
GTLFLDELCEMDLDLQTKLLRFIQTGTFQKVGSSKMKSVDVRFVCATNRDPWKEVQEGRFREDLYYRLYVIPLHLPPLRE
RGEDVIEIAYSLLGYMSHEEGKSFIRFAPDVIERFNSYEWPGNVRQLQNVLRNIVVLNNGKEITLDMLPPPLNQPLDRPS
SVAKLIEPKAMTASEIMPLWMTEKMAIEQAIEACDGNIPRAAGYLDVSPSTIYRKLQAWNGKEERQKV

Nucleotide


Download         Length: 1407 bp        

>NTDB_id=343940 EPB57_RS23090 WP_005380768.1 3132492..3133898(+) (luxO) [Vibrio alginolyticus strain 2013V-1302]
ATGCAACAAAAACCCGAAGGCCCAAAGTCTCGTTACCTTTTAATGGTCGAGGACACCGCATCTGTTGCGGCTCTGTACCG
CTCATACCTGACACCGCTTGGCATAGATATCAATATTGTCGGCACAGGTAGGGATGCCATTGAGAGCCTAAATCATCGAA
TTCCAGATCTTATTTTACTCGATCTCCGTCTGCCAGATATGACGGGGATGGACGTTTTACATGCCGTTAAAAAGAGTCAT
CCCGACGTACCTATAATTTTTATGACCGCTCACGGTTCTATCGATACCGCTGTCGAGGCCATGCGTCATGGCTCACAAGA
CTTTCTAATTAAACCGTGTGAAGCAGACCGTTTACGTGTCACGGTTAACAATGCCATTCGTAAAGCGACCAAGCTAAAAA
ATGAAGCCGATAATCCAGGCAATCAGAGCTATCAGGGGTTTATCGGCAGTAGCCAAACCATGCAGCAGGTTTACCGTACG
ATAGATTCAGCGGCGAGCAGTAAAGCGAGTATTTTTATCACAGGTGAAAGTGGTACTGGTAAAGAGGTATGTGCCGAGGC
TATTCACGCAGCAAGTAAACGTGGTGACAAACCTTTTATTGCAATTAACTGTGCTGCAATTCCAAAAGATTTGATTGAGA
GTGAACTGTTTGGTCACGTAAAAGGGGCCTTTACTGGCGCTGCGAATGATCGTCAAGGGGCAGCTGAGTTAGCGGATGGC
GGCACACTTTTTCTAGATGAGCTTTGTGAGATGGACTTGGATTTACAAACCAAGTTGCTACGATTTATTCAAACGGGCAC
ATTCCAAAAAGTGGGTTCCTCAAAAATGAAGAGCGTGGATGTGCGCTTTGTTTGTGCCACTAACCGTGATCCCTGGAAAG
AGGTACAAGAAGGTCGATTCCGTGAAGATTTGTACTATCGTTTGTATGTCATTCCTTTGCATTTACCGCCTTTACGCGAA
CGAGGCGAAGATGTTATTGAAATTGCATACTCACTGCTAGGTTACATGTCACACGAAGAAGGAAAAAGCTTCATACGTTT
TGCGCCTGATGTCATCGAGCGATTCAACAGCTATGAGTGGCCGGGTAACGTTCGTCAGTTACAAAACGTGCTACGCAATA
TCGTTGTTCTAAACAACGGTAAAGAGATTACGTTGGACATGTTACCGCCACCGTTGAATCAACCGCTTGACCGTCCGTCG
TCTGTGGCTAAATTAATTGAGCCGAAAGCGATGACCGCATCTGAGATTATGCCATTATGGATGACGGAAAAAATGGCAAT
CGAGCAAGCGATTGAAGCATGTGATGGCAATATTCCTCGAGCGGCGGGATACCTTGATGTCAGTCCGTCGACGATTTACC
GCAAGTTACAGGCATGGAACGGCAAGGAAGAGCGGCAAAAAGTATGA

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(148-313)

Response regulator receiver domain (Response_reg)

(14-122)

Bacterial regulatory protein, Fis family (HTH_8)

(419-459)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  luxO Vibrio cholerae strain A1552

86.414

95.94

0.829

Multiple sequence alignment