Detailed information NTG0342857

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FSA31_RS09540
• Genome accession: NZ_CP044492
• Coordinates: 1897655..1900204 (-)
• Length: 849 a.a.
• NCBI ID: WP_002268464.1
• Uniprot ID: -
• Organism: Streptococcus mutans strain T8
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1892655..1905204

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FSA31_RS09520 (FSA31_1876)	-	1893784..1894344 (-)	561	WP_002284635.1	DNA-3-methyladenine glycosylase I	-
FSA31_RS09525 (FSA31_1877)	ruvA	1894426..1895019 (-)	594	WP_002262395.1	Holliday junction branch migration protein RuvA	Machinery gene
FSA31_RS09530 (FSA31_1878)	hexB	1895202..1897157 (-)	1956	WP_002268465.1	DNA mismatch repair endonuclease MutL	Machinery gene
FSA31_RS09535	-	1897382..1897660 (+)	279	Protein_1780	transposase	-
FSA31_RS09540 (FSA31_1879)	hexA	1897655..1900204 (-)	2550	WP_002268464.1	DNA mismatch repair protein MutS	Machinery gene
FSA31_RS09545 (FSA31_1880)	-	1900197..1900544 (-)	348	WP_002268194.1	YlbF family regulator	-
FSA31_RS09550 (FSA31_1881)	argR	1900541..1900978 (-)	438	WP_002268193.1	arginine repressor	-
FSA31_RS09555 (FSA31_1882)	-	1901375..1901899 (-)	525	WP_002284636.1	Crp/Fnr family transcriptional regulator	-
FSA31_RS09990 (FSA31_1884)	-	1902276..1902500 (-)	225	WP_002266969.1	hypothetical protein	-
FSA31_RS09565	-	1902805..1903275 (+)	471	Protein_1786	arginine repressor	-
FSA31_RS09570 (FSA31_1886)	argS	1903376..1905067 (+)	1692	WP_002284637.1	arginine--tRNA ligase	-

Sequence

Protein

• Length: 849 a.a.
• Molecular weight: 95341.59 Da
• Isoelectric Point: 4.9162

>NTDB_id=342857 FSA31_RS09540 WP_002268464.1 1897655..1900204(-) (hexA) [Streptococcus mutans strain T8]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAIKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLI
DLGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSTKPDSANNFLVSLDTDGSQFGLSYMDLSTGEFYATTLADLPA
VRSEVLNLKARELVIGFELSENEEQLFRKQMNLLLSFEKTVYDDVHLLDDQLKAIELAAAGKLLQYVHNTQKRELSHLQK
LVHYEIKDYLQMAYATKSSLDLLENARSGKKHGSLYWLLDETKTAMGTRLLRTWIDRPLVSSSLISERQDIIQTFLDHFF
ERSDLSDSLKGVYDIERLASRVSFGKANPKDLLQLGQTLSQVPVIKTILESFASSSLESLINQIDTLPELEALIRSAIDS
NAPITITEGGMIREGFDETLDKYRTVMREGTSWIADIETKERQKSGISTLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTSELAKIEGEMLEAREESANLEYDIFMRIRSQVESYIERLQNLAKSLATVDVLQSLAVVAENNHYVRPSFN
HQQEISIENGRHAVVEKVMGSQEYIPNTINFDQKTSIQLITGPNMSGKSTYMRQLALTVIMAQLGSFVAADSADLPIFDA
IFTRIGAADDLISGQSTFMVEMMEANHAIKAATPNSLILFDELGRGTATYDGMALAQAIIEYIHNKVGAKTLFATHYHEL
TDLSTRLTSLVNVHVATLEKDGEVTFLHKIADGPADKSYGIHVAKIAGLPKDLLNRADHILVDLEKMSAAVSVNLKNETK
ESQPVEEQLSLFAIDNNYEELIKKLKQLDLTNLTPRESMNALFDLKELL

Nucleotide

• Length: 2550 bp

>NTDB_id=342857 FSA31_RS09540 WP_002268464.1 1897655..1900204(-) (hexA) [Streptococcus mutans strain T8]
ATGACTAAGGAAAAACTCTCTCCAGGAATGCAGCAGTATTTGGATATCAAAAAAGACTATCCAGATGCTTTTTTGCTTTT
CCGCATGGGAGATTTTTATGAACTATTTTATGATGATGCTATCAAGGCTGCTCAAATTTTAGAAATTAGCTTAACAAGTC
GTAATAAAAATGCTGACAATCCTATTCCGATGGCTGGTGTCCCTTATCATTCAGCTCAACAATATATTGATGTTTTGATT
GATTTGGGTTATAAGGTTGCCATTGCTGAGCAGATGGAAGACCCTAAAAAAGCTGTTGGCGTTGTCAAACGTGAAGTGGT
TCAAGTGATTACCCCGGGTACTGTTGTTGATTCAACTAAGCCAGACAGTGCTAATAATTTTTTAGTCTCTCTGGATACTG
ATGGCAGTCAGTTTGGCCTTTCTTACATGGATTTATCTACTGGGGAATTTTATGCGACAACATTAGCAGATTTGCCAGCA
GTGAGAAGCGAAGTCCTCAATCTCAAGGCGCGTGAATTAGTTATTGGTTTTGAACTGAGTGAGAATGAAGAACAGCTTTT
TCGTAAGCAGATGAACCTGCTCTTATCTTTTGAAAAAACTGTCTATGACGATGTACATTTATTGGATGATCAATTAAAAG
CAATAGAACTTGCTGCAGCTGGCAAACTCTTGCAATATGTTCATAACACACAAAAACGTGAGTTGAGTCATTTGCAAAAG
TTGGTGCATTATGAAATTAAAGATTACTTGCAGATGGCTTATGCTACAAAATCTAGCTTGGATCTGTTAGAAAATGCCAG
AAGCGGGAAAAAACATGGCAGTCTCTACTGGCTTTTAGATGAGACAAAAACAGCTATGGGGACACGCCTTTTGCGAACTT
GGATTGATCGTCCTTTGGTCAGTTCAAGCCTTATCAGTGAACGTCAAGATATTATTCAGACTTTTCTAGATCACTTTTTT
GAGCGCAGTGATCTTAGTGACAGCTTAAAAGGTGTTTATGATATTGAACGTTTGGCCAGCCGTGTTTCATTTGGGAAGGC
CAATCCTAAGGATTTATTGCAATTGGGTCAGACCTTAAGTCAAGTTCCTGTCATTAAGACTATTCTTGAAAGTTTTGCCA
GTTCTAGTTTGGAAAGCCTAATTAATCAAATTGATACTCTTCCAGAATTGGAAGCATTGATTCGTTCGGCTATTGACTCT
AATGCACCTATAACTATTACAGAAGGCGGTATGATTCGAGAGGGGTTTGATGAAACTTTAGATAAGTATCGAACGGTAAT
GCGCGAAGGGACGAGTTGGATTGCTGACATTGAGACTAAGGAACGTCAGAAAAGCGGCATCTCAACCTTGAAGATTGATT
ATAACAAAAAAGACGGTTATTATTTCCATGTCACCAACTCTAATTTGTCTTTAGTACCAGATTACTTCTTTAGAAAGGCA
ACGCTTAAAAATTCTGAGCGCTTTGGGACATCAGAGCTTGCAAAAATTGAAGGTGAAATGTTAGAAGCGCGTGAAGAATC
AGCCAATTTAGAATATGATATTTTCATGCGTATCAGATCACAGGTTGAATCTTATATTGAGCGTCTTCAAAATCTGGCCA
AGAGTCTAGCAACTGTTGATGTTTTGCAAAGTTTAGCAGTAGTAGCTGAGAATAATCATTATGTCAGACCTTCTTTTAAT
CATCAGCAGGAAATCAGTATTGAAAATGGTCGCCATGCTGTTGTTGAGAAGGTTATGGGAAGCCAAGAATATATTCCCAA
TACTATCAATTTTGACCAAAAGACTAGTATTCAACTGATTACTGGACCTAATATGAGCGGTAAGTCAACTTACATGCGGC
AATTAGCTCTGACAGTTATTATGGCTCAATTAGGTTCTTTTGTAGCAGCTGATTCAGCTGATTTGCCGATTTTTGATGCT
ATTTTTACACGTATTGGTGCTGCAGATGATTTAATTTCAGGGCAGTCTACCTTTATGGTAGAGATGATGGAAGCCAATCA
TGCTATCAAGGCAGCGACACCTAATTCACTCATTTTATTTGATGAATTAGGACGTGGTACAGCAACTTATGATGGTATGG
CTTTAGCACAGGCTATTATTGAGTATATTCATAATAAAGTTGGGGCTAAAACGCTATTTGCTACCCATTATCATGAGTTG
ACAGACTTGTCAACTAGATTGACAAGTCTTGTCAATGTACATGTTGCTACTCTTGAAAAAGATGGAGAGGTCACTTTTCT
TCATAAAATTGCTGATGGACCAGCTGATAAATCTTATGGAATCCATGTTGCTAAAATTGCCGGCTTGCCTAAAGATTTAC
TTAATCGAGCTGATCACATATTAGTTGATTTAGAAAAAATGAGTGCAGCTGTCTCAGTCAATCTTAAAAACGAGACCAAA
GAAAGCCAACCTGTGGAAGAGCAGTTGTCACTTTTTGCTATTGATAATAATTATGAAGAATTAATCAAAAAATTGAAACA
GTTGGACCTTACCAATTTAACACCAAGAGAATCCATGAATGCCTTATTTGATTTGAAGGAACTATTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

• MutS family domain IV (MutS_IV) (415-506)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.268	100	0.724
mutS	Pseudomonas stutzeri strain ATCC 17587	37.34	100	0.377