Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   ETT50_RS02985 Genome accession   NZ_CP035449
Coordinates   572832..573869 (+) Length   345 a.a.
NCBI ID   WP_010922499.1    Uniprot ID   A0A4U9I5V9
Organism   Streptococcus pyogenes strain emm56     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 567832..578869
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT50_RS02960 (ETT50_02960) - 568096..569427 (+) 1332 WP_032465128.1 dipeptidase -
  ETT50_RS02965 (ETT50_02965) arcC 569447..570397 (+) 951 WP_010922501.1 carbamate kinase -
  ETT50_RS02970 (ETT50_02970) asnA 570710..571702 (+) 993 WP_023611792.1 aspartate--ammonia ligase -
  ETT50_RS02975 (ETT50_02975) rsmD 571825..572364 (+) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ETT50_RS02980 (ETT50_02980) coaD 572354..572845 (+) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  ETT50_RS02985 (ETT50_02985) sepM 572832..573869 (+) 1038 WP_010922499.1 SepM family pheromone-processing serine protease Regulator
  ETT50_RS02990 (ETT50_02990) - 574283..575260 (+) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  ETT50_RS02995 (ETT50_02995) - 575708..576328 (+) 621 WP_002992791.1 YutD family protein -
  ETT50_RS03000 (ETT50_03000) rlmN 576332..577411 (+) 1080 WP_030126386.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  ETT50_RS03005 (ETT50_03005) - 577493..578119 (-) 627 WP_032465127.1 A24 family peptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37541.24 Da        Isoelectric Point: 9.6692

>NTDB_id=342184 ETT50_RS02985 WP_010922499.1 572832..573869(+) (sepM) [Streptococcus pyogenes strain emm56]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTVQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=342184 ETT50_RS02985 WP_010922499.1 572832..573869(+) (sepM) [Streptococcus pyogenes strain emm56]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGCTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGGTTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9I5V9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

69.275

100

0.693

Multiple sequence alignment