Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   ETT53_RS09020 Genome accession   NZ_CP035446
Coordinates   53551..53646 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain emm68.2     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context


Location: 48551..58646
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT53_RS00315 (ETT53_00315) purK 48618..49693 (+) 1076 Protein_29 5-(carboxyamino)imidazole ribonucleotide synthase -
  ETT53_RS00320 (ETT53_00320) - 50104..51114 (+) 1011 WP_227875640.1 hypothetical protein -
  ETT53_RS00325 (ETT53_00325) purB 51134..52426 (+) 1293 WP_002986683.1 adenylosuccinate lyase -
  ETT53_RS00330 (ETT53_00330) comR 52556..53467 (+) 912 WP_002986681.1 transcriptional regulator Rgg4/ComR Regulator
  ETT53_RS09020 comS 53551..53646 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  ETT53_RS00335 (ETT53_00335) ruvB 53693..54691 (+) 999 WP_011054100.1 Holliday junction branch migration DNA helicase RuvB -
  ETT53_RS00340 (ETT53_00340) - 54829..55266 (+) 438 WP_002994668.1 low molecular weight protein-tyrosine-phosphatase -
  ETT53_RS00345 (ETT53_00345) - 55289..55690 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  ETT53_RS00350 (ETT53_00350) - 55687..57462 (+) 1776 WP_129321522.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=342046 ETT53_RS09020 WP_198462994.1 53551..53646(+) (comS) [Streptococcus pyogenes strain emm68.2]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=342046 ETT53_RS09020 WP_198462994.1 53551..53646(+) (comS) [Streptococcus pyogenes strain emm68.2]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1

  comS Streptococcus pyogenes MGAS315

45.161

100

0.452


Multiple sequence alignment