Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FSA40_RS09835 Genome accession   NZ_CP044493
Coordinates   1936954..1938909 (-) Length   651 a.a.
NCBI ID   WP_002268465.1    Uniprot ID   -
Organism   Streptococcus mutans strain MD     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1931954..1943909
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FSA40_RS09810 (FSA40_1967) spx 1932457..1932855 (-) 399 WP_002262391.1 transcriptional regulator Spx -
  FSA40_RS09815 (FSA40_1968) recA 1932940..1934091 (-) 1152 WP_002262392.1 recombinase RecA Machinery gene
  FSA40_RS09820 (FSA40_1969) cinA 1934131..1935387 (-) 1257 WP_151416454.1 competence/damage-inducible protein A Machinery gene
  FSA40_RS09825 (FSA40_1970) - 1935536..1936096 (-) 561 WP_002268198.1 DNA-3-methyladenine glycosylase I -
  FSA40_RS09830 (FSA40_1971) ruvA 1936178..1936771 (-) 594 WP_002262395.1 Holliday junction branch migration protein RuvA Machinery gene
  FSA40_RS09835 (FSA40_1972) hexB 1936954..1938909 (-) 1956 WP_002268465.1 DNA mismatch repair endonuclease MutL Machinery gene
  FSA40_RS09840 - 1939134..1939412 (+) 279 Protein_1838 transposase -
  FSA40_RS09845 (FSA40_1973) hexA 1939407..1941956 (-) 2550 WP_002262398.1 DNA mismatch repair protein MutS Machinery gene
  FSA40_RS09850 (FSA40_1974) - 1941949..1942296 (-) 348 WP_002273523.1 YlbF family regulator -
  FSA40_RS09855 (FSA40_1975) argR 1942293..1942730 (-) 438 WP_151416455.1 arginine repressor -
  FSA40_RS09860 (FSA40_1976) - 1943227..1943667 (-) 441 WP_253667314.1 Crp/Fnr family transcriptional regulator -

Sequence

Protein


Download         Length: 651 a.a.        Molecular weight: 73756.44 Da        Isoelectric Point: 6.4076

>NTDB_id=342968 FSA40_RS09835 WP_002268465.1 1936954..1938909(-) (hexB) [Streptococcus mutans strain MD]
MSKIVELPEVLANQIAAGEVIERPASVVKELVENAIDADSSQITIEIEESGLKKIQVIDNGQGIEQADVIMSLRRHATSK
IKKQSDLFRIRTLGFRGEALPSIASISRLTLKTATKGEIHGTLVIANGGKIEKEEAISTPIGTKVSVENLFFNTPARLKY
MKSLQAELAHIIDVINRLSLAHPEIAFTLINDGRELTKTSGKGDLRQALAGIYGVTTAKKMVEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMNLISS
AIADSLREQELIPDALENLAKTSTNKKQKFEQTQLPLKQSNLYYDKTQNDFFLKETTVSEASSEFTVVDKAVNITDNVSG
HSSVKYAQRQMRTCENKEHPSLAMTDKQQKRQLSRIVESLENEEKSTFPELEYFGQMHGTYLFAQGEGGLYIIDQHAAQE
RVKYEYYRDKIGEVDNSLQQLLVPYLFEFPANDFMTLQEKMSILNEVGIHLENYGENTFILREHPIWLQEKEIESAVYEM
CDMLLLTNEVSIKKYRAELAIMMSCKRSIKANHTLDDYSARNLLIQLSQCKNPYNCPHGRPVLVNFTKADMEKMFRRIQE
NHTSLRELGKY

Nucleotide


Download         Length: 1956 bp        

>NTDB_id=342968 FSA40_RS09835 WP_002268465.1 1936954..1938909(-) (hexB) [Streptococcus mutans strain MD]
ATGTCAAAAATTGTTGAACTGCCAGAAGTTTTAGCCAATCAAATTGCTGCTGGAGAGGTTATTGAAAGACCAGCTAGTGT
CGTAAAAGAACTAGTTGAGAATGCTATTGACGCTGATAGCAGCCAAATTACAATAGAAATTGAAGAATCAGGACTGAAAA
AAATTCAAGTGATTGATAATGGTCAAGGAATAGAACAAGCGGATGTAATTATGAGCTTACGTCGCCATGCAACTAGTAAG
ATTAAAAAACAATCCGATCTTTTTAGAATTAGGACCTTAGGTTTTAGAGGTGAGGCCCTTCCATCAATTGCTTCTATTAG
CAGACTAACATTAAAAACAGCAACAAAAGGGGAAATACATGGCACTTTAGTAATCGCAAATGGAGGTAAAATTGAAAAAG
AAGAAGCCATTAGTACCCCTATTGGAACCAAAGTGAGTGTTGAAAATCTTTTCTTCAATACCCCTGCTCGCCTTAAATAT
ATGAAAAGTTTGCAGGCAGAGCTTGCTCATATTATTGATGTTATTAACCGTCTTAGCTTGGCGCATCCCGAAATTGCTTT
CACGCTTATTAATGATGGCCGTGAATTAACAAAGACGTCAGGTAAAGGCGATCTGCGTCAAGCTTTAGCGGGTATTTATG
GGGTAACCACTGCTAAAAAAATGGTCGAAATTTCAAATGCAGATCTTGATTTTGAGGTATCTGGTTATATTAGTTTGCCT
GAATTAACCCGAGCTAATCGCAATTATATTACCATTCTTATTAATGGGCGTTATATCAAAAATTTTTTGCTCAATCGTGC
TATTCTTGATGGTTATGGTTCAAAATTAATGGTGGGACGTTTTCCAATTGCTGTTATTGATATTCAGATTGACCCTTATT
TAGCAGATGTTAATGTTCATCCAACTAAGCAGGAAGTTCGCATTTCTAAAGAAAAAGAGTTAATGAATCTCATTAGTTCG
GCAATTGCAGATAGTTTAAGAGAACAAGAGTTAATTCCTGATGCTTTGGAAAATCTTGCTAAAACTAGCACAAACAAGAA
ACAAAAGTTTGAACAAACACAGCTTCCTCTTAAACAATCAAATCTTTACTATGATAAGACTCAAAATGACTTCTTTCTCA
AAGAAACGACAGTTTCAGAAGCATCAAGCGAGTTTACAGTAGTTGATAAAGCTGTAAATATTACTGATAATGTATCAGGA
CATAGCAGTGTAAAATATGCTCAACGTCAAATGAGAACTTGTGAAAACAAAGAGCATCCAAGTCTTGCTATGACAGATAA
GCAACAAAAGCGACAGCTTAGTAGAATTGTTGAAAGTCTAGAAAATGAAGAAAAGTCAACTTTTCCTGAGTTAGAATATT
TTGGTCAAATGCATGGAACTTACCTCTTTGCTCAAGGTGAAGGGGGGCTTTATATTATAGATCAACATGCTGCTCAAGAA
CGTGTTAAATATGAATATTATCGTGATAAAATTGGAGAAGTAGACAATAGTTTACAGCAGCTTTTAGTACCTTATCTTTT
TGAATTTCCTGCTAATGATTTTATGACCTTACAAGAAAAAATGAGCATTTTAAATGAGGTGGGAATTCACTTAGAAAACT
ATGGAGAGAATACTTTTATTTTGAGGGAACATCCTATTTGGTTACAGGAAAAAGAAATTGAATCAGCCGTTTATGAGATG
TGTGACATGTTGCTGTTGACAAATGAAGTCTCCATTAAGAAATATCGAGCGGAATTAGCTATTATGATGTCTTGCAAGCG
TTCTATCAAGGCTAATCATACTTTGGATGATTATTCTGCCAGAAATCTCTTAATTCAATTATCACAGTGCAAAAATCCTT
ACAATTGTCCTCATGGACGTCCTGTGCTTGTGAATTTCACAAAAGCTGATATGGAAAAGATGTTTCGTCGCATTCAGGAA
AACCATACTAGTTTGAGAGAATTAGGGAAATACTGA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(453-595)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-135)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.605

100

0.704

Multiple sequence alignment