Detailed information NTG0342408

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: ETT46_RS03945
• Genome accession: NZ_CP035453
• Coordinates: 745851..747080 (+)
• Length: 409 a.a.
• NCBI ID: WP_136264886.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm100
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 740851..752080

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT46_RS03920 (ETT46_03915)	-	741467..742744 (-)	1278	WP_010922170.1	hydroxymethylglutaryl-CoA reductase, degradative	-
ETT46_RS03925 (ETT46_03920)	-	742731..743906 (-)	1176	WP_002993959.1	hydroxymethylglutaryl-CoA synthase	-
ETT46_RS03930 (ETT46_03925)	-	744115..744954 (+)	840	WP_010922172.1	thymidylate synthase	-
ETT46_RS03935 (ETT46_03930)	-	745034..745531 (+)	498	WP_002984955.1	dihydrofolate reductase	-
ETT46_RS03940 (ETT46_03935)	-	745551..745721 (+)	171	WP_002984950.1	hypothetical protein	-
ETT46_RS03945 (ETT46_03940)	clpX	745851..747080 (+)	1230	WP_136264886.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
ETT46_RS03950 (ETT46_03945)	yihA	747090..747689 (+)	600	WP_002984945.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
ETT46_RS03955 (ETT46_03950)	-	747837..748580 (+)	744	WP_002984942.1	hypothetical protein	-
ETT46_RS03960 (ETT46_03955)	-	748638..750737 (-)	2100	WP_136264888.1	AAA family ATPase	-
ETT46_RS03965 (ETT46_03960)	rpiA	751115..751798 (+)	684	WP_136022278.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 44990.45 Da
• Isoelectric Point: 4.6116

>NTDB_id=342408 ETT46_RS03945 WP_136264886.1 745851..747080(+) (clpX) [Streptococcus pyogenes strain emm100]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDNDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=342408 ETT46_RS03945 WP_136264886.1 745851..747080(+) (clpX) [Streptococcus pyogenes strain emm100]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTCCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATAACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCACCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATCGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGCTTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCTCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATCGAAGAAA
CGATGCTTGACATCATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575