Detailed information NTG0343481

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: EWG56_RS08415
• Genome accession: NZ_CP035671
• Coordinates: 1698491..1699378 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain VB31683
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1693491..1704378

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EWG56_RS08385 (EWG56_08385)	-	1694297..1695058 (+)	762	WP_000323451.1	alpha/beta hydrolase family protein	-
EWG56_RS08390 (EWG56_08390)	-	1695304..1695759 (+)	456	WP_000106184.1	MarR family transcriptional regulator	-
EWG56_RS15030 (EWG56_08395)	-	1695881..1695982 (+)	102	WP_000731972.1	SE2200 family small protein	-
EWG56_RS08400 (EWG56_08400)	-	1696042..1697391 (-)	1350	WP_000953732.1	alkaline phosphatase	-
EWG56_RS08405 (EWG56_08405)	-	1697589..1697789 (+)	201	WP_000604723.1	hypothetical protein	-
EWG56_RS08410 (EWG56_08410)	braR	1697815..1698480 (+)	666	WP_000697883.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
EWG56_RS08415 (EWG56_08415)	braS	1698491..1699378 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
EWG56_RS08420 (EWG56_08420)	-	1699486..1700241 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
EWG56_RS08425 (EWG56_08425)	-	1700238..1702238 (+)	2001	WP_000776746.1	ABC transporter permease	-
EWG56_RS08430 (EWG56_08430)	-	1702902..1703015 (+)	114	WP_072384844.1	hypothetical protein	-
EWG56_RS08440 (EWG56_08440)	-	1703397..1703657 (+)	261	WP_072434822.1	hypothetical protein	-
EWG56_RS08445 (EWG56_08445)	-	1703667..1704164 (+)	498	WP_001065267.1	glutathione peroxidase	-
EWG56_RS08450 (EWG56_08450)	-	1704272..1704360 (-)	89	Protein_1614	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=343481 EWG56_RS08415 WP_000143420.1 1698491..1699378(+) (braS) [Staphylococcus aureus strain VB31683]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=343481 EWG56_RS08415 WP_000143420.1 1698491..1699378(+) (braS) [Staphylococcus aureus strain VB31683]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATATGTAAAAGATAATGGTATCGGTATTAGTGAGGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGTCAAAGTAACTCAAGTGGGATTGGCTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993