Detailed information
Bioinformatically predicted
Overview
| Name | radA | Type | Machinery gene |
| Locus tag | ETT53_RS01300 | Genome accession | NZ_CP035446 |
| Coordinates | 218254..219615 (+) | Length | 453 a.a. |
| NCBI ID | WP_111693002.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain emm68.2 | ||
| Function | homologous recombination (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 182657..218173 | 218254..219615 | flank | 81 |
Gene organization within MGE regions
Location: 182657..219615
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| ETT53_RS01135 (ETT53_01135) | - | 182657..183853 (+) | 1197 | WP_002986345.1 | glycine betaine/L-proline ABC transporter ATP-binding protein | - |
| ETT53_RS01140 (ETT53_01140) | - | 183871..185598 (+) | 1728 | WP_111684531.1 | ABC transporter permease/substrate binding protein | - |
| ETT53_RS01145 (ETT53_01145) | polA | 185729..188371 (+) | 2643 | WP_115353961.1 | DNA polymerase I | - |
| ETT53_RS01150 (ETT53_01150) | - | 188549..189004 (+) | 456 | WP_032460942.1 | CoA-binding protein | - |
| ETT53_RS01155 (ETT53_01155) | perR | 189056..189523 (+) | 468 | WP_002986328.1 | peroxide-responsive transcriptional repressor PerR | - |
| ETT53_RS01160 (ETT53_01160) | - | 189742..189978 (+) | 237 | WP_014635252.1 | hypothetical protein | - |
| ETT53_RS01165 (ETT53_01165) | - | 190200..191534 (+) | 1335 | WP_002987923.1 | phosphoadenosine phosphosulfate reductase | - |
| ETT53_RS01170 (ETT53_01170) | - | 191527..192057 (+) | 531 | WP_002987925.1 | ParB/RepB/Spo0J family partition protein | - |
| ETT53_RS08755 | - | 192104..192253 (-) | 150 | Protein_180 | ISL3 family transposase | - |
| ETT53_RS01180 (ETT53_01180) | - | 192386..193536 (-) | 1151 | Protein_181 | IS3 family transposase | - |
| ETT53_RS01185 (ETT53_01185) | - | 193614..194924 (-) | 1311 | WP_129321561.1 | SLC13 family permease | - |
| ETT53_RS01190 (ETT53_01190) | nadC | 195148..196020 (+) | 873 | WP_002992869.1 | carboxylating nicotinate-nucleotide diphosphorylase | - |
| ETT53_RS01195 (ETT53_01195) | - | 196320..197661 (-) | 1342 | Protein_184 | IS3 family transposase | - |
| ETT53_RS01200 (ETT53_01200) | - | 197747..198610 (-) | 864 | WP_032463137.1 | DUF975 family protein | - |
| ETT53_RS08970 (ETT53_01205) | - | 198647..198832 (+) | 186 | WP_002986321.1 | hypothetical protein | - |
| ETT53_RS01210 (ETT53_01210) | tgt | 198829..199971 (+) | 1143 | WP_011528208.1 | tRNA guanosine(34) transglycosylase Tgt | - |
| ETT53_RS01215 (ETT53_01215) | - | 200189..200500 (+) | 312 | WP_002987947.1 | CHY zinc finger protein | - |
| ETT53_RS01220 (ETT53_01220) | - | 200504..201043 (+) | 540 | WP_002986314.1 | biotin transporter BioY | - |
| ETT53_RS01225 (ETT53_01225) | - | 201183..201962 (+) | 780 | WP_002986311.1 | MBL fold metallo-hydrolase | - |
| ETT53_RS01230 (ETT53_01230) | tadA | 201962..202477 (+) | 516 | WP_002992549.1 | tRNA adenosine(34) deaminase TadA | - |
| ETT53_RS01235 (ETT53_01235) | - | 203091..204323 (-) | 1233 | WP_047235636.1 | transglutaminase domain-containing protein | - |
| ETT53_RS01245 (ETT53_01245) | speG | 204723..205427 (+) | 705 | WP_002991212.1 | streptococcal pyrogenic exotoxin SpeG | - |
| ETT53_RS01250 (ETT53_01250) | - | 205887..207236 (+) | 1350 | WP_014635263.1 | glucose-6-phosphate isomerase | - |
| ETT53_RS01255 (ETT53_01255) | - | 207585..209093 (-) | 1509 | WP_111674459.1 | helix-turn-helix domain-containing protein | - |
| ETT53_RS01260 (ETT53_01260) | - | 209781..210452 (+) | 672 | WP_011017305.1 | rhomboid family intramembrane serine protease | - |
| ETT53_RS01265 (ETT53_01265) | galU | 210551..211450 (-) | 900 | WP_002986125.1 | UTP--glucose-1-phosphate uridylyltransferase GalU | - |
| ETT53_RS01270 (ETT53_01270) | - | 211483..212499 (-) | 1017 | WP_002986123.1 | NAD(P)H-dependent glycerol-3-phosphate dehydrogenase | - |
| ETT53_RS01275 (ETT53_01275) | - | 212797..213246 (+) | 450 | WP_002986120.1 | MarR family winged helix-turn-helix transcriptional regulator | - |
| ETT53_RS01280 (ETT53_01280) | - | 213239..214945 (+) | 1707 | WP_111674460.1 | ABC transporter ATP-binding protein | - |
| ETT53_RS01285 (ETT53_01285) | - | 214948..216732 (+) | 1785 | WP_002986115.1 | ABC transporter ATP-binding protein | - |
| ETT53_RS01290 (ETT53_01290) | - | 216850..217617 (+) | 768 | WP_002986113.1 | epoxyqueuosine reductase QueH | - |
| ETT53_RS01295 (ETT53_01295) | - | 217727..218173 (+) | 447 | WP_002986111.1 | dUTP diphosphatase | - |
| ETT53_RS01300 (ETT53_01300) | radA | 218254..219615 (+) | 1362 | WP_111693002.1 | DNA repair protein RadA | Machinery gene |
Sequence
Protein
Download Length: 453 a.a. Molecular weight: 49382.69 Da Isoelectric Point: 6.0962
>NTDB_id=342005 ETT53_RS01300 WP_111693002.1 218254..219615(+) (radA) [Streptococcus pyogenes strain emm68.2]
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGPVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
MAKKKATFICQECGYQSPKYLGRCPNCSAWSSFVEEVEVKEVKNARVSLAGEKSRPVKLKDVDNISYHRTQTDMSEFNRV
LGGGVVPGSLILIGGDPGIGKSTLLLQVSTQLANKGPVLYVSGEESAEQIKLRSERLGDIDNEFYLYAETNMQAIRTEIE
NIKPDFLIIDSIQTIMSPDITGVQGSVSQVREVTAELMQLAKTNNIATFIVGHVTKEGTLAGPRMLEHMVDTVLYFEGER
HHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNPSQVFLEERLDGATGSAVVVTMEGSRPILAEVQSLVTPTVFGNAR
RTTTGLDFNRVSLIMAVLEKRCGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKEKPTSPQEAFLGEIGLTGEIR
RVTRIEQRINEAAKLGFTKVYAPKNALQGIDIPQGIEVVGVTTVGQVLKAVFS
Nucleotide
Download Length: 1362 bp
>NTDB_id=342005 ETT53_RS01300 WP_111693002.1 218254..219615(+) (radA) [Streptococcus pyogenes strain emm68.2]
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGACCGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGTACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGACCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATCGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGATTTACCAAGGTCTATGCTCCTAAAAATGCCTT
ACAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
ATGGCAAAGAAAAAAGCAACCTTTATCTGTCAGGAGTGTGGCTACCAGTCGCCAAAGTATTTAGGGCGCTGTCCAAATTG
CTCGGCCTGGTCTTCTTTTGTGGAAGAAGTAGAGGTCAAAGAAGTCAAAAATGCCCGTGTTAGTCTAGCTGGAGAAAAGT
CCAGACCGGTTAAACTAAAAGATGTGGATAATATTAGTTATCACAGAACACAGACTGACATGTCTGAATTTAATAGAGTT
CTTGGAGGGGGTGTGGTTCCTGGAAGCTTGATTTTAATTGGTGGTGATCCAGGTATTGGAAAATCCACCTTACTCTTGCA
GGTATCCACGCAGCTCGCTAATAAGGGACCGGTTCTCTATGTGTCTGGGGAAGAATCAGCAGAGCAGATTAAACTGCGGA
GTGAGCGTCTGGGTGATATTGACAATGAATTTTACCTCTATGCCGAAACCAATATGCAAGCTATTCGTACAGAAATTGAA
AATATTAAACCAGATTTTTTAATTATTGACTCCATTCAGACCATCATGAGCCCTGATATTACAGGTGTTCAAGGATCAGT
CAGTCAGGTGAGAGAAGTCACTGCAGAATTGATGCAGCTTGCAAAGACGAACAACATTGCAACCTTTATTGTGGGTCATG
TCACCAAGGAAGGAACCTTGGCTGGACCTCGTATGTTAGAACACATGGTGGATACCGTTCTCTACTTTGAAGGGGAAAGG
CATCACACCTTTCGCATTCTTCGGGCTGTGAAAAACCGCTTTGGCTCCACTAACGAGATCGGCATCTTTGAAATGCAGTC
TGGCGGCTTGGTAGAGGTCTTAAATCCTAGTCAAGTCTTTTTAGAGGAACGCTTAGATGGGGCAACAGGATCGGCTGTCG
TTGTAACGATGGAAGGAAGTCGTCCTATCTTAGCAGAGGTGCAATCTTTAGTGACACCAACCGTTTTTGGCAATGCCAGA
CGAACCACTACGGGACTTGATTTCAATCGCGTAAGCCTAATAATGGCAGTTTTAGAAAAGCGCTGTGGTTTACTCTTACA
AAATCAAGATGCCTACCTCAAGTCGGCTGGTGGTGTCAAACTAGACGAACCTGCCATTGATTTGGCAGTCGCTGTGGCTA
TCGCATCCAGTTATAAGGAAAAACCAACCAGCCCTCAAGAAGCTTTCTTAGGCGAGATCGGGTTAACAGGTGAGATTCGG
CGAGTGACCCGTATTGAGCAACGGATTAATGAAGCAGCAAAGCTTGGATTTACCAAGGTCTATGCTCCTAAAAATGCCTT
ACAAGGCATTGATATCCCTCAAGGTATTGAGGTTGTCGGAGTGACTACGGTTGGTCAGGTTTTAAAGGCAGTTTTTAGCT
AG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| radA | Streptococcus mitis NCTC 12261 |
85.651 |
100 |
0.857 |
| radA | Streptococcus pneumoniae D39 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae R6 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae Rx1 |
85.43 |
100 |
0.854 |
| radA | Streptococcus mitis SK321 |
85.43 |
100 |
0.854 |
| radA | Streptococcus pneumoniae TIGR4 |
85.43 |
100 |
0.854 |
| radA | Bacillus subtilis subsp. subtilis str. 168 |
61.369 |
100 |
0.614 |