Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   GC226_RS14065 Genome accession   NZ_CP045209
Coordinates   2878251..2878907 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 4     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2873251..2883907
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GC226_RS14035 (GC226_14100) yecA 2874502..2875167 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  GC226_RS14055 (GC226_14120) pgsA 2875817..2876365 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  GC226_RS14060 (GC226_14125) uvrC 2876422..2878254 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  GC226_RS14065 (GC226_14130) letA 2878251..2878907 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  GC226_RS25245 - 2879049..2879120 (+) 72 Protein_2745 transcriptional regulator -
  GC226_RS14070 (GC226_14135) yecU 2879203..2879379 (+) 177 WP_000590347.1 protein YecU -
  GC226_RS14075 (GC226_14140) yecF 2879366..2879590 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  GC226_RS14080 (GC226_14145) sdiA 2879657..2880379 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  GC226_RS14085 (GC226_14150) tcyN 2880609..2881361 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  GC226_RS14090 (GC226_14155) tcyL 2881358..2882026 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  GC226_RS14095 (GC226_14160) dcyD 2882041..2883027 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=343934 GC226_RS14065 WP_000611335.1 2878251..2878907(-) (letA) [Escherichia coli strain 4]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=343934 GC226_RS14065 WP_000611335.1 2878251..2878907(-) (letA) [Escherichia coli strain 4]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment