Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   ETT53_RS03160 Genome accession   NZ_CP035446
Coordinates   594316..595353 (+) Length   345 a.a.
NCBI ID   WP_002983824.1    Uniprot ID   A0A4U9C0Q7
Organism   Streptococcus pyogenes strain emm68.2     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 589316..600353
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ETT53_RS03135 (ETT53_03135) - 589580..590911 (+) 1332 WP_011285641.1 dipeptidase -
  ETT53_RS03140 (ETT53_03140) arcC 590931..591881 (+) 951 WP_010922501.1 carbamate kinase -
  ETT53_RS03145 (ETT53_03145) asnA 592194..593186 (+) 993 WP_012560825.1 aspartate--ammonia ligase -
  ETT53_RS03150 (ETT53_03150) rsmD 593309..593848 (+) 540 WP_002983819.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  ETT53_RS03155 (ETT53_03155) coaD 593838..594329 (+) 492 WP_002983821.1 pantetheine-phosphate adenylyltransferase -
  ETT53_RS03160 (ETT53_03160) sepM 594316..595353 (+) 1038 WP_002983824.1 SepM family pheromone-processing serine protease Regulator
  ETT53_RS03165 (ETT53_03165) - 595767..596744 (+) 978 WP_002994809.1 LacI family DNA-binding transcriptional regulator -
  ETT53_RS03170 (ETT53_03170) - 597192..597812 (+) 621 WP_032464468.1 YutD family protein -
  ETT53_RS03175 (ETT53_03175) rlmN 597816..598895 (+) 1080 WP_002992788.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  ETT53_RS03180 (ETT53_03180) - 598977..599603 (-) 627 WP_129321410.1 A24 family peptidase -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37555.27 Da        Isoelectric Point: 9.6692

>NTDB_id=342020 ETT53_RS03160 WP_002983824.1 594316..595353(+) (sepM) [Streptococcus pyogenes strain emm68.2]
MKRLKKIKWWLVGLLALISLLLALFFPLPYYIEMPGGAYDIRTVLQVNGKEDKRKGAYQFVAVGISRASLAQLLYAWLTP
FTEISTAEDTTGGYSDADFLRINQFYMETSQNAAIYQALSLAGKPVTLDYKGVYVLDVNNESTFKGTLHLADTVTGVNGK
QFTSSAELIDYVSHLKLGDEVTIQFTSDNKPKKGVGRIIKLKNGKNGIGIALTDHTSVNSEDTVIFSTKGVGGPSAGLMF
TLDIYDQITKEDLRKGRTIAGTGTIGKDGEVGDIGGAGLKVVAAAEAGADIFFVPNNPVDKEIKKVNPNAISNYEEAKRA
AKRLKTKMKIVPVTTVQEALVYLRK

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=342020 ETT53_RS03160 WP_002983824.1 594316..595353(+) (sepM) [Streptococcus pyogenes strain emm68.2]
ATGAAAAGACTTAAAAAAATCAAATGGTGGTTAGTGGGTCTGCTAGCTTTAATCTCTTTGTTGCTAGCGTTATTTTTTCC
GCTACCTTATTATATTGAAATGCCTGGAGGCGCTTACGATATTCGGACTGTCTTACAAGTCAATGGCAAAGAAGACAAAC
GAAAAGGAGCTTACCAGTTTGTTGCAGTGGGCATTAGTCGTGCCAGCCTCGCTCAGCTATTATATGCTTGGCTGACACCG
TTTACTGAAATTAGTACAGCAGAAGATACAACAGGCGGATACAGCGATGCTGATTTCCTTCGAATTAATCAATTTTACAT
GGAAACATCACAAAATGCAGCTATTTATCAAGCTTTATCCTTAGCTGGAAAACCAGTTACATTAGATTATAAAGGCGTAT
ATGTTTTAGACGTAAACAACGAATCTACTTTTAAAGGAACGTTACACTTAGCAGATACTGTAACAGGTGTAAATGGTAAA
CAGTTTACTAGTTCAGCAGAACTTATTGACTATGTTTCTCACCTAAAACTAGGGGATGAAGTTACGATTCAGTTTACGAG
TGATAATAAGCCTAAAAAAGGAGTTGGCCGTATTATCAAACTGAAAAATGGGAAAAATGGGATTGGCATTGCCTTGACTG
ATCATACAAGTGTCAATTCAGAAGACACAGTGATCTTTAGTACTAAAGGAGTAGGAGGACCTAGTGCTGGTCTAATGTTT
ACTCTTGATATATATGATCAAATAACTAAAGAAGATTTACGCAAGGGCCGTACAATTGCAGGTACAGGAACTATTGGCAA
GGATGGCGAAGTAGGAGATATTGGTGGTGCAGGTCTTAAAGTAGTTGCAGCAGCTGAAGCTGGTGCAGATATATTTTTTG
TTCCGAATAATCCTGTTGATAAGGAAATTAAAAAAGTTAATCCAAATGCTATAAGTAATTACGAAGAAGCCAAACGGGCA
GCCAAACGACTAAAGACCAAAATGAAGATTGTTCCTGTTACGACTGTTCAAGAGGCACTGGTTTATCTTCGCAAATAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(233-309)

PDZ domain (PDZ_2)

(129-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4U9C0Q7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

68.986

100

0.69

Multiple sequence alignment