Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   EU512_RS12790 Genome accession   NZ_CP035541
Coordinates   2535905..2536579 (-) Length   224 a.a.
NCBI ID   WP_000866106.1    Uniprot ID   -
Organism   Staphylococcus haemolyticus strain PK-01     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2531055..2554589 2535905..2536579 within 0
IScluster/Tn 2530384..2537339 2535905..2536579 within 0


Gene organization within MGE regions


Location: 2530384..2554589
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EU512_RS12750 (EU512_12760) - 2530384..2531058 (+) 675 WP_016931271.1 IS6 family transposase -
  EU512_RS12755 (EU512_12765) - 2531115..2531558 (-) 444 Protein_2504 GNAT family N-acetyltransferase -
  EU512_RS12760 (EU512_12770) - 2531555..2532190 (-) 636 Protein_2505 aminoglycoside 6-adenylyltransferase -
  EU512_RS12765 (EU512_12775) - 2532331..2533005 (-) 675 WP_001105960.1 IS6 family transposase -
  EU512_RS12770 (EU512_12780) - 2533062..2533238 (-) 177 Protein_2507 undecaprenyl-diphosphate phosphatase -
  EU512_RS12775 (EU512_12785) - 2533252..2533989 (-) 738 WP_000369394.1 ABC transporter permease -
  EU512_RS12780 (EU512_12790) - 2533982..2534911 (-) 930 WP_000793446.1 ABC transporter ATP-binding protein -
  EU512_RS12785 (EU512_12795) - 2535027..2535908 (-) 882 Protein_2510 sensor histidine kinase -
  EU512_RS12790 (EU512_12800) braR 2535905..2536579 (-) 675 WP_000866106.1 response regulator transcription factor Regulator
  EU512_RS12795 (EU512_12805) - 2536665..2537339 (-) 675 WP_001105960.1 IS6 family transposase -
  EU512_RS12800 (EU512_12810) - 2537531..2537602 (-) 72 Protein_2513 IS6 family transposase -
  EU512_RS12805 (EU512_12815) - 2537634..2538506 (+) 873 WP_302643315.1 NAD(P)/FAD-dependent oxidoreductase -
  EU512_RS12810 (EU512_12820) merR 2538806..2539213 (+) 408 WP_002380758.1 Hg(II)-responsive transcriptional regulator MerR -
  EU512_RS12815 (EU512_12825) - 2539230..2539583 (+) 354 WP_000746201.1 TlpA disulfide reductase family protein -
  EU512_RS12820 (EU512_12830) - 2539580..2540259 (+) 680 Protein_2517 cytochrome c biogenesis CcdA family protein -
  EU512_RS12825 (EU512_12835) - 2540394..2540732 (+) 339 WP_000968575.1 hypothetical protein -
  EU512_RS12830 (EU512_12840) merA 2540790..2542433 (+) 1644 WP_012818079.1 mercury(II) reductase -
  EU512_RS12835 (EU512_12845) merB 2542515..2543165 (+) 651 WP_000790334.1 organomercurial lyase MerB -
  EU512_RS12845 (EU512_12855) - 2543360..2543659 (-) 300 Protein_2521 hypothetical protein -
  EU512_RS12850 (EU512_12860) - 2543719..2544393 (-) 675 WP_001105986.1 IS6-like element IS257 family transposase -
  EU512_RS12855 (EU512_12865) - 2544423..2545364 (-) 942 WP_138109735.1 protein rep -
  EU512_RS12865 (EU512_12875) mobV 2545641..2546903 (-) 1263 WP_000119405.1 MobV family relaxase -
  EU512_RS12870 (EU512_12880) bleO 2547410..2547814 (-) 405 WP_001242578.1 bleomycin binding protein -
  EU512_RS12875 (EU512_12885) aadD1 2548031..2548801 (-) 771 WP_001795128.1 aminoglycoside O-nucleotidyltransferase ANT(4')-Ia -
  EU512_RS12880 (EU512_12890) - 2549044..2549718 (-) 675 WP_001105986.1 IS6-like element IS257 family transposase -
  EU512_RS12885 (EU512_12895) - 2549802..2550020 (+) 219 WP_138109736.1 hypothetical protein -
  EU512_RS12890 (EU512_12900) - 2550177..2550278 (+) 102 WP_002497230.1 type I toxin-antitoxin system Fst family toxin -
  EU512_RS12895 (EU512_12905) - 2550413..2551279 (-) 867 WP_138109737.1 DNA adenine methylase -
  EU512_RS12900 (EU512_12910) - 2551295..2553007 (-) 1713 WP_138109738.1 ATP-dependent endonuclease -
  EU512_RS12905 (EU512_12915) - 2553297..2553530 (+) 234 Protein_2532 IS5/IS1182 family transposase -
  EU512_RS12910 (EU512_12920) - 2554131..2554589 (+) 459 WP_016931397.1 DUF1307 domain-containing protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25839.93 Da        Isoelectric Point: 4.9884

>NTDB_id=343099 EU512_RS12790 WP_000866106.1 2535905..2536579(-) (braR) [Staphylococcus haemolyticus strain PK-01]
MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAPELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSR
NDSMDQVMAMQMGADDFIEKPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMH
SLFQNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVGDV

Nucleotide


Download         Length: 675 bp        

>NTDB_id=343099 EU512_RS12790 WP_000866106.1 2535905..2536579(-) (braR) [Staphylococcus haemolyticus strain PK-01]
ATGAAAGTATTAATCGTAGAGGATGACTTAGTTATCGGGAAGATGCTTGCTGAAGAGCTCAAGAAGTGGCAGCTAGAACC
GATCTTAATAGAAGGTTTCAATCATGTAATGGATGCCTTCAACACGAATGCACCGGAACTTGTGTTACTCGATATTAATT
TACCTGCCTTCAATGGTTATCACTGGTGTCAGGAGATTCGTAAAGTTTCTACTGTACCGATTATATTTATTAGTTCGCGT
AACGACAGTATGGATCAAGTAATGGCGATGCAGATGGGTGCGGATGATTTCATTGAGAAGCCATTTAATATGACTGTTAC
AATTACTAAGATTCAAGCACTATTACGCCGCACGTATGATTTCACCACTCAAGTTAATAATTTAACAGTAGATGATTGCG
AGTTACTACTTGATGCAGCAAAGCTTAAATTTAATGAAGAAACCATAGACCTGACACACACTGAATTGCAAATCATGCAT
AGCTTATTCCAGAACAAGGGCAAATTCGTCAGTCGTAATGCGTTAATCGAAAAATGCTGGGAATCAGAACACTTCATTGA
TGACAATACGCTTGCTGTCAACATTACACGTTTACGCAAAAAGCTACAAAAACTAGGACTTACAGATTTTATCGAAACGA
AGAAAAATGTCGGATATCGTGTAGGTGACGTATGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)

Response regulator receiver domain (Response_reg)

(3-111)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

66.516

98.661

0.656

Multiple sequence alignment