Detailed information NTG0343315

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: EVU95_RS07390
• Genome accession: NZ_CP035643
• Coordinates: 1538030..1539076 (-)
• Length: 348 a.a.
• NCBI ID: WP_002486322.1
• Uniprot ID: -
• Organism: Staphylococcus epidermidis strain E73
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1533030..1544076

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EVU95_RS07360 (EVU95_07635)	-	1533414..1534655 (-)	1242	WP_002457094.1	aminopeptidase	-
EVU95_RS07365 (EVU95_07640)	-	1534657..1534872 (-)	216	WP_001830421.1	DUF1128 domain-containing protein	-
EVU95_RS07370 (EVU95_07645)	-	1535013..1535477 (+)	465	WP_001830437.1	low molecular weight protein-tyrosine-phosphatase	-
EVU95_RS07375 (EVU95_07650)	-	1535485..1535769 (+)	285	WP_001830401.1	YtxH domain-containing protein	-
EVU95_RS07380 (EVU95_07655)	-	1536176..1537354 (+)	1179	WP_001830411.1	YihY/virulence factor BrkB family protein	-
EVU95_RS07385 (EVU95_07660)	vraR	1537411..1538040 (-)	630	WP_001830439.1	two-component system response regulator VraR	Regulator
EVU95_RS07390 (EVU95_07665)	vraS	1538030..1539076 (-)	1047	WP_002486322.1	sensor histidine kinase	Regulator
EVU95_RS07395 (EVU95_07670)	liaF	1539073..1539774 (-)	702	WP_002457093.1	cell wall-active antibiotics response protein LiaF	-
EVU95_RS07400 (EVU95_07675)	-	1539789..1540175 (-)	387	WP_001830382.1	hypothetical protein	-
EVU95_RS07405 (EVU95_07680)	map	1540333..1541088 (-)	756	WP_002457092.1	type I methionyl aminopeptidase	-
EVU95_RS07410 (EVU95_07685)	-	1541262..1542248 (+)	987	WP_002457091.1	aromatic acid exporter family protein	-
EVU95_RS07415 (EVU95_07690)	-	1542399..1542935 (-)	537	WP_001830372.1	hypothetical protein	-

Sequence

Protein

• Length: 348 a.a.
• Molecular weight: 40039.46 Da
• Isoelectric Point: 5.8512

>NTDB_id=343315 EVU95_RS07390 WP_002486322.1 1538030..1539076(-) (vraS) [Staphylococcus epidermidis strain E73]
MNHYIRAIGSMLILVYSMLIAFLFIDKVFVSIIFFQGMFYTQIFGIPVFLFLNLLIVLLCIIVGSVLAYKINQQNDWIIS
QIERSIEGQTVGINDQNIELYTETIDIYHTLVPLNQELHRLRMKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESKLEPPLNQQIPILEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFEVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNQEDYLLLRIQDNGKGFNVDEKFEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEENSSGD

Nucleotide

• Length: 1047 bp

>NTDB_id=343315 EVU95_RS07390 WP_002486322.1 1538030..1539076(-) (vraS) [Staphylococcus epidermidis strain E73]
ATGAATCACTACATAAGAGCTATAGGCTCAATGCTTATATTAGTATATAGTATGCTTATTGCTTTTTTATTTATTGATAA
AGTGTTTGTAAGTATTATCTTTTTTCAGGGGATGTTTTATACACAAATATTTGGAATACCTGTTTTTCTATTTTTAAATT
TATTAATTGTTCTTTTATGTATTATAGTTGGATCTGTTTTAGCTTATAAAATTAATCAACAAAATGATTGGATTATTTCA
CAAATAGAAAGATCAATAGAAGGACAAACAGTAGGTATCAATGATCAAAATATCGAATTATATACAGAAACGATAGATAT
TTATCATACACTAGTTCCATTAAATCAAGAATTACATCGACTTAGAATGAAGACTCAAAATTTAACTAATGAAAACTACA
ATATTAATGATGTAAAAGTCAAAAAGATTATCGAAGATGAGCGACAACGACTTGCCAGGGAATTACATGATTCTGTTAGT
CAACAATTATTTGCTGCGAGCATGATGCTATCGGCGATAAAAGAGTCGAAATTAGAACCACCTTTAAATCAACAGATACC
AATTCTTGAAAAAATGGTTCAAGACTCACAACTTGAAATGAGAGCTTTGTTATTACATTTAAGACCGATAGGTTTAAAAG
ATAAGTCTTTAGGTGAAGGAATTAAAGATTTAGTCATCGATTTACAAAAGAAAGTACCAATGAAAGTTGTGCATGAAATT
CAAGATTTTGAAGTGCCAAAAGGCATTGAAGATCACTTGTTCAGAATTACACAAGAAGCTATTTCAAATACATTGAGACA
TTCAAATGGTACAAAAGTAACTGTGGAATTATTTAATCAAGAGGATTATCTTTTACTAAGAATTCAAGATAATGGAAAAG
GATTTAATGTAGATGAAAAATTTGAACAAAGTTATGGTTTGAAAAATATGCGAGAACGAGCGTTAGAAATTGGTGCGACG
TTTCATATTGTATCTTTACCTGATTCAGGTACACGAATTGAAGTTAAGGCACCATTGAATAAGGAGGAGAATTCAAGTGG
CGATTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	92.733	98.851	0.917