Detailed information NTG0342482

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: ETT45_RS08255
• Genome accession: NZ_CP035454
• Coordinates: 1629313..1631757 (-)
• Length: 814 a.a.
• NCBI ID: WP_136129607.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm54
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1624313..1636757

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT45_RS08230 (ETT45_08225)	-	1624439..1625938 (+)	1500	WP_002991665.1	C69 family dipeptidase	-
ETT45_RS09045	-	1626262..1626614 (+)	353	Protein_1523	NUDIX domain-containing protein	-
ETT45_RS08240 (ETT45_08235)	-	1626600..1626927 (-)	328	Protein_1524	helix-turn-helix domain-containing protein	-
ETT45_RS08245 (ETT45_08240)	groL	1627178..1628809 (-)	1632	WP_002982320.1	chaperonin GroEL	-
ETT45_RS08250 (ETT45_08245)	groES	1628845..1629135 (-)	291	WP_002991292.1	co-chaperone GroES	-
ETT45_RS08255 (ETT45_08250)	clpC	1629313..1631757 (-)	2445	WP_136129607.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
ETT45_RS08260 (ETT45_08255)	-	1631757..1632218 (-)	462	WP_002982312.1	CtsR family transcriptional regulator	-
ETT45_RS08265 (ETT45_08260)	-	1632414..1632617 (-)	204	WP_002991299.1	cold-shock protein	-
ETT45_RS08275 (ETT45_08270)	ahpC	1633611..1634171 (+)	561	WP_002982304.1	alkyl hydroperoxide reductase subunit C	-
ETT45_RS08280 (ETT45_08275)	ahpF	1634192..1635724 (+)	1533	WP_030126835.1	alkyl hydroperoxide reductase subunit F	-

Sequence

Protein

• Length: 814 a.a.
• Molecular weight: 90684.38 Da
• Isoelectric Point: 6.8610

>NTDB_id=342482 ETT45_RS08255 WP_136129607.1 1629313..1631757(-) (clpC) [Streptococcus pyogenes strain emm54]
MIMYSTKMQDIFRQAQFQAARFDSHCLETWHVLLAMVAVDNSLANMILSEYDAQVAIEEYEAAAILAMGKTPKEQLSRVD
FRPQSKTLTNLLAFAQAISQITRDQEVGSEHVLFAILLNPDIMASRLLEIAGYQIKDNGNGQPRLADLRKAIERHAGYSK
EMIKAIHELRKPKKTKTQGTFSDMMKPPSTAGELSDFTRDLTEMARQGLLESVIGRDQEVSRMIQVLSRKTKNNPVLVGD
AGVGKTALAYGLAQRIANGAIPYELKEMRVLELDMMSVVAGTRFRGDFEERMNQIIDDIEADGQIILFVDELHTIMGSGS
GIDSTLDAANILKPALSRGTLHMVGATTQEEYQKHIEKDAALSRRFAKILIEEPNTEDAYQILMGLKLSYETYHNVSISN
EAVKTAVKMAHRYLTSKNLPDSAIDLLDEASAAVQNMVKKSAPETLTPIDQALINGDMKKVSRLLAKEAKGQMRKPTPVT
EDDILATLSKLSGIPLEKLTQADSKKYLNLEKELHKRVIGQDAAVTAISRAIRRNQSGIRTGKRPIGSFMFLGPTGVGKT
ELAKALAEVLFDDEAALIRFDMSEYMEKFAASRLNGAPPGYVGYDEGGELTQKVRNKPYSVLLFDEVEKAHPDIFNVLLQ
VLDDGILADSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGVKDIHQDHQAMEKRILEELRKTYRPEFINRIDEKVVFH
SLTQDNMRDVVKIMVQPLITTLAEKGITLKIQPLALKHLSEVGYDEHMGARPLRRTLQTEIEDKLSELILSRELTSGHTL
KIGLSHGKLTFHIA

Nucleotide

• Length: 2445 bp

>NTDB_id=342482 ETT45_RS08255 WP_136129607.1 1629313..1631757(-) (clpC) [Streptococcus pyogenes strain emm54]
ATGATTATGTATTCAACGAAGATGCAAGACATTTTTAGACAGGCGCAGTTCCAAGCTGCTCGCTTTGATAGCCATTGCCT
GGAAACTTGGCATGTTTTGTTAGCTATGGTAGCTGTAGATAATTCTTTAGCAAATATGATTTTAAGTGAATATGATGCCC
AAGTCGCCATAGAAGAATATGAAGCTGCAGCTATTTTAGCCATGGGCAAAACCCCTAAGGAACAGTTGTCTCGTGTAGAC
TTCAGACCTCAATCTAAAACTTTGACTAACTTGTTAGCTTTTGCGCAGGCTATTAGCCAAATCACTAGGGATCAAGAAGT
CGGCTCTGAGCATGTCTTATTTGCTATTTTATTGAATCCAGATATCATGGCGAGTCGTTTGTTAGAAATAGCTGGCTATC
AGATAAAAGATAACGGCAATGGGCAGCCGCGATTAGCTGACTTGCGAAAAGCAATAGAACGTCATGCAGGTTACAGTAAG
GAAATGATCAAGGCTATTCACGAACTACGTAAGCCTAAAAAAACGAAAACACAAGGGACCTTTTCAGATATGATGAAGCC
ACCAAGTACAGCTGGTGAGTTGAGTGATTTCACAAGAGATTTGACTGAAATGGCAAGACAAGGTTTGTTAGAATCGGTGA
TTGGACGTGACCAAGAAGTATCTCGTATGATTCAGGTACTAAGTCGTAAAACGAAAAACAATCCTGTCTTGGTAGGTGAT
GCAGGTGTTGGTAAAACTGCGCTTGCTTATGGCCTTGCTCAACGGATTGCAAATGGCGCTATTCCTTATGAACTTAAGGA
GATGCGTGTCCTAGAATTAGACATGATGAGTGTGGTAGCAGGAACCCGTTTTCGTGGGGATTTTGAAGAGCGCATGAATC
AAATCATTGATGATATTGAAGCTGATGGTCAGATTATTCTTTTTGTTGATGAACTACATACTATTATGGGTTCTGGCAGT
GGTATTGACAGTACACTTGATGCGGCTAACATTTTAAAACCAGCATTATCGCGCGGTACTCTTCATATGGTTGGAGCAAC
AACTCAAGAAGAATATCAAAAACATATTGAAAAAGATGCAGCTCTTTCGCGTCGTTTTGCTAAAATATTAATTGAAGAAC
CTAATACAGAAGATGCTTATCAGATTTTGATGGGCCTAAAATTATCTTATGAGACCTACCATAATGTCTCGATATCAAAT
GAGGCAGTTAAAACAGCTGTAAAAATGGCACACCGTTATTTAACCAGTAAAAATCTCCCTGATTCAGCTATCGATTTATT
AGATGAAGCTAGTGCTGCTGTGCAAAACATGGTGAAAAAATCAGCTCCTGAGACTTTAACACCAATAGACCAAGCTCTTA
TCAATGGTGATATGAAAAAAGTATCTCGCCTCTTAGCTAAAGAAGCAAAAGGTCAGATGAGAAAACCAACACCAGTGACA
GAAGATGATATTTTGGCAACCTTGAGTAAGTTATCGGGAATTCCACTTGAAAAACTGACGCAAGCTGATAGTAAAAAATA
CCTCAATTTAGAAAAAGAACTGCATAAGCGTGTGATTGGTCAGGATGCTGCTGTTACGGCTATTTCAAGAGCCATTCGTC
GCAATCAGTCAGGTATTCGAACAGGAAAACGTCCTATTGGATCATTTATGTTTCTTGGCCCAACAGGAGTAGGTAAGACA
GAACTAGCAAAGGCCCTTGCAGAAGTTCTCTTTGATGATGAAGCAGCGCTTATTCGTTTTGATATGTCTGAGTACATGGA
AAAATTCGCAGCGTCTAGGCTTAATGGAGCACCTCCTGGTTATGTCGGCTATGATGAAGGAGGTGAACTGACACAGAAAG
TTAGAAATAAACCTTATTCAGTCTTGCTTTTTGATGAAGTGGAAAAAGCACATCCTGATATTTTTAACGTTCTCCTTCAA
GTATTAGATGATGGTATATTGGCTGATAGTCGTGGGCGTAAGGTCGATTTTTCAAATACTATTATTATCATGACCAGCAA
TCTTGGCGCAACAGCCCTGCGCGATGATAAAACGGTCGGTTTTGGGGTCAAAGACATTCACCAAGACCATCAAGCTATGG
AGAAACGTATTTTAGAAGAATTAAGAAAAACTTACCGCCCAGAATTTATCAATCGTATTGATGAAAAAGTGGTCTTTCAT
AGTCTGACCCAAGATAACATGCGCGATGTGGTTAAAATCATGGTACAGCCCCTGATTACTACATTGGCAGAAAAAGGTAT
TACCCTTAAAATTCAGCCTTTGGCCTTGAAACATTTGTCCGAGGTCGGCTATGATGAGCATATGGGGGCAAGACCATTAC
GTCGAACGCTGCAAACTGAGATAGAAGATAAGCTATCAGAGCTTATCCTTTCTCGAGAATTGACAAGTGGGCATACGCTA
AAAATTGGATTATCACATGGCAAATTAACGTTTCACATAGCTTAA

Domains

Predicted by InterproScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (236-368)

• AAA domain (Cdc48 subfamily) (AAA_2) (544-715)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (722-801)

• AAA lid domain (AAA_lid_9) (376-459)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-130)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus mutans UA159	75.031	99.877	0.749
clpC	Streptococcus thermophilus LMG 18311	71.201	100	0.714
clpC	Streptococcus thermophilus LMD-9	71.078	100	0.713
clpC	Streptococcus pneumoniae TIGR4	65.971	100	0.66
clpC	Streptococcus pneumoniae Rx1	65.971	100	0.66
clpC	Streptococcus pneumoniae D39	65.971	100	0.66
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.733	100	0.491
clpC	Bacillus subtilis subsp. subtilis str. 168	42.326	100	0.434