Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   EU512_RS04820 Genome accession   NZ_CP035541
Coordinates   982443..983159 (-) Length   238 a.a.
NCBI ID   WP_011275301.1    Uniprot ID   Q4L7S3
Organism   Staphylococcus haemolyticus strain PK-01     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 977443..988159
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EU512_RS04800 (EU512_04805) - 977485..978729 (+) 1245 WP_016931062.1 ammonium transporter -
  EU512_RS04805 (EU512_04810) - 978829..979788 (+) 960 WP_016931061.1 LacI family DNA-binding transcriptional regulator -
  EU512_RS04810 (EU512_04815) - 979873..981357 (+) 1485 WP_016931060.1 sucrose-6-phosphate hydrolase -
  EU512_RS04815 (EU512_04820) - 981361..982326 (+) 966 WP_016931059.1 carbohydrate kinase -
  EU512_RS04820 (EU512_04825) agrA 982443..983159 (-) 717 WP_011275301.1 quorum-sensing response regulator AgrA Regulator
  EU512_RS04825 (EU512_04830) agrC 983178..984461 (-) 1284 WP_029376653.1 quorum-sensing sensor histidine kinase AgrC -
  EU512_RS04830 (EU512_04835) agrD 984493..984630 (-) 138 WP_011275303.1 cyclic lactone autoinducer peptide AgrD -
  EU512_RS04835 (EU512_04840) - 984633..985199 (-) 567 WP_011275304.1 accessory gene regulator AgrB -
  EU512_RS04840 (EU512_04845) - 985928..986713 (-) 786 WP_016931057.1 carbon-nitrogen family hydrolase -
  EU512_RS04845 (EU512_04850) - 986906..987529 (-) 624 WP_016931056.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27801.74 Da        Isoelectric Point: 5.2189

>NTDB_id=343075 EU512_RS04820 WP_011275301.1 982443..983159(-) (agrA) [Staphylococcus haemolyticus strain PK-01]
MKIFICEDDVKQRENMVSIINNYIMIEEKPMEIALATDDPYEVIEKSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPSQLQSRIIDCLETAHTRLKLLSKESTVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVVNRHNIESIDSKERIVNFKNGEHCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=343075 EU512_RS04820 WP_011275301.1 982443..983159(-) (agrA) [Staphylococcus haemolyticus strain PK-01]
ATGAAAATATTCATTTGTGAAGATGATGTAAAACAACGCGAAAATATGGTTTCAATTATTAATAATTACATTATGATTGA
AGAAAAACCTATGGAGATTGCGCTTGCAACAGACGATCCTTATGAAGTCATTGAAAAATCTAAAGAGATGAATGATGTCG
GATGTTACTTTCTAGATATTCAATTAGAGGCTGATATCAACGGTATTAAATTAGGTAGTGAAATTCGTAAGTATGACCCA
ATTGGGAATATCATATTCGTTACAAGTCATAGTGAGTTAACGTACCTAACCTTTGTTTACAAAGTGTCAGCGATGGATTT
TATCTTTAAAGATGATCCAAGCCAATTACAGTCCAGAATTATTGATTGCTTAGAAACTGCACATACCCGCTTAAAATTAT
TATCTAAAGAAAGTACTGTTGAGACGATTGAATTGAAACGAGGAAGTAATTCAATTTATGTTCAATATGATGACGTAATG
TTTTTCGAATCATCTACAAAATCACATCGGTTAATCGCACATTTAGATAATCGTCAAATTGAGTTCTATGGCAATTTAAA
AGAACTTGCACAACTTGATGAGCGGTTCTTTAGATGTCACAACAGCTTCGTTGTTAATAGACATAATATTGAATCCATAG
ATTCAAAAGAACGTATTGTCAATTTTAAAAACGGTGAGCACTGTTTTGCTTCCGTTCGTAATGTAAAAAAAATATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4L7S3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878

Multiple sequence alignment