Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   ETT47_RS05610 Genome accession   NZ_CP035452
Coordinates   1121783..1123588 (-) Length   601 a.a.
NCBI ID   WP_136099202.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm123     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1116783..1128588
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT47_RS05595 (ETT47_05585) prsA 1118321..1119376 (-) 1056 WP_002984003.1 peptidylprolyl isomerase PrsA -
  ETT47_RS05600 (ETT47_05590) - 1119439..1120146 (-) 708 WP_063631966.1 O-methyltransferase -
  ETT47_RS05605 (ETT47_05595) - 1120212..1121408 (-) 1197 WP_002995765.1 OFA family MFS transporter -
  ETT47_RS05610 (ETT47_05600) pepF 1121783..1123588 (-) 1806 WP_136099202.1 oligoendopeptidase F Regulator
  ETT47_RS05615 (ETT47_05605) - 1123601..1124563 (-) 963 WP_136099203.1 competence protein CoiA -
  ETT47_RS05620 (ETT47_05610) - 1124859..1125575 (-) 717 WP_136099204.1 pseudouridine synthase -
  ETT47_RS05625 (ETT47_05615) nagB 1125694..1126398 (-) 705 WP_136099205.1 glucosamine-6-phosphate deaminase -
  ETT47_RS05630 (ETT47_05620) queA 1126600..1127628 (+) 1029 WP_023078839.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 69371.37 Da        Isoelectric Point: 4.8408

>NTDB_id=342357 ETT47_RS05610 WP_136099202.1 1121783..1123588(-) (pepF) [Streptococcus pyogenes strain emm123]
MTDNRSHLEEKYTWDLSTIFATDKDWEAEVSDLATEVEASKCFAGHLLDSSTNLLKVTKTYLELARRVEKVYVYAHMKND
QDTTVAKYQEYQAKASGLYAKFSEVFSFYDPEVMALSQEDYQAFLAETPDLKRYHHFFDKLFQTRDHVLSQAEEELLAGA
QEIFNGAEETFSILDNADIVFPVVKNDKGEDVELTHGNFISLMESKDRSVRQAAYEAMYSTYEQFQHTYAKTLQTNVKVQ
NYKARVHKYDSARQAAMAANFIPEAVYDTLLETVNKHLPLLHRYLKLRQEVLGLDDLKMYDVYTPLSETDLAIGYDEALE
KAEKVLAVFGKDYADRVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTRET
QPYVYGDYSIFLAEIASTTNENIMTEALLNEVQDEKERFAILNHYLDGFRGTVFRQTQFAEFEHAIHQADQKGEVLTSEY
LNQLYADLNEKYYGLSKKDNHFIQYEWARIPHFYYNYYVYQYATGFAAASYLADKIVHGTQDDIDHYLAYLKSGNSDYPL
EVIAKAGVDMAKGDYLEAAFKVFDERLTELEVLVSKGIHKS

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=342357 ETT47_RS05610 WP_136099202.1 1121783..1123588(-) (pepF) [Streptococcus pyogenes strain emm123]
ATGACTGATAATCGCAGCCATTTAGAAGAAAAATACACTTGGGATTTGAGCACTATTTTTGCAACAGATAAGGATTGGGA
AGCTGAAGTTAGTGACTTAGCTACTGAAGTTGAGGCATCTAAATGTTTTGCTGGTCATTTGCTGGATTCTAGTACTAATT
TGTTAAAGGTTACAAAAACATATTTAGAATTGGCTCGTCGTGTGGAGAAAGTCTATGTTTATGCTCACATGAAAAATGAC
CAAGACACTACTGTTGCCAAGTATCAAGAATACCAAGCTAAGGCTTCAGGCTTGTATGCAAAGTTTAGCGAAGTCTTTTC
ATTCTATGATCCAGAAGTTATGGCATTGAGTCAGGAAGATTACCAAGCTTTTCTTGCGGAAACACCTGATTTAAAAAGGT
ATCATCATTTCTTTGACAAATTGTTCCAGACACGTGACCATGTGCTTAGCCAGGCTGAAGAGGAATTATTAGCAGGAGCC
CAAGAAATTTTCAACGGCGCTGAAGAAACCTTTAGCATTCTGGATAACGCTGATATTGTCTTTCCAGTAGTTAAAAATGA
TAAGGGGGAAGATGTTGAATTAACCCATGGTAACTTCATTAGCCTAATGGAATCTAAGGACCGTAGCGTTCGCCAAGCTG
CTTATGAAGCCATGTATAGTACTTATGAACAGTTCCAACATACTTACGCTAAAACCTTGCAAACCAATGTGAAAGTGCAA
AACTATAAGGCGCGTGTTCATAAATACGATTCAGCTCGTCAGGCTGCCATGGCTGCTAACTTTATTCCTGAAGCTGTTTA
CGATACCTTGTTAGAAACGGTTAACAAACATTTACCACTCTTACACCGTTATTTGAAATTGCGTCAAGAGGTTCTTGGTT
TAGACGATTTGAAGATGTATGATGTTTACACACCATTATCTGAAACAGATTTAGCCATTGGTTATGATGAGGCTTTGGAA
AAGGCTGAGAAGGTTTTGGCTGTTTTTGGTAAGGATTACGCAGATCGTGTACATCGTGCTTTTACCGAACGTTGGATTGA
TGTTCACGTCAATAAAGGGAAGCGCTCTGGGGCTTATTCAGGTGGTTCCTATGATACCAATGCCTTCATGCTGTTGAACT
GGCAAGATACACTTGATAATCTTTACACACTTGTCCACGAAACAGGCCACAGTTTGCATTCTACTTTCACTCGTGAAACA
CAGCCTTATGTGTATGGGGATTATAGTATCTTCTTGGCAGAAATTGCATCCACAACGAATGAAAACATCATGACAGAAGC
TCTCTTAAATGAAGTGCAAGATGAGAAAGAACGCTTTGCCATTTTAAACCATTACCTCGATGGTTTCCGTGGAACAGTTT
TCCGTCAAACCCAATTTGCTGAGTTTGAACATGCCATTCATCAAGCTGATCAAAAAGGAGAAGTGTTAACAAGTGAATAC
CTTAACCAGCTATACGCTGATTTAAATGAAAAATATTATGGTTTAAGTAAAAAAGATAATCATTTTATTCAGTATGAATG
GGCACGTATTCCTCATTTCTATTACAATTATTATGTTTACCAATATGCAACAGGTTTTGCAGCTGCAAGCTATTTAGCGG
ATAAGATTGTGCATGGCACACAAGACGATATCGATCATTACTTGGCCTACCTCAAGTCAGGAAATTCTGATTACCCACTT
GAAGTGATTGCTAAAGCAGGCGTTGATATGGCAAAAGGTGATTATTTGGAAGCCGCCTTTAAAGTCTTTGACGAACGTCT
AACAGAACTTGAAGTACTCGTGTCCAAAGGCATACACAAAAGCTAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(202-581)

Oligopeptidase F (Peptidase_M3_N)

(112-181)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

71.048

100

0.71

Multiple sequence alignment