Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   ETT48_RS06585 Genome accession   NZ_CP035451
Coordinates   1259416..1260453 (-) Length   345 a.a.
NCBI ID   WP_002994811.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm230     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1254416..1265453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT48_RS06565 (ETT48_06560) - 1255166..1255792 (+) 627 WP_002989076.1 A24 family peptidase -
  ETT48_RS06570 (ETT48_06565) rlmN 1255874..1256953 (-) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  ETT48_RS06575 (ETT48_06570) - 1256957..1257577 (-) 621 WP_002992791.1 YutD family protein -
  ETT48_RS06580 (ETT48_06575) - 1258025..1259002 (-) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  ETT48_RS06585 (ETT48_06580) sepM 1259416..1260453 (-) 1038 WP_002994811.1 SepM family pheromone-processing serine protease Regulator
  ETT48_RS06590 (ETT48_06585) coaD 1260440..1260931 (-) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  ETT48_RS06595 (ETT48_06590) rsmD 1260921..1261460 (-) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ETT48_RS06600 (ETT48_06595) asnA 1261583..1262575 (-) 993 WP_002994813.1 aspartate--ammonia ligase -
  ETT48_RS06605 (ETT48_06600) arcC 1262888..1263838 (-) 951 WP_002994815.1 carbamate kinase -
  ETT48_RS06610 (ETT48_06605) - 1263858..1265189 (-) 1332 WP_002994817.1 dipeptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37571.27 Da        Isoelectric Point: 9.6692

>NTDB_id=342308 ETT48_RS06585 WP_002994811.1 1259416..1260453(-) (sepM) [Streptococcus pyogenes strain emm230]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTIQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
SKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=342308 ETT48_RS06585 WP_002994811.1 1259416..1260453(-) (sepM) [Streptococcus pyogenes strain emm230]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGATTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGTGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
TCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(129-192)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-310)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.696

100

0.687

Multiple sequence alignment